Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Tocris Bioscience™ U0126
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CAS: 109511-58-2 Molecular Formula: C18H16N6S2
| CAS | 109511-58-2 |
|---|---|
| Molecular Formula | C18H16N6S2 |
Tocris Bioscience™ Bax channel blocker
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Allosteric inhibitor of Bax channel activation
| Inhibitors | Bax channel blocker |
|---|---|
| Product Type | Bax channel blocker |
| Molecular Weight (g/mol) | 540.12 |
| Purity | >98% |
Tocris Bioscience™ 5-Azacytidine
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CAS: 320-67-2 Molecular Formula: C8H12N4O5
| CAS | 320-67-2 |
|---|---|
| Molecular Formula | C8H12N4O5 |
Tocris Bioscience™ Vatalanib succinate
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Potent VEGFR inhibitor; also aromatase inhibitor
| Target | VEGF Receptor Inhibitors |
|---|---|
| CAS | 212142-18-2 |
| Purity | >99% |
| Chemical Name or Material | N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine succinate |
| Recommended Storage | Store at -20°C |
| Synonym | CGP 79787D, PTK787/ZK222584 |
| Molecular Formula | C20H15ClN4.C4H6O4 |
| Formula Weight | 464.9 |
Tocris Bioscience™ VU 0650991
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Non-competitive GLP-1 antagonist; orally bioavailable and brain penetrant
| Product Type | Antagonist |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C16H11ClF6N4O2 |
| Formula Weight | 440.73 |
Tocris Bioscience™ AC 5216
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Selective TSPO ligand
| Inhibitors | AC 5216 |
|---|---|
| Product Type | AC 5216 |
| Molecular Weight (g/mol) | 401.46 |
| Purity | >98% |
Tocris Bioscience™ UBP 310
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GluK1-selective kainate antagonist
| Inhibitors | UBP 310 |
|---|---|
| Product Type | UBP 310 |
| Molecular Weight (g/mol) | 353.35 |
| Purity | >98% |
Tocris Bioscience™ CH 223191
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CAS: 301326-22-7 Molecular Formula: C19H19N5O
| CAS | 301326-22-7 |
|---|---|
| Molecular Formula | C19H19N5O |
Tocris Bioscience™ QX 314 chloride
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CAS: 1-4-5370 Molecular Formula: C11H18ClNO
| CAS | 1-4-5370 |
|---|---|
| Molecular Formula | C11H18ClNO |
Tocris Bioscience™ Bz 423
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ATP synthase inhibitor; proapoptotic
| CAS | 216691-95-1 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Color | White |
| Solubility | Soluble to 100mM in DMSO and to 100mM in ethanol |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | 7-Chloro-1,3-dihydro-5-(4-hydroxyphenyl)-1-methyl-3-(2-naphthalenylmethyl)-2H-1,4-benzodiazepin-2-one |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C27H21ClN2O2 |
| Formula Weight | 440.92 |
Tocris Bioscience™ CP 93129 dihydrochloride
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CAS: 879089-64-2 Molecular Formula: C12H17Cl2N3O2
| CAS | 879089-64-2 |
|---|---|
| Molecular Formula | C12H17Cl2N3O2 |
Tocris Bioscience™ L-DOPA
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CAS: 59-92-7 Molecular Formula: C9H11NO4
| CAS | 59-92-7 |
|---|---|
| Molecular Formula | C9H11NO4 |
Tocris Bioscience™ DFHO
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Mimic of RFP fluorophore for imaging RNA in living cells
Tocris Bioscience™ CGP 74514 dihydrochloride
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Potent cdk1 inhibitor
| Target | Cyclin-dependent Kinase Inhibitors |
|---|---|
| Purity | >98% |
| Chemical Name or Material | rel-N2-[(1R,2S)-2-Aminocyclohexyl]-N6-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine dihydrochloride |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C19H24ClN7.2HCl |
| Formula Weight | 458.82 |
Tocris Bioscience™ AMBMP Hydrochloride, >98%
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CAS: 2095432-75-8 Molecular Formula: C19H19ClN4O3
| CAS | 2095432-75-8 |
|---|---|
| Molecular Formula | C19H19ClN4O3 |