Custom Peptides
Cayman Chemical TrIpterygIumWIlforgIn 10mg
An analytical reference standard categorized as a cathinone intended for research and forensic applications
Cayman Chemical Cyclo RGDyKtrIfluoroACTAt 10mg
A PXR antagonist (IC50 0 51 UM) selective for PXR over 10 additional nuclear receptors at 5 UM as well as over a panel of 384 kinases at 10 UM inhibits rifampicin-induced PXR activation from 0 1-10 UM inhibits rifampicin-induced CYP3A4 activity in primary human hepatocytes inhibits PXR agonist-induced CYP3A4-mediated metabolism of midazolam and paclitaxel in hPXR-tg mice at 200 mg/kg
Cayman Chemical QuInaprIlat 10mg
Source Recombinant human C-terminal His-tagged VISTA expressed in HEK293 cells Amino acids 33-194 MW 19 6 kDa
Cayman Chemical Columbamn 10mg
A phospholipid a component of LDL and HDL enrichment in recombinant HDLs decreases cholesterol ester formation by LCAT in vitro
Cayman Chemical PAR21-6 amIdehumntrI 10mg
An internal standard for the quantification of ciprofibrate by GC- or LC-MS
Cayman Chemical DIchlorvos-d6 10mg
An AMPK activator (EC50 9 nM) selective for AMPK over a kinase panel at 10 UM as well as CYP3A4 and CYP2D6 (IC50s 50 UM) and PXR (EC50 30 UM) increases muscle and liver levels of phosphorylated ACC and reduces insulin resistance in DIO mice at 30 mg/kg inhibits hepatic fatty acid synthesis in db/db mice
Cayman Chemical ChebulInIc AcId 10mg
An oligosaccharide comprised of nine a-14-linked glucose molecules has been used as a substrate to study the cleavage distribution and enzyme kinetics of B. licheniformis thermostable a-amylase as well as the enzyme kinetics of A. niger glucoamylase II
Cayman Chemical Enarodustat 10mg
An iridoid glycoside with diverse biological activities reduces microvessel formation by 67 in a chick embryo chorioallantoic membrane assay at 2 g/egg inhibits LPS-induced increases in TNF-a IL-1B and IL-6 production in RAW 264.7 macrophages in a concentration-dependent manner at 20 40 and 80 mg/L reduces lung MPO activity and BALF levels of TNF-a IL-1B and IL-6 in a mouse model of LPS-induced acute lung injury at 20 40 and 80 mg/kg dietary administration decreases body weight gain WAT weight and the ratio of WAT weight to body weight in a high-fat diet-induced mouse model of metabolic syndrome
Cayman Chemical Lumateperontosylate 10mg
ABlactam antibiotic active against B. fragilis E. lentum P. morbillorum and F. nucleatum (MICs 8 4 2 and 4 Ug/ml respectively) active against 10 strains of S. faecalis at 32 Ug/ml increases survival and reduces bacteremia in a rabbit model of S. faecalis endocarditis completely eliminates lung P. morbillorum E. lentum and F. nucelatum but not B. fragilis in a rabbit model of pulmonary P. morbillorum E. lentum F. nucelatum and B. fragilis infection at 300 mg/kg
Cayman Chemical HArgGlyAspCysOHtrIfluo 10mg
A platelet aggregation inhibitor inhibits ADP- collagen- or epinephrine-induced platelet aggregation in isolated human platelets (IC50s 730 92 and 3.4 UM respectively) inhibits arachidonic acid-induced platelet aggregation and TXA2 production in isolated rat platelets (IC50s 3.3 and 32.8 UM respectively) reduces LPS-induced contractions in isolated endothelium-denuded rat aortic strips in a concentration-dependent manner decreases thrombus weight in a rat model of arterio-venous shunt thrombosis at 50 mg/kg increases survival in a mouse model of septicemia induced by LPS at 10 and 20 mg/kg
Cayman Chemical nsIrItIdeacetate 10mg
A mycotoxin induces tremors in mice and decreases the time to fall from the rotarod at 4 mg/kg reduces W. cervinata larvae weight gain and food consumption at 20 Ug/g
Cayman Chemical GYKI 52466hydrochlorIde 10mg
An internal standard for the quantification of docosapentaenoic acid methyl ester by GC- or LC-MS
Cayman Chemical TrIfolIrhIzIn 10mg
A tyrphostin that inhibits EGFR and HER2 (IC50s 12 and 4.9 M respectively for inhibition of autophosphorylation) inhibits PanK3 (IC50 3 M) inhibits EGF-dependent proliferation of HER14 cells (IC50 25 M)
Cayman Chemical GarenoxacIn 10mg
A triterpene scavenges DPPH radicals in a cell-free assay at 0.8 mM prevents arsenic-induced decreases in the activity of SOD1 catalase GST and glutathione reductase in mouse brain at 20 mg/kg for four days reduces tumor growth in an Ehrlich murine spontaneous adenocarcinoma model at 100 and 250 mg/kg for 20 days reduces cisplatin-induced renal fibrosis and increased kidney TNF-a and IL-1B levels in mice at 100 and 250 mg/kg per day for 10 days
Cayman Chemical Borusertb 10mg
A mixture of the disialogangliosides GD1a GD1b and GD3 intended for use as a reference standard for the detection of disialogangliosides in a variety of sample types by TLC LC- or GC-MS