Apoptosis Reagents and Kits
Apexbio Technology LLC Annexin V-Cy3 Apoptosis Kit, 100 assays. Cas: MFCD: NA. Detects Apoptosis within 10 min.
Annexin V is a cellular protein, which plays important roles in the inhibition of the activity of phospholipase A1 and blood coagulation by competing for phosphatidylserine (PS) binding sites with prothrombin. Annexin V has a high affinity to PS and is used as a probe to detect cells that have expressed PS on the cell surface. After initiating apoptosis, cells translocate phosphatidylserine (PS) from the inner face of the plasma membrane to the cell surface soon, which can be easily detected by Annexin V.Annexin V-Cy3 Apoptosis Detection Kit uses a fluorescent conjugate of Annexin V that can easily detect PS on the cell surface after initiating apoptosis. The one-step staining procedure needs only 10 minutes. The result can be analyzed by fluorescence microscopy or by flow cytometry. Other sizes are also available. Please inqury us for quote.
Medchemexpress LLC Tasisulam | 519055-62-0 | 99.8% | 415.11 | 50 MG
Tasisulam is an anticancer agent that induces apoptosis via the intrinsic pathway, leading to cytochrome c release and caspase-dependent cell death. It inhibits mitotic progression and induces vascular normalization.
- Induces apoptosis via the intrinsic pathway
- Leads to cytochrome c release and caspase-dependent cell death
- Inhibits mitotic progression
- Induces vascular normalization
- Demonstrates antiproliferative response across tumor histologies
- Increases 4N DNA and G2-M accumulation
- Blocks VEGF, epidermal growth factor, and fibroblast growth factor-induced endothelial cell cord formation
Biotium Mitochondrial Marker113-1 CF647 conjugate 0.1mgmL
Mitochondrial Marker113-1 CF647 conjugate 0.1mgmL
Biotium CF594 TUNEL Assay Apoptosis Detection Kit
In the TUNEL assay, TdT enzyme catalyzes the addition of labeled dUTP to the 3'- ends of the internucleosomal DNA strand breaks that are a hallmark of apoptosis. The CF dye TUNEL Assay Apoptosis Detection Kit employs dUTP conjugated to Biotium's exceptionally bright and photostable CF fluorescent dyes, for single step fluorescent TUNEL labeling of fixed cells or tissues for analysis by fluorescence microscopy or flow cytometry. This kit contains CF594 which has an excitation/emission of 593/614 nm. The kit has reagents sufficient for 50 reactions.
Abcam Human NQO1 Antibody Pair - BSA and Azide free, 10 x 96 Tests
Human NQO1 Antibody Pair - BSA and Azide free is a kit containing recombinant capture and detector antibodies in a carrier-free formulation for the measurement of Human NQO1.
The product is subject to the following: Abcam Restricted Use Statement
Abcam DNase I Assay Kit (Fluorometric)
DNase I Assay Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Vector Biolabs CASP8 and FADD-like apoptosis regulator Adenovirus (Ad-FLIP)
FLIP (FLICE inhibitory protein), also designated CLARP, Casper, I-FLICE, FLAME-1 and MRIT, is expressed as both long (FLIPL) and short (FLIPS) isoforms and is involved in the regulation of apoptosis. The short form of FLIP contains two death effector domains homologous to the death effector domain of the FAS-associating protein FADD. The long form of FLIP contains an additional caspase-like domain, but lacks a catalytic active site and the residues that form the substrate binding pocket in most caspases.
Medchemexpress LLC N-carbobenzoxy-D-homoserine | 41088-85-1 | MFCD12545887 | 253.25 g/mol | C12H15NO5 | 5 G
N-Carbobenzoxy-D-homoserine (N-(Benzyloxycarbonyl)-D-homoserine) is the D-enantiomer of homoserine bearing an N-carbobenzoxy (Cbz) protecting group. Supplied as a powder, it is used as a synthetic intermediate in organic and peptide synthesis, including preparation of antibody-drug conjugates and other constructs that require temporary N-protection.
- Powdered synthetic intermediate for organic synthesis.
- Contains N-carbobenzoxy (Cbz) protecting group for the amino function.
- Suitable for peptide synthesis and antibody-drug conjugate payload or linker preparation.
- Molecular formula C12H15NO5; molecular weight 253.25 g/mol.
- Recommended storage: powder -20°C for long term, 4°C for short term.
ABclonal Technology Caspase-9 Rabbit pAb
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1, this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.
Abcam Human VEGF Receptor 2 Antibody Pair - BSA and Azide free, 10 x 96 Tests
Human VEGF Receptor 2 Antibody Pair - BSA and Azide free is a kit containing recombinant capture and detector antibodies in a carrier-free formulation for the measurement of Human VEGF Receptor 2.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Ac-IEPD-CHO, granzyme B and caspase-8 inhibitor, 1MG
MW 498.5 Da, Purity >95%. Ac-IEPD-CHO, granzyme B and caspase-8 inhibitor. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement