General Clinical Chemistry Analyzers and Accessories
SHIMADZU SCIENTIFIC INS (3P ONLY) VFU2-44 FILTER F/ 4200 ANALYZR
NC3727073 VFU2-44 FILTER F/ 4200 ANALYZR
Abcam Anidulafungin, 5MG
MW 1140.2 g/mol, Purity >=95%. Inhibits fungal (1→3)-β-D-glucan synthase. Potent in vitro activity against Aspergillus and Candida species (MIC₅₀ of 0.03 to 4 μg/ml), including those resistant to fluconazole or amphotericin B. Effective in treating esophageal candidiasis in clinical trials.
The product is subject to the following: Abcam Restricted Use Statement
Abcam ML 204, TRPC4 blocker, 5MG
MW 226.32 Da. Selective TRPC4 channel blocker (IC₅₀ = 0.96 (fluorescence assay) - 2.6 μM (electrophysiological assay)). Selective versus TRPC6 (19-fold) and TRPC5 (9-fold). Essentially inactive at TRPV1, TRPV3, TRPA1 and TRPM8 channels at concentrations up to 22 μM.
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen Flumequine
Chemical. CAS 42835-25-6. Formula C14H12FNO3. MW 261.3. Synthetic. Flumequine is a fluoroquinolone synthetic chemotherapeutic antibiotic used to treat bacterial infections. Targets primarily gram negative bacteria, especially those which cause enteric infections in animals. It is used to study processes that affect mammalian chromosome and DNA unwinding at the level of gyrase/topoisomerases. It inhibits topoisomerases, which are needed for the transcription and replication of bacterial DNA. The inhibition of the topoisomerases results in strand breakage of the bacterial chromosome, supercoiling and resealing. Therefore, DNA replication and transcription is inhibited. It was also used to study hepatocarcinogenicity and DNA damage in mice and the mechanisms of quinolone resistance.
AdipoGen Triazamate
Chemical. CAS 112143-82-5. Formula C13H22N4O3S. MW 314.4. Synthetic. Insecticide, which is a plantsystemic aphicide. Inhibits acetylcholinesterase AChE. Specific to aphids. It is safe to beneficial insects and mites. Can be used as a reference compound.
AdipoGen C8-DL-HSL
Chemical. CAS 106983-30-6. Formula C12H21NO3. MW 227.3. Synthetic. N-Octanyol-DL-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones AHL are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.
Abcam 7-Cl-O-Nec1, metabolically stable RIP1 inhibitor, 25MG
MW 277.7 Da, Purity >98%. Necrostatin-1 (ab141053) analog with superior selectivity and metabolic stability in blocking RIP1. No off-target inhibition of indolamine-2,3-deoxygenase (IDO) in contrast to Necrostatin-1. Higher activity in inhibiting necroptosis in Jurkat cells than Necrostatin-1 (EC₅₀ = 210 nM vs. EC₅₀ = 490 nM).
The product is subject to the following: Abcam Restricted Use Statement