General Clinical Chemistry Analyzers and Accessories
Abcam SB-525334, TGFBR1 inhibitor., 25MG
MW 343.4 Da, Purity >98%. Cell permeable, potent, selective transforming growth factor beta 1 receptor (ALK5) (IC₅₀ = 14.3 nM) and ALK4 (IC₅₀ = 58.5 nM) inhibitor, with no activity at ALK2, 3 and 6 (IC₅₀ > 10 μM). Blocks fibrosis and renal injury markers in a puromycin-induced nephritis model. Causes significant attenuation in Smad2/3 nuclear translocation and a decrease in CTGF-expressing cells, myofibroblast proliferation and type 1 collagen deposition resulting in an overall attenuation in bleomycin-induced pulmonary fibrosis.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Ticagrelor, P2Y12 receptor antagonist, 10MG
MW 522.6 Da, Purity >98%. Reversible antagonist of the platelet purinergic P2Y12 receptor, the main receptor responsible for ADP-induced platelet aggregation. Changes the conformation of the P2Y12 receptor, resulting in reversible, concentration dependent inhibition of the receptor.
The product is subject to the following: Abcam Restricted Use Statement
Hach Company QP1680 High-Temperature TNb Laboratory Analyser with 65-position autosampler
The QP1680 high-temperature laboratory analyser measures total bound nitrogen (TNb) using catalytic combustion and chemiluminescence detection. It includes a 65-position autosampler for 40 mL vials and is engineered for rapid, repeatable laboratory TNb analysis across a wide concentration range.
- Measures total bound nitrogen (TNb) using chemiluminescence.
- 65-position autosampler compatible with 40 mL vials.
- Analysis time approx. 3 minutes per sample.
- Measuring range TNb 0-30,000 mg/L; LOD 20 μg/L.
- Sample volume 10-1,000 μL.
- Catalytic combustion oxidation at 720 °C; furnace max up to 1050 °C.
- Dimensions 440 x 380 x 700 mm; weight approx. 29 kg.
- Power supply 100-240 VAC, 50/60 Hz; analyser power up to 750 W.
- Meets ASTM D8083, EN 12260, ISO 11905-2, NEN-ISO 20236.
Abcam LCL161, 5MG
MW 500.6 Da, Purity >99%. Small molecule SMAC mimetic inhibitor of multiple IAP (Inhibitor of apoptosis) family proteins. (IC₅₀ = 10.23 μM). Inhibits cell proliferation and viability in two human hepatocellular carcinoma cells (Hep3B, IC₅₀ = 10, and PLC5, IC₅₀ = 19).
The product is subject to the following: Abcam Restricted Use Statement
Abcam WAY-316606, 1MG
MW 448.5 Da, Purity >=98%. A secreted Frizzled-Related Protein-1 (sFRP-1) inhibitor (IC₅₀ = 0.65 μM). It blocks sFRP-1 from interacting with Wnt and thus increases Wnt signaling.
The product is subject to the following: Abcam Restricted Use Statement
Abcam EHop-016, Rac GTPase inhibitor, 5MG
MW 430.5 Da, Purity >98%. Specific Rac GTPase inhibitor. Analog of NSC-23766 (ab142161). Approximately 100-fold more potent against Rac (IC₅₀ = 1.1 μM) than NSC-23766. Specific for Rac1 and Rac3 at concentrations of ≤5 μM. At higher concentrations (10μM) inhibits the the related Rho GTPase Cdc42. Also inhibits the activity of the Rac downstream effector p21-activated kinase (PAK), lamellipodia extension, and cell migration in metastatic cancer cells.
The product is subject to the following: Abcam Restricted Use Statement