Custom Peptides
Cayman Chemical CBL0137hydrochlorIde 10mg
A water soluble and metabolically stable curaxin that activates p53 with an EC50 value of 0.37 µM and inhibits NF-κB with an EC50 value of 0.47 µM; has broad anticancer activity in mice when administered orally
Cayman Chemical CPTH6hydrobromIde 10mg
A thiazole derivative that inhibits the lysine acetyltransferase activity of Gcn5 and pCAF but not p300 or CBP; blocks the acetylation of H3/H4 histones and α-tubulin in several leukemia cell lines
Cayman Chemical ChlorIsondamInIodIde 10mg
A long-lasting antagonist of nAChRs (IC50 = 1.8 µM) and ganglion blocker; decreases nicotine-induced dopamine release in rat striatal synaptosomes at concentrations ranging from 0-100 µM; a dose of 10 mg/kg blocks nicotine-induced stimulant activity for at least five weeks; prevents acquisition of conditioned taste aversion in rats when used at a dose of 5 UG, i.c.v.; inhibits autonomic ganglia when used at a dose of 50 mg/kg in cats
Cayman Chemical 13C63NItrophenylhydrazIn 10mg
A 13C-labeled derivatizing reagent for carboxylic acids
Cayman Chemical ABCHMINACA metabolIte M5A 10mg
A potential metabolite produced during metabolism of AB-CHMINACA in the liver; intended for forensic and research applications
Cayman Chemical 3 4MethylendIoxy PV9hydro 10mg
A cathinone whose physiological and toxicological properties are not known
Cayman Chemical GInkgolIde B 10mg
A potent PAFR antagonist that inhibits platelet aggregation at concentrations from 10-500 μM; demonstrates anticancer, anti-inflammatory, anti-allergic, antioxidant, and neuroprotective effects
Cayman Chemical ODesmethyl VenlafaxInd 10mg
An internal standard for the quantification of (±)-O-desmethyl venlafaxine by GC- or LC-MS; intended for research and forensic applications
Cayman Chemical Tocopherol 10mg
A form of vitamin E with antioxidant and anti-inflammatory properties; traps and detoxifies reactive nitrogen oxide species, including nitrogen dioxide, in cell-free assays; reduces PGE2 synthesis induced by LPS in RAW 264.7 macrophages and by IL-1β in A549 cells (IC50s = 7.5 and 4 μM, respectively); inhibits LPS-induced nitrite release and iNOS expression in RAW 264.7 cells at 10 μM and reduces COX-2 activity in A549 cells pretreated with IL-1β; serum levels are decreased in patients with cardiovascular disease
Cayman Chemical N6-EthyladenosIn 10mg
An adenosine A1 and A3 receptor agonist; binds selectively to rat adenosine A1 and human adenosine A3 receptors over rat adenosine A2A and A3 receptors (Kis = 4.9, 4.7, 8,900 and 1,050 nM, respectively, for the recombinant receptors in CHO cells); inhibits forskolin-induced cAMP accumulation in CHO cells expressing the human recombinant adenosine A3 receptor at 10 µM
Cayman Chemical GInsenosIde Rb1 10mg
A triterpene saponin with diverse biological activities; decreases apoptosis and increases in PKA, PKC, caspase-3, and caspase-9 levels in H9c2 rat cardiomyocytes at 100 µM; inhibits glucose-induced cytotoxicity and production of ROS in primary rat hippocampal neurons at 1 µM; inhibits LPS-induced activation of IRAK1, IΚΚβ, NF-κB, as well as the MAP kinases ERK, JNK, and p38, in mouse peritoneal lavage fluid at 100 µM; increases hippocampus nestin and GFAP levels in a rat model of Alzheimer’s disease induced by Aβ40 at 10 mg/kg for 30 days; decreases high-fat diet-induced increases in liver weight, hepatic triglyceride accumulation, serum fasting glucose levels, and serum LDL levels in a mouse model of obesity at 200 mg/kg per day
Cayman Chemical DSmethyldoxepInhydroCLOrI 10mg
The primary metabolite of the tricyclic antidepressant doxepin
Cayman Chemical bk-2C-BhydrochlorIde 10mg
A β-ketone analog of 2C-B; intended for forensic and research purposes
Cayman Chemical L-CystathIonIn 10mg
A precursor of cysteine formed in the methionine transsulfuration pathway; deficiency can indicate the presence of metabolic disorders such as cystathioninuria