Apoptosis Reagents and Kits
Abcam Human RAB27A knockout A549 cell lysate.
Human RAB27A knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
STEMCELL Technologies Annexin V Apoptosis Detection Kit with 7-AAD, FITC, Size: 100 Tests
This apoptosis staining and detection kit is used for the combined detection of early-stage cell apoptosis (using Annexin V) and late-stage cell apoptosis or necrosis (using both Annexin V and 7-AAD). It includes Annexin V (Catalog #100-0329 or Catalog #100-0331 or Catalog #100-0333), Annexin V Binding Buffer (Catalog #100-0334), and 7-AAD (Catalog #75001). Annexin V belongs to the Annexin family of intracellular proteins that bind to membrane phospholipids in a calcium-dependent manner. This dye has a high affinity for phosphatidylserine (PS) that is present in the inner leaflet of the plasma membrane. During early-stage cell apoptosis, PS is translocated from the inner to the outer leaflet of the cell membrane, exposing it to the external environment, where it is detected by Annexin V. Visit STEMCELL.com for more information and related products.
Abcam Human PDCD6 (ALG-2) knockout HEK-293T cell lysate.
Human PDCD6 (ALG-2) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical Z-VAD OH-FMK 5mg
An irreversible tripeptide inhibitor of all caspases; useful in studies involving recombinant, isolated, or purified enzymes
American Research Products Inc Human AnneXin V ANX V ELISA K
Human AnneXin V ANX-V ELISA Kit from CUSABIO Detection Range 0 312 ng/mL-20 ng/mL Sensitivity 0 078 ng/mL Sample serum plasma cell culture supernates cell lysates Method Sandwich
Biotium CF594 TUNEL Assay Apoptosis Detection Kit
In the TUNEL assay, TdT enzyme catalyzes the addition of labeled dUTP to the 3'- ends of the internucleosomal DNA strand breaks that are a hallmark of apoptosis. The CF dye TUNEL Assay Apoptosis Detection Kit employs dUTP conjugated to Biotium's exceptionally bright and photostable CF fluorescent dyes, for single step fluorescent TUNEL labeling of fixed cells or tissues for analysis by fluorescence microscopy or flow cytometry. This kit contains CF594 which has an excitation/emission of 593/614 nm. The kit has reagents sufficient for 50 reactions.
Biotium Apoptotic, Necrotic & Healthy Cells Quantification Kit (50 assays)
This kit provides a convenient assay for quantifying apoptotic (green) and necrotic (red) cells within the same cell population by flow cytometry or fluorescence microscopy. The kit contains FITC-Annexin V which binds to apoptotic cells by binding to phosphatidylserine (PS) exposed on the cell surface, and Ethidium Homodimer III (EthD-III) which is a membrane impermeant nucleic acid probe specific for dead cells. Staining is rapid, requiring only a single 15-30 minute staining step. FITC-Annexin V has an excitation emission of 498/517 nm, and EthD-III has an excitation/emission of 522/593 nm (and a large absorption peak at 279 nm) when bound to DNA. The kit also contains a membrane permeable DNA dye Hocechst 3342 to stain all cell nuclei blue for analysis of healthy cells. The kit has reagents sufficient reagent for 50 assays.
Medchemexpress LLC HY-130250 5mg Medchemexpress, SR-4835 CAS:2387704-62-1 Purity:>98%
Medchemexpress, HY-130250 5mg SR-4835 CAS:2387704-62-1 SR-4835 is a potent, highly selective and ATP competitive dual inhibitor of CDK12/CDK13 (CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM). SR-4835 acts in synergy with DNA-damaging chemotherapy and PARP inhibitors and provokes triple-negative breast cancer (TNBC) cell death. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Biotium Annexin V, CF350 Conjugate
Annexin V fluorescent conjugates can be used to detect apoptotic cells. The human anticoagulant Annexin V is a 35-36 kDa calcium-dependent phospholipid-binding protein with high affinity for phosphatidylserine (PS). In normal viable cells, PS is located on the inner leaflet of the cytoplasmic membrane. In apoptotic cells, however, PS is translocated from the inner to the outer leaflet of the plasma membrane, where it can be detected by fluorescently labeled Annexin V. CF Dye Annexin V Conjugates are provided at 50 ug/mL in buffer with azide as a preservative. CF dyes are Biotium's line of next-generation fluorescent dyes with advantages in brightness, photostability, and conjugate specificity compared to other fluorescent dyes. UV-excitable blue fluorescent CF350 dye has excitation/emission at 347/448 nm.
Biotium Annexin V, CF770
Near-IR CF dye Annexin V conjugate is Annexin V labeled with our superior near-IR fluorescent dyes. Annexin V is a 35-36 kDa protein that has a high affinity for phosphatidylserine (PS). In normal viable cells, PS is located on the cytoplasmic surface of the cell membrane. In apoptotic cells, however, PS is translocated from the inner to the outer leaflet of the plasmic membrane, making itself available for Annexin V binding. CF dyes are Biotium's line of next-generation fluorescent dyes with advantages in brightness, photostability, and conjugate specificity compared to other fluorescent dyes. Near-infrared fluorescent CF770 dye has excitation/emission at 770/797 nm. Near-IR CF Dye Annexin V does not contain azide or other potentially toxic materials, and thus is suitable for in vivo imaging.
American Research Products Inc ANNEXIN V APC APOP KIT CV0002
5000265580 ANNEXIN V APC APOP KIT CV0002
Cell Signaling Technology PTMScanR Cleaved Caspase Substrate Motif DETSAD Kit 1 Kit
PTMScanR Cleaved Caspase Substrate Motif DETSAD Kit 1 Kit
Biotium Staurosporine, 100ug
Staurosporine is a potent and cell-permeable inhibitor of a wide variety of protein kinases including protein kinase C (IC50 = 0.7 nM), protein kinase A (IC50 = 7 nM), and protein kinase G (IC50 = 8.5 nM). Staurosporine induces apoptosis in human neuroblastoma cells and chick embryonic neurons. Properties: Soluble in DMSO or ethanol; Store at -20°C; C28H26N4O3; MW: 466.20; [62996-74-1]
Ubpbio Nutlin-3, 5MG
Nutlin-3 is a potent and selective small chemical compound that binds murine double minutes (MDM2) and blocks the MDM2/p53 interaction, by which nutlin-3 functions to stabilize p53 and induces senescence in cancer cells that express wild type p53.
Abcam Assay Kits, Enzyme substrates, Enzyme substrates for Proteases, Sulforhodamine Poly Caspases Assay Kit - 25tests, SR-FLICA Apoptosis Detection Kits use a novel approach to detect active caspases, 1 kit
Assay Kits, Enzyme substrates, Enzyme substrates for Proteases, Sulforhodamine Poly Caspases Assay Kit - 25tests, SR-FLICA Apoptosis Detection Kits use a novel approach to detect active caspases, 1 kit
The product is subject to the following: Abcam Restricted Use Statement