Custom Peptides
Cayman Chemical PB22 N 5hydroxypentyl3c 10mg
A potential metabolite of PB-22; intended for forensic and research purposes
Cayman Chemical Daclatsvr 10mg
An NS5A inhibitor (Kds = 8 and 210 nM for the NS5A33-202 and NS5A26-202 residues of HCV genotype 1b, respectively); potently inhibits HCV replication in multiple HCV replicon genotypes (EC50s = 9-146 pM) with the highest potency in genotypes 1b and 4a (EC50s = 9 and 12 pM, respectively); disrupts NS5A subcellular localization when used at a concentration of 1 nM; inhibits HCV RNA synthesis and virion assembly and secretion when used at a concentration of 1 nM; inhibits OAT1B1 and OAT1B3 (IC50s = 1.5 and 3.27 µM, respectively)
Cayman Chemical EVP-6124hydrochlorIde 10mg
A partial agonist of α7 subunit-containing nAChRs (IC50 = 22.38 nM); 1,000-fold selective for α7 subunit-containing nAChRs over α4β2 subunit-containing nAChRs at 10 µM, as well as a panel of 60 peptide and nonpeptide receptors, ion channels, and transporters; induces inward currents in Xenopus oocytes expressing human α7 subunit-containing nAChRs (EC50 = 0.16 µM); reverses scopolamine-induced deficits in the novel object recognition task and prevents natural forgetting of a familiar object in rats at 0.1, 0.3, and 1 mg/kg; reduces premature responding in the 5CSRTT in low-attentive female rats
Cayman Chemical NCS-382sodIum salt 10mg
A GHBR antagonist (IC50s = 134.1 and 201.3 nM in isolated rat striatal and hippocampal membranes, respectively, in radioligand binding assays); selective for GHBR over GABA binding sites in rat brain synaptic membranes at 1 and 10 µM; decreases GHB-induced increases in inositol phosphate accumulation and cGMP levels in isolated rat hippocampal slices (IC50s = 8.6 and 30 µM, respectively); reduces GHB-induced increases in the time mice spent immobile in the forced swim test at 1.66 and 2.08 mmol/kg; decreases spike and wave discharges in audiogenic seizure-susceptible Swiss Rb mice, as well as a rat model of petit mal epilepsy, at 2.3 mmol/kg
Cayman Chemical RebaudIosIde C 10mg
A natural non-caloric sweetener; one of the predominant steviol glycosides from S. rebaudiana; metabolized by gut microbiota to steviol
Cayman Chemical 4methoxyN NDImthylcathIno 10mg
An analog of methedrone, differing by the presence of a second aminomethyl group; intended for forensic and research applications
Cayman Chemical MItomycIn C 10mg
An antitumor antibiotic that crosslinks double stranded DNA and is widely used as a tool to selectively inhibit DNA synthesis and mutagenensis, to stimulate genetic recombination, chromosome breakage and sister chromatid exchange, and to induce DNA repair
Cayman Chemical 6aMethylprednIsoLN 21hemI 10mg
A prodrug form of methylprednisolone; nanoliposomes containing 6α-methylprednisolone 21-hemisuccinate decrease disease severity in a rat model of adjuvant-induced arthritis
Cayman Chemical N-propyl-L-ArgInIn 10mg
A potent and selective competitive inhibitor of nNOS (Ki = 57 nM; bovine); exhibits 3,000-fold and 150-fold selectivity for the neuronal isoform versus the inducible (murine; Ki = 180 µM) and endothelial (bovine; Ki = 8.5 µM) isoforms of NOS, respectively
Cayman Chemical Cyclo RGDfCtrIfluoroACTAt 10mg
A cyclic pentapeptide; has been used in the synthesis of unimolecular micelles and ligand-decorated nanogels for cancer cell-targeted drug delivery
Cayman Chemical 13 14dIhdro15keto Prostag 10mg
Prominent plasma metabolite of PGF2α in the 15-hydroxy PGDH pathway
BIORTUS USA INC Human IRAK4 Protein, 100UG
Gene Name: IRAK4. Uniprot: Q9NWZ3. Construct: His-TEV-IRAK4(E154-S460 end). Expression Host: Insect cell. Purity: 90%.
Cayman Chemical 8AmInopyren1 3 6trIsulfon 10mg
An anionic fluorescent dye; ex/em spectra = 425/503 nm, respectively; forms a ground state complex with viologen-type quenchers, inducing a red-shift in the absorbance spectrum from 425 to 464 nm; pH insensitive over the pH range of 4-10; can be used in solution or immobilized through attachment of an aldehyde functionalized monomer by reductive amination; has been used as a reporter for glucose sensing and for the detection of other saccharides