Apoptosis Reagents and Kits
STEMCELL Technologies Annexin V Apoptosis Detection Kit with 7-AAD, PE, Size: 100 Tests
This apoptosis staining and detection kit is used for the combined detection of early-stage cell apoptosis (using Annexin V) and late-stage cell apoptosis or necrosis (using both Annexin V and 7-AAD). It includes Annexin V (Catalog #100-0329 or Catalog #100-0331 or Catalog #100-0333), Annexin V Binding Buffer (Catalog #100-0334), and 7-AAD (Catalog #75001). Annexin V belongs to the Annexin family of intracellular proteins that bind to membrane phospholipids in a calcium-dependent manner. This dye has a high affinity for phosphatidylserine (PS) that is present in the inner leaflet of the plasma membrane. During early-stage cell apoptosis, PS is translocated from the inner to the outer leaflet of the cell membrane, exposing it to the external environment, where it is detected by Annexin V. Visit STEMCELL.com for more information and related products.
Cayman Chemical Z-VAD-AMCacetate 1mg
A caspase-1 fluorogenic substrate; upon enzymatic cleavage, AMC is released and its fluorescence can be used to quantify enzyme activity; ex/em = 340-360/440-460 nm, respectively
Abcam Human NLRP3 Antibody Pair - BSA and Azide free, 10 x 96 Tests
Human NLRP3 Antibody Pair - BSA and Azide free is a kit containing recombinant capture and detector antibodies in a carrier-free formulation for the measurement of Human NLRP3.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human IL-33 Antibody Pair - BSA and Azide free, 10 x 96 Tests
Human IL-33 Antibody Pair - BSA and Azide free is a kit containing recombinant capture and detector antibodies in a carrier-free formulation for the measurement of Human IL-33.
The product is subject to the following: Abcam Restricted Use Statement
Biolegend FITC anti-human CD70
FITC anti-human CD70 [113-16]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 25 tests
Cayman Chemical Z-VEID-AFCtrIfluoroacetate 1mg
A fluorogenic substrate for caspase-6; AFC is released upon enzymatic cleavage by caspase-6 and its fluorescence can be used to quantify caspase-6 activity; ex/em = 400/505 nm, respectively
Cayman Chemical Z-YVAD-CMKtrIfluoroacetate 1mg
An inhibitor of caspase-1 and caspase-3; reduces IL-1β and IL-18 secretion in isolated mouse peritoneal macrophages by cholesterol-treated rPLY at 30 µM; reduces caspase-3 activation by the EGF-like domain of tenascin-C in detached hSMCs in vitro; decreases cell death induced by the EGF-like domain of tenascin-C by 50% at 100 µM; completely inhibits cell death of hSMCs at 200-400 µM
Abcam Human CEA Antibody Pair - BSA and Azide free, 10 x 96 Tests
Human CEA Antibody Pair - BSA and Azide free is a kit containing recombinant capture and detector antibodies in a carrier-free formulation for the measurement of Human CEA.
The product is subject to the following: Abcam Restricted Use Statement
Selleck Chemical LLC Z-IETD-FMK 1mg 210344-98-2 Caspase-8 Inhibitor
Z-IETD-FMK (Caspase-8 Inhibitor) is a specific Caspase-8 inhibitor. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Enzo Life Sciences SUPERFASLIGAND Protein (soluble) (human), (recombinant) (5µg)
SUPERFASLIGAND (soluble) (human), (recombinant) features an N-terminus linker shown to improve stability and enhance immune activation compared to recombinant ligands alone. SUPERFASLIGAND (soluble) (human), (recombinant) features an N-terminus linker shown to improve stability and enhance immune activation compared to recombinant ligands alone. Alternative name: FasL (oligomer), APO-1L (oligomer), CD95L (oligomer), CD178 (oligomer), TNFSF 6 (oligomer). Concentration: 0.1mg/ml after reconstitution. Purity: ≥95% (SDS-PAGE). Formulation: Lyophilized. Contains PBS. Source: Produced in HEK 293 cells. The extracellular domain of human FasL (APO-1L; CD95L; CD178) (aa 103-281) is fused at the N-terminus to a linker peptide (26 aa) and a FLAG-tag. Glycosylation of rhs SUPERFASLIGAND is similar to natural human FasL. Specificity: Binds to human, mouse and rat Fas (CD95; APO-1). Long Term Storage: -20°C. Applications: ELISA .
Enzo Life Sciences Apoptosis Activator 2 (25mg). CAS: 79183-19-0
Induces apoptosis by promoting the oligomerization of Apaf-1 into the mature, functional apoptosome, triggering caspase-9 activation resulting in activated caspase-3. Shows strong selectivity for cancer cells against normal cell lines. Acts in a similar way like apoptosis inducer PETCM (ALX-420-031). Alternative name: 1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (5mg/ml), methanol (5mg/ml) or 100% ethanol. Long Term Storage: +4°C.
Abcam Human KRT7 knockout A549 cell lysate.
Human KRT7 knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement