Nucleotides
Cayman Chemical NIcotInamIde rIbosIdechlorI 5g
A riboside form of nicotinamide; a precursor of NAD+ and a source of vitamin B3; increases intracellular and mitochondrial NAD+ content in C2C12, Hepa1.6, and HEK293 cells in a concentration-dependent manner at concentrations ranging from 1-1,000 μM; decreases acetylation of FOXO1 and SOD2 but not tubulin; increases NAD+ levels in liver and skeletal muscle and prevents body weight gain in mice fed a high-fat diet when used at a dose of 400 mg/kg per day; increases NAD+ in the cerebral cortex and reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease
ABclonal Technology Cullin 3 Rabbit pAb
This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Cayman Chemical AdenosIn 5-dIphosphate 1g
A central component of energy storage, metabolism, and signal transduction in vivo; a precursor for ATP and agonist of purinergic receptors
eMolecules Uridine-5'-triphosphate disodium salt | 285978-18-9 | MFCD11101450 | 5g
Combi-Blocks | Uridine-5'-triphosphate disodium salt | 5g | 517031671 | QB-2953 | 95.000 | 285978-18-9 | MFCD11101450 | 528.103 | C9H13N2Na2O15P3
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Apexbio Technology LLC 5-Br-UTP(Synonyms: 5-Bromo-UTP, 5-Br-uridine triphosphate, 5-Bromo-uridine 5'-triphosphate, 5-Br-U 5'-triphosphate), 50ul (100 mM).
5-Br-UTP is a chemically modified ribonucleoside triphosphate that incorporates a bromine substituent at the 5 position of uracil Upon enzymatic incorporation into RNA sequences this compound confers enhanced structural stability and tolerance to enzymatic degradation by nucleases Such modified ribonucleotides are frequently employed in SELEX (Systematic Evolution of Ligands by EXponential enrichment) methodologies to generate aptamers exhibiting improved resistance to nucleolytic cleavage and greater thermal robustness Consequently 5-Br-UTP holds relevance for RNA-based therapeutic research and aptamer engineering applications
Trilink Bio Technologies Inc N1-Methyl-pseudouridine 5'-triphosphate
N1-Methylpseudouridine 5'-Triphosphate is a modified nucleoside triphosphate used in RNA research and synthesis. It contains a methyl group on the N1 position of the pseudouridine nucleobase. This analog is cell permeable and can be incorporated into RNA by polymerases. It is supplied as a lithium salt at ≥95% purity by TriLink BioTechnologies. The product has a molecular weight of 491.15 g/mol and is soluble up to 100 mM in water or buffer. It can be used to study RNA structure and function.
Revvity Health Sciences Inc AlphaLISA KRAS WT / GTP Binding Kit, 5,000 Assay Points
AlphaLISA KRAS WT / GTP Binding Kit, 5,000 Assay Points
Apexbio Technology LLC N1-Methylpseudo-UTP (D3) 100ul (100 mM)
N1-Methylpseudo-UTP D3 is a chemically modified nucleotide analog labeled with deuterium It is designed to substitute conventional uridine triphosphate during enzymatic transcription reactions allowing for the synthesis of isotope-labeled RNA N1-Methylpseudo-UTP D3 exerts its function through incorporation into RNA thereby conferring distinct structural and biochemical properties to RNA transcripts Based on these properties N1-Methylpseudo-UTP D3 holds research potential in structural analyses of RNA RNA-protein interaction studies and biophysical investigations including nuclear magnetic resonance (NMR) spectroscopy