Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Tocris Bioscience™ ESI 1
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Selective HDAC3 inhibitor; also myelination inducer
| Target | Class I Histone Deacetylases Inhibitors |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-(2-Aminophenyl)-5-[(phenylmethyl)amino]-2-pyrazinecarboxamide dihydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C18H17N5O.2HCl |
Tocris Bioscience™ HX 531
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CAS: 188844-34-0 Molecular Formula: C29H29N3O4
| CAS | 188844-34-0 |
|---|---|
| Molecular Formula | C29H29N3O4 |
Tocris Bioscience™ VU 0364739 hydrochloride
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CAS: 1244640-48-9 Molecular Formula: C26H28ClFN4O2
| CAS | 1244640-48-9 |
|---|---|
| Molecular Formula | C26H28ClFN4O2 |
Tocris Bioscience™ C 75
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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CAS: 191282-48-1 Molecular Formula: C14H22O4
| CAS | 191282-48-1 |
|---|---|
| Molecular Formula | C14H22O4 |
Tocris Bioscience™ DMSO, Cell Cryopreserve Grade
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Intracellular cryoprotective agent
Tocris Bioscience™ Sertraline hydrochloride
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CAS: 79559-97-0 Molecular Formula: C17H18Cl3N
| CAS | 79559-97-0 |
|---|---|
| Molecular Formula | C17H18Cl3N |
Tocris Bioscience™ Medetomidine hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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CAS: 86347-15-1 Molecular Formula: C13H17ClN2
| CAS | 86347-15-1 |
|---|---|
| Molecular Formula | C13H17ClN2 |
Tocris Bioscience™ SJPYT 310
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Potent and selective PXR antagonist
| Target | PXR/NR1I2 |
|---|---|
| CAS | 2883814-84-2 |
| Purity | 98% |
| Chemical Name or Material | N-[5-(1,1-Dimethylethyl)-2-[(1S)-1-methylbutoxy]phenyl]-1-(2-methoxy-5-methylphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C27H36N4O3 |
Tocris Bioscience™ HU 308
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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CAS: 256934-39-1 Molecular Formula: C27H42O3
| CAS | 256934-39-1 |
|---|---|
| Molecular Formula | C27H42O3 |
Tocris Bioscience™ MRS 2905
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Potent and selective P2Y14 receptor agonist
Tocris Bioscience™ Givinostat hydrochloride
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Histone deacetylase inhibitor
| CAS | 199657-29-9 |
|---|---|
| Chemical Name or Material | [6-[(Diethylamino)methyl]-2-naphthalenyl]methyl-N-[4-[(hydroxyamino)carbonyl]phenyl]carbamate hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C24H27N3O4.HCl |
| Formula Weight | Observed MW: 457.95 |
| Assay Percent Range | >98% |
Tocris Bioscience™ CC4
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Small and Specialty Supplier Partner
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High affinity and subtype-selective α6β2 and α4β2 nAChR partial agonist
| Target | Additional Nicotinic (a4b2) Receptor Compounds |
|---|---|
| CAS | 492-02-4 |
| Purity | >98% |
| Chemical Name or Material | (1R,5S)-1,2,3,4,5,6-Hexahydro-3-[2-[(1R,5S)-1,5,6,8-tetrahydro-8-oxo-1,5-methano-2H-pyrido[1,2-a][1,5]diazocin-3(4H)-yl]ethyl]-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C24H30N4O2 |
| Formula Weight | 406.52 |
Tocris Bioscience™ RO-3
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CAS: 1026582-88-6 Molecular Formula: C16H22N4O2
| CAS | 1026582-88-6 |
|---|---|
| Molecular Formula | C16H22N4O2 |
Tocris Bioscience™ N6-Cyclopentyladenosine
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CAS: 41552-82-3 Molecular Formula: C15H21N5O4
| CAS | 41552-82-3 |
|---|---|
| Molecular Formula | C15H21N5O4 |
Tocris Bioscience™ TC-G 1005
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Potent and selective GPBA receptor (TGR5) agonist
| CAS | 1415407-60-1 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 100mM in DMSO and to 100mM in ethanol |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | TC-G 1005 |
| Recommended Storage | Store at -20°C |
| Synonym | (4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone |
| Molecular Formula | C25H25N3O2 |
| Formula Weight | 399.48 |