Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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256
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270
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60,533
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257
R&D Systems™ MitoBrilliant Live 646
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Red fluorescent mitochondrial stain for live cells, Δψm dependent
| Target | Mitochondria Dyes and Probes |
|---|---|
| Recommended Storage | Store at -20°C |
258
R&D Systems™ CDK8/19i
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent and selective CDK8 and CDK19 inhibitor; maintains pluripotency of mouse PSCs in culture
| Target | Cyclin-dependent Kinase Inhibitors |
|---|---|
| CAS | 923596-52-5 |
| Purity | 0.98 |
| Chemical Name or Material | N-Propyl-3-(4-pyridinyl)imidazo[1,2-b]pyridazin-6-amine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C14H15N5 |
259
R&D Systems™ Janelia Fluor 525, Maleimide
A Tocris product, part of R&D Systems. Yellow dye (Reactive group: maleimide). Application: flow cytometry, confocal microscopy, super resolution microscopy including dSTORM & STED. Suitable for live cell imaging
260
R&D Systems™ CU CPT 9a
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent TLR8 inhibitor
| CAS | 2165340-32-7 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2-Methyl-4-(7-methoxy-4-quinolinyl)phenol |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C17H15NO2 |
261
R&D Systems™ TL 12-186
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Multikinase Degrader (PROTAC™)
262
R&D Systems™ VH 032 amide-alkylC2-acid
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. VHL ligand with alkyl linker and terminal acid for onward chemistry
263
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Thermo Scientific Chemicals Besifloxacin hydrochloride
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Thermo Scientific Chemicals Besifloxacin hydrochloride
CAS: 405165-61-9 Molecular Formula: C19H21ClFN3O3·HCl
| CAS | 405165-61-9 |
|---|---|
| Molecular Formula | C19H21ClFN3O3·HCl |
264
R&D Systems™ GSK 583
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent RIP2 kinase inhibitor; orally bioavailable and cell permeable
| CAS | 1346547-00-9 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 6-[(1,1-Dimethylethyl)sulfonyl]-N-(5-fluoro-1H-indazol-3-yl)-4-quinolinamine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H19FN4O2S |
265
R&D Systems™ AKT Inhibitor IV
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Promotes Akt hyperphosphorylation; decreases phosphorylation of Akt substrates
266
R&D Systems™ GSK 626616
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent and selective DYRK inhibitor; orally bioavailable.
| CAS | 1025821-33-3 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | (5Z)-2-[(2,6-Dichlorophenyl)amino]-5-(6-quinoxalinylmethylene)-4(5H)-thiazolone |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C18H10Cl2N4OS |
| Formula Weight | 401.27 |
267
R&D Systems™ TRPC6-PAM-C20
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Selective TRPC6 positive allosteric modulator
| CAS | 667427-75-0 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 3-(3-,4-Dihydro-6,7-dimethoxy-3,3-dimethyl-1-isoquinolinyl)-2H-1-benzopyran-2-one |
| Molecular Formula | C22H21NO4 |
268
R&D Systems™ CRT 0105950
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent LIMK1/2 inhibitor
269
R&D Systems™ AZ 12799734
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent TGF-βRI inhibitor
| CAS | 1117684-36-2 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 4-[[4-[(2.6-Dimethyl-3-pyridinyl)oxy]-2-pyridinyl]amino]benzenesulfonamide |
| Molecular Formula | C18H18N4O3S |
270
R&D Systems™ Tazemetostat
A Tocris product, part of R&D Systems. Potent and selective EZH2 inhibitor
| Target | EZH2 Inhibitor |
|---|---|
| CAS | 1403254-99-8 |
| Purity | 0.97 |
| Chemical Name or Material | N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-5-[ethyl(tetrahydro-2H-pyran-4-yl)amino]-4-methyl-4'-(4-morpholinylmethyl)[1,1'-biphenyl]-3-carboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C34H44N4O4 |