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Assays, reagents, kits, and other assorted products used to detect cellular apoptosis, determine the activity levels of caspase or cathepsin, or identify similar cellular activity.
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A-1155463 (CAS 1235034-55-5) is a potent and selective small-molecule inhibitor of the anti-apoptotic protein BCL-XL exhibiting a Ki of 19 nM Developed through NMR fragment screening and structure-guided optimization A-1155463 demonstrates higher efficacy against BCL-XL-dependent cell lines compared to earlier inhibitors such as WEHI-539 In murine models administration of A-1155463 induces transient thrombocytopenia and inhibits the growth of BCL-XL-dependent H146 xenograft tumors supporting its utility for mechanistic studies on BCL-XL in tumor cell survival and therapeutic resistance The compound remains in preclinical research stages
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Human/Monkey IL-4 Antibody Pair - BSA and Azide free is a kit containing recombinant capture and detector antibodies in a carrier-free formulation for the measurement of Human/Monkey IL-4.
A cell-permeable, fluorescent probe for DNA (ex. 352 nm/em. max 461 nm) that is useful as a marker of nuclei for cell cycle and to distinguish nuclear morphology in apoptotic cells
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Annexin A7 Primary Antibody Unconjugated Public Immunogen Range 1-150/488 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
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MW 540.7 Da, Purity >95%. Potent inhibitor of CRM-1-mediated (exportin-1) nuclear export. Displays antibiotic, antifungal, and antitumor properties and blocks the cell cycle at G₁ and G₂ phases. Potent inhibitor of nucleo-cytoplasmic translocation of Rev. Also shown to suppress HIV-1 replication in human monocytes (IC₅₀ = 600 pM).
Human Tissue Factor Antibody Pair - BSA and Azide free is a kit containing recombinant capture and detector antibodies in a carrier-free formulation for the measurement of Human Tissue Factor.
Based on the detection of AFC (7-amino-4-trifluoromethyl coumarin) after cleavage from the labelled substrate DEVD-AFC. Alternative name: CPP32, Yama, Apopain. Applications: Fluorescent detection Activity assay.
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