Modifying Enzymes
Cayman Chemical N-Oleoyl GlutamIn 1mg
An endogenous N-acyl amine; induces mitochondrial uncoupling to increase respiration in C2C12 cells by 64% at 50 µM; inhibits capsaicin-induced calcium flux in HEK293A cells co-transfected with TRPV1 and RFP; reduces the number of acetic acid-induced abdominal constrictions, as well as formalin-induced paw licking in mice at 100 mg/kg
Cell Signaling Technology Deoxyribonuclease I Recombina
Deoxyribonuclease I, Recombinant (Animal-Free, Protease and RNase Free) 1 vial
Meridian Life Science Gly-Free T4 DNA Ligase -HC, 20UL
Glycerol-Free T4 DNA Ligase (HC) a glycerol-free, high concentration enzyme (50U/uL) that catalyzes the formation of a phosphodiester bond between adjacent 5ʹ phosphate and 3′ hydroxyl groups in duplex DNA or RNA. The enzyme efficiently joins blunt and sticky-ended fragments in just 15 and 10 minutes respectively at room temperature (25C). It can be used to perform linker ligation, re-ligation of linearized plasmids and ligation of double-stranded oligonucleotides into vectors and enables rapid ligation of up to 100ng of fragments from most sources including PCR fragments, plasmids, cosmids, genomic, phage and viral DNA into prokaryotic or eukaryotic plasmid vectors and bacteriophage lambda vectors.
Carnabio Usa Inc JAK2/10UG/CATALYTIC
JAK2, Catalytic domain, Wild type, Amino Acid 826-1132, NP_004963.1, Expressed in Insect (sf21); 10microg
Cayman Chemical Hexnoyl-Coenzyme AsodIum s 1mg
A medium-chain fatty acyl CoA; the preferred acyl donor substrate for GOAT; a precursor in the biosynthesis of olivetolic acid
ABclonal Technology Topoisomerase II alpha/TOP2A
This gene encodes a DNA topoisomerase an enzyme that controls and alters the topologic states of DNA during transcription This nuclear enzyme is involved in processes such as chromosome condensation chromatid separation and the relief of torsional stress that occurs during DNA transcription and replication It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another thus altering the topology of DNA Two forms of this enzyme exist as likely products of a gene duplication event The gene encoding this form alpha is localized to chromosome 17 and the beta gene is localized to chromosome 3 The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance Reduced activity of this enzyme may also play a role in ataxia-telangiectasia
Cusabio Technology LLC Fish Catalase CAT ELISA kit
The Fish Catalase (CAT) ELISA Kit is designed for the quantitative detection of catalase (CAT) in fish serum and plasma samples using a competitive ELISA method This kit detects CAT within a broad dynamic range of 125 mU/mL to 2000 mU/mL with a sensitivity of 62 5 mU/mL ensuring precise measurement of enzyme activity The assay requires a short incubation period of 1 to 5 hours and utilizes a minimal sample volume of 50-100 L per test Optical density readings are performed at 450 nm providing reliable and reproducible results for research applications Ideal for studying oxidative stress biomarkers this kit offers a robust and efficient tool for quantifying CAT levels in aquatic species
ABclonal Technology Circle Ligase
Circle Ligase is a thermostable ATP-dependent ligase that can catalyze the self-circularization of single-stranded DNA (ssDNA)/single-stranded RNA (ssRNA) strands simultaneously possessing a 5-phosphate group and a 3-hydroxyl group in the absence of complementary sequences, with the length of single-stranded DNA (ssDNA)/single-stranded RNA (ssRNA) being greater than 15bp.
Medchemexpress LLC α-Amylase, Human Saliva | 9000-90-2 | 1 KU
α-Amylase, Human Saliva is a hydrolase enzyme isolated from human saliva. It functions by catalyzing the hydrolysis of internal α-1,4-glycosidic linkages in starch, leading to the production of compounds such as glucose and maltose. This enzyme is a valuable tool for various life science research applications, particularly in the study of starch metabolism and in research focused on developing nutraceuticals for conditions like diabetes and obesity.
- Isolated from human saliva
- Catalyzes hydrolysis of internal α-1,4-glycosidic linkages in starch
- Yields products like glucose and maltose
- Useful in life science research
- Can be used in the study of starch metabolism
- Can be used in research aimed at developing nutraceuticals for diabetes and obesity
Biotium Topoisomerase (DNA) I, Mitochondrial (TOP1MT)(TOP1MT/568), CF740 conjugate, 0.1mg/mL
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can giv
Supply Solutions Sigma Aldrich - Neuraminidase (Sialidase) f. V.cholerae * Third Party Item
Sigma Aldrich - Neuraminidase (Sialidase) f. V.cholerae * Third Party Item
Aldevron Ribonuclease Inhibitor, 2500ug
2500ug dispense of Ribonuclease Inhibitor (Rnase Inhibitor). Ribonuclease Inhibitor is a potent, noncompetitive inhibitor of pancreatic-type ribonucleases including ribonucleases A, B and C.
Cayman Chemical CISD1 CytosolIc DomaInhumn
Source: Recombinant human N-terminal His-tagged CISD1 expressed in E. coli • Amino acids: 32-108 • MW: 11.3 kDa
Cayman Chemical Coenzyme A sodium salt hydra
An essential cofactor functioning as an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism; the pantothenate kinase step of the coenzyme A biosynthetic pathway has been identified as a target for the development of antibacterial compounds
ABclonal Technology Exonuclease III (E. coli)
Exonuclease III (E.coli) catalyzes the stepwise removal of mononucleotides from 3?-hydroxyl termini of duplex DNA. The preferred substrates are dsDNA with blunt or recessed 3?-, termini although the enzyme also acts at nicks in dsDNA to produce single-strand gaps. dsDNA with 3?-overhang are resistant to cleavage; when overhangs length is ≥ 4 bases，dsDNA are able to fully prevent ExoIII cleavage process. Exonuclease III has also been reported to have RNase H, 3?-phosphatase and AP-endonuclease activities.