Drug Discovery Research Screening Libraries
Apexbio Technology LLC DiscoveryProbe™ Bioactive Compound Library, 250uL/well(10 mM solution), 96 Well Racks With Screw Cap
3317 bioactive compounds. Other sizes are available. Please inqury us for quote.
Apexbio Technology LLC DiscoveryProbe™ Bioactive Compound Library Plus, 250uL/well(10 mM solution), 96 Well Racks With Screw Cap
DiscoveryProbe™ Bioactive Compound Library Plus is a ready-to-use chemical library used for drug discovery, lab drug screening, drug target identification, and other pharmaceutical-related applications. It is available for high-throughput screening (HTS) and high-content screening (HCS). It consists of over 4400 small molecules with validated biological and pharmacological activities. Other sizes are also available. Please inqury us for quote.
Selleck Chemical LLC MAPK Inhibitor Library 100uL/well
A unique collection of 259 small molecule inhibitors used for MAPK signaling research. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Enzo Life Sciences SCREEN-WELL Hematopoietic Toxicity library (100µl/well)
The SCREEN-WELL Hematopoietic Toxicity Library is a focused collection of 115 compounds with defined and diverse hematopoietic toxicity, including myelosuppression, neutropenia, leukopenia, anemia, and many more. A variety of structurally and mechanistically different compound classes are included, as well as nontoxic controls. The compounds are dissolved in DMSO at 10mM and aliquoted into deep-well plates. The library is an essential tool for predictive toxicology screening and assay development. Long Term Storage: -80°C. Applications: HTS .
Enzo Life Sciences SCREEN-WELL REDOX library (500 µl/well)
The SCREEN-WELL REDOX library contains 83 compounds with defined prooxidant or antioxidant activity. Compounds are dissolved in DMSO at 10mM and aliquoted into deep-well plates at 100 or 500µl per well.A variety of structurally and mechanistically different compound classes are included such as hydroperoxides, polyphenolics, metal chelators, thiols, thiol traps, radical scavengers, lazaroids and glutathione modulators as well as small molecule enzyme mimetics for SOD and glutathione peroxidase. The library is a useful tool for studying the roles of pro- and antioxidant molecules in cells as well as for use in in vitro applications. Long Term Storage: -80°C. Applications: HTS .
Enzo Life Sciences SCREEN-WELL Autophagy library (500 µl/well)
The SCREEN-WELL Autophagy library contains 94 compounds with defined autophagy-inducing or -inhibitory activity. Compounds are dissolved in DMSO or water at 10mM and aliquoted into deep-well plates at 100 or 500µl per well. A variety of structurally and mechanistically different compound classes are included. A useful tool for studying the roles of pro- and anti-autophagic molecules in cells as well as for use in in vitro applications. Long Term Storage: -80°C. Applications: HTS .
Selleck Chemical LLC Apoptosis Compound Library 100uL/well
A unique collection of 1099 small molecules used for apoptosis research targeting Bcl-2,Caspase,p53,TNF-alpha,Mdm2,survivin, etc. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
AdipoGen 2-Fluoro-2-deoxy-D-glucose
Chemical. CAS 29702-43-0. Formula C6H11FO5. MW 182.15. 2-Fluoro-2-deoxy-D-glucose is a glucose analog that inhibits cellular glycosylation. It is the natural isotope-form of 18F-FDG that can be taken up by cells but does not undergo metabolic glycolysis. FDG uptake is closely related to the expression of the glucose transporter GLUT in malignant tumours. FDG is also a substrate of hexokinase isozymes and an inhibitor of cellular glycosylation. FDG is taken up by high-glucose-using cells such as brain, brown adipocytes, kidney and cancer cells, where phosphorylation prevents the glucose from being released again from the cell, once it has been absorbed. The 2-hydroxyl group –OH in normal glucose is needed for further glycolysis metabolism of glucose by splitting it, but FDG is missing this 2-hydroxyl and cannot be further metabolized in cells. FDG is used in positron emission tomography PET as contrast agent and is the most widely used PET marker. FDG-PET can be used fo
AdipoGen 2-Fluoro-2-deoxy-D-glucose
Chemical. CAS 29702-43-0. Formula C6H11FO5. MW 182.15. 2-Fluoro-2-deoxy-D-glucose is a glucose analog that inhibits cellular glycosylation. It is the natural isotope-form of 18F-FDG that can be taken up by cells but does not undergo metabolic glycolysis. FDG uptake is closely related to the expression of the glucose transporter GLUT in malignant tumours. FDG is also a substrate of hexokinase isozymes and an inhibitor of cellular glycosylation. FDG is taken up by high-glucose-using cells such as brain, brown adipocytes, kidney and cancer cells, where phosphorylation prevents the glucose from being released again from the cell, once it has been absorbed. The 2-hydroxyl group –OH in normal glucose is needed for further glycolysis metabolism of glucose by splitting it, but FDG is missing this 2-hydroxyl and cannot be further metabolized in cells. FDG is used in positron emission tomography PET as contrast agent and is the most widely used PET marker. FDG-PET can be used fo
AdipoGen R-3-Hydroxymyristic acid
Chemical. CAS 28715-21-1. Formula C14H28O3. MW 244.4. Synthetic. Hydroxy fatty acid used to study its role in biological processes such as oxidative stress, inflammation and insulin resistance. Used in endotoxin and lipid A research, since it is one of two major components of bacterial Lipid A. Shows antifungal activity. Compound could be used as analytical reference in assaying food samples.
AdipoGen Benzokfluoranthene
Chemical. CAS 207-08-9. Formula C20H12. Molecular Weight 252.31. Benzokfluoranthene is an optical sensor for nitro-aromatic compounds, chosen due to fluorescence quenching of the molecule see Reference 2. Polycyclic aromatic hydrocarbon PAH compound. Benzokfluoranthene is primarily found in gasoline exhaust, cigarette smoke, coal tar, coal and oil combustion emissions, lubricating oils, used motor oils and crude oils and is consdered a contaminant. This compound could be used as reference material.