Signal Transduction Reagents and Kits
Medchemexpress LLC Tulobuterol | 41570-61-0 | MFCD00867022 | 99.7% | 100 MG
Tulobuterol is a long-acting β2-adrenoceptor agonist that helps reduce the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. This sympathomimetic agent is also used as a transdermal patch, increasing normal diaphragm muscle strength. It is intended for research use only.
- Acts as a β2-adrenoceptor agonist
- Reduces RV14 RNA levels and sICAM-1 concentrations in infected cells
- Decreases acidic endosome numbers and fluorescence
- Inhibits RV14 infection-induced secretion of inflammatory cytokines (IL-1β, IL-6, and IL-8)
- Restores and maintains diaphragm muscle contractility
Montana Molecular Green Downward GENIe cGMP Sensor Kit D0800G, 30mL, CMV
Measure cyclic GMP (cGMP) signaling dynamics and ascertain the specificity of PDE inhibitors or SNP activators with this live cell fluorescent assay. Add GENIe to your cells and measure robust signals the next day on an automated plate reader or fluorescence imaging system. Decreasing green fluorescence indicates cGMP increase. The assay is genetically encoded and packaged in BacMam for efficient transduction in most cell types - including uniform and near 100% efficiency in HEK293 cells as well as expression in many primary or iPSC-derived cells. Kit includes soluble guanylate cyclase..
Enzo Life Sciences (2R,4R)-APDC (1mg). CAS: 169209-63-6
Selective agonist for group II mGluRs. Inhibits the NADPH-oxidase dependent ROS system. Alternative name: LY-314,593, (2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylic acid. Purity: ≥98% (HPLC). Solubility: Soluble in water. Long Term Storage: Ambient.
Selleck Chemical LLC SB202190 (FHPI) 100mg 152121-30-7
SB202190 (FHPI) is a potent p38 MAPK inhibitor targeting p38?/? with IC50 of 50 nM/100 nM in cell-free assays, sometimes used instead of SB 203580 to investigate potential roles for SAPK2a/p38 in vivo. SB202190 inhibits endothelial cell apoptosis via induction of autophagy and heme oxygenase-1. SB202190 significantly suppresses Erastin?dependent ferroptosis. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Echelon Biosciences Research Labs 1-Hydroxy-2-methyl-2-buten-4-yl 4-diphosphate (HDMAPP) 1 mg
1-Hydroxy-2-methyl-2-buten-4-yl 4-diphosphate (HDMAPP or HMBPP) is an intermediate in the non-mevalonate pathway and is biosynthesized from 2-C-Methyl-D-erythritol 2,4-cyclophosphate (cMEPP) by IspG (GcpE). It is the substrate for IspH (LytB) yielding IPP and DMAPP. In addition, HDMAPP is the most potent VgVd T-cell activator identified. This item is non returnable
Sigma Aldrich Fine Chemicals Biosciences Calpeptin >=98% (HPLC) | 117591-20-5 | MFCD00155623 | 25MG
Calpeptin >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 362.46 | 117591-20-5 | MFCD00155623 | 25MG
Carnabio Usa Inc CK2A1/B(CSNK2A1/B)/5UG/FULL-LE
CK2a1/b(CSNK2A1/B), Full-length(CK2a1), Wild type, Amino Acid 1-391(CK2a1), 1-215(CK2b), NP_001886.1(CK2a1), NP_001311.3(Ck2b1), Expressed in Insect (sf21); 5microg
CPC Scientific Ac-Tyr-Val-Lys-Asp-CHO 1MG
Affinity ligand for interleukin-1b converting enzyme. Slow binding caspase-1 (ICE) inhibitor with low selectivity.SEQUENCE: Ac-Tyr-Val-Lys-Asp-CHOONE-LETTER SEQUENCE: Ac-YVKD-CHOMOLECULAR FORMULA: C26H39N5O8MOLECULAR WEIGHT: 549.6STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [147821-01-1]SYNONYMS: RESEARCH AREA: ApoptosisREFERENCES:T.L. Graybill et al., Int. J. Peptide Protein Res., 44, 173 (1994)N.A. Thornbery et al., Nature, 356, 768 (1992)SKU(s): CASP-015A
Apexbio Technology LLC Zolmitriptan 139264-17-8 100mg
Zolmitriptan (CAS 139264-17-8) is a synthetic small molecule that functions as a selective agonist of serotonin 5-HT1B and 5-HT1D receptors By stimulating these receptors zolmitriptan modulates trigeminovascular neurotransmission leading to cranial vasoconstriction and inhibition of pro-inflammatory neuropeptide release These mechanisms underlie its ability to acutely alleviate migraine attacks both with and without aura as well as cluster headaches In biomedical research zolmitriptan serves as a tool compound for investigating serotonergic signaling pathways involved in nociception and vascular regulation associated with headache disorders
Echelon Biosciences Research Labs PI(4,5)P2 PolyPIPosomes 0.25 mL
PolyPIPosomes are polymerized liposomes that show markedly increased stability (up to 6 months) vs. conventional liposomes. A biotin tag is incorporated for easy detection of PIPn-binding proteins with streptavidin reagents. PolyPIPosomes are provided as a 1mM total lipid solution containing 5% PIP. Each order of 250 L or 1 mL of PolyPIPosomes includes 100 L of Control PolyPIPosomes. This item is non returnable
Creative Biomart Human F7/Coagulation factor VII human
The product is human serine protease type enzyme that is involved in the extrinsic coagulation cascade which results in blood clotting.
Echelon Biosciences Research Labs PI(5)P DIC8 AMMONIUM SALT 100 ug
Phosphatidylinositol 5-phosphate diC8 (PI(5)P diC8) is a synthetic, purified dioctanoyl PI(5)P.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 5-phosphate (PI(5)P) is a rare lipid found in the nucleus that can bind the PHD finger of the nuclear adapter protein ING2. PI(5)P is phosphorylated to PI(4,5)P2 by Type II PIP kinases. This item is non returnable