Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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1,771
Tocris Bioscience™ Janelia Fluor 635, SE
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Red dye (Reactive group: NHS ester). Applications: super resolution microscopy, confocal, flow and live cell imaging
1,772
Tocris Bioscience™ Phentolamine Mesylate
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Adrenergic α receptor antagonist; antihypertensive
1,773
Tocris Bioscience™ Yhhu 3792
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Notch signaling pathway activator; enhances the self-renewal capability of NSCs; active in vivo
1,774
Tocris Bioscience™ AP 20187
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Chemical inducer of protein dimerization; active in vivo
1,775
Tocris Bioscience™ SAG dihydrochloride
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Dihydrochloride salt of SAG; Smo receptor agonist
| CAS | 2702366-44-5 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide dihydrochloride |
| Recommended Storage | Store at -20°C |
| Formula Weight | Observed MW: 562.98 |
| Assay Percent Range | >99% |
1,776
Tocris Bioscience™ Clozapine N-oxide dihydrochloride
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Activator of muscarinic DREADDs; water soluble version of Clozapine N-oxide (Cat. No. 4936)
| Target | DREADD Activators |
|---|---|
| CAS | 2250025-93-3 |
| Purity | 99% |
| Chemical Name or Material | 8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5 H-dibenzo[b,e][1,4 ]diazepine dihydrochloride |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C18H19ClN4O0.2 HCl |
| Formula Weight | Observed MW: 415.74 |
| Assay Percent Range | >99% |
1,777
Tocris Bioscience™ DIM-C-pPhOH
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Nur77 antagonist
| CAS | 151358-47-3 |
|---|---|
| Chemical Name or Material | 1,1-Bis(3'-indolyl)-1-(p-hydroxyphenyl)methane |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C23H18N2O |
| Formula Weight | Observed MW: 338.408 |
| Assay Percent Range | >98% |
1,778
Tocris Bioscience™ NVP 2
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Potent and selective ATP-competitive CDK9 inhibitor
1,779
Tocris Bioscience™ Isoproterenol hydrochloride
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CAS: 51-30-9 Molecular Formula: C11H18ClNO3
| CAS | 51-30-9 |
|---|---|
| Molecular Formula | C11H18ClNO3 |
1,780
Tocris Bioscience™ BRD 73954
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Dual histone deacetylase (HDAC) 6/8 inhibitor
| CAS | 1440209-96-0 |
|---|---|
| Chemical Name or Material | N1-Hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C16H16N2O3 |
| Formula Weight | Observed MW: 284.31 |
| Assay Percent Range | >98% |
1,781
Tocris Bioscience™ ASB 14780
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Potent and selective cytosolic phospholipase A2 alpha (cPLA2α) inhibitor; active in vivo; orally bioavailable
1,782
Tocris Bioscience™ PD 407824
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CAS: 622864-54-4 Molecular Formula: C20H12N2O3
| CAS | 622864-54-4 |
|---|---|
| Molecular Formula | C20H12N2O3 |
1,783
Tocris Bioscience™ THIP hydrochloride
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CAS: 85118-33-8 Molecular Formula: C6H9ClN2O2
| CAS | 85118-33-8 |
|---|---|
| Molecular Formula | C6H9ClN2O2 |
1,784
Tocris Bioscience™ AM 580
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CAS: 102121-60-8 Molecular Formula: C22H25NO3
| CAS | 102121-60-8 |
|---|---|
| Molecular Formula | C22H25NO3 |
1,785
Tocris Bioscience™ SNC 80
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CAS: 156727-74-1 Molecular Formula: C28H39N3O2
| CAS | 156727-74-1 |
|---|---|
| Molecular Formula | C28H39N3O2 |