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Reaction buffers for use in experiments involving modifying enzymes. Different buffer solutions create optimal reaction conditions for specific modifying enzymes, or facilitate multiple enzymatic reactions.
Casein kinase inhibitor A86 is a potent small-molecule inhibitor of casein kinase 1α (CK1α) with reported activity against CDK7 and CDK9. Supplied as a 10 mM solution in DMSO, it is intended for biochemical and cell-based research applications, including studies of apoptosis and leukemia-related signaling pathways.
Potent CK1α inhibitor with activity against CDK7 and CDK9.
Supplied as a 10 mM solution in DMSO for ready use in assays.
High purity suitable for research: 99.3%.
Molecular formula C18H25FN6; molecular weight 344.43 g/mol.
Volume 1 mL, convenient for small-scale experiments.
For research use only; not for human therapeutic applications.
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Pyruvate Kinase (PK) is a glycolysis enzyme and has four isozymes L R M1 and M2. The L isozyme is localized in gluconeogenic tissues particularly in the liver. Whereas the R and M1 are localized in the adult skeletal muscles heart brain and erythrocytes respectively. M2 is localized in the nucleus of the cells.
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Also available in 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Casein kinase 1(delta)-IN-1 (WAY-643895) is an inhibitor of casein kinase 1(delta) (CK1(delta)) which inhibits CK1(delta). Casein kinase 1(delta)-IN-1 can be used in the study of neurodegenerative diseases such as Alzheimer's disease. purity: 99%
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Many cellular processes are regulated by reversible phosphorylation of proteins and approximately 30% of proteins may become phosphorylated during their lifetime Cellular crude extracts contain numerous endogenous enzymes such as phosphatases and proteases which can degrade and modify proteins present in the extract Addition of inhibitors for these enzymes is the optimal approach for maximizing intact protein yield Phosphatase Inhibitor Cocktail 1 inhibits alkaline phosphatase L-isoenzymes and serine/threonine phosphatases such as protein phosphatases 1 and 2A (PP1 and PP2A) It has been optimized and tested in cell extracts from various animal tissues This Phosphatase Inhibitor Cocktail 1 contains Cantharidin Bromotetramisole and Microcystin LR It is supplied as a ready-to-use solution in DMSO
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