Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Tocris Bioscience™ MTEP hydrochloride
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Potent and selective mGlu5 antagonist
| CAS | 1186195-60-7 |
|---|---|
| Chemical Name or Material | 3-((2-Methyl-1,3-thiazol-4-yl)ethynyl)pyridine hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C11H8N2S.HCl |
| Formula Weight | Observed MW: 236.72 |
| Assay Percent Range | >99% |
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Tocris Bioscience™ Dexamethasone
Tocris Bioscience™ Dexamethasone
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CAS: 50-02-2 Molecular Formula: C22H29FO5
| CAS | 50-02-2 |
|---|---|
| Molecular Formula | C22H29FO5 |
Tocris Bioscience™ Picrotoxin
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CAS: 124-87-8 Molecular Formula: C30H34O13
| CAS | 124-87-8 |
|---|---|
| Molecular Formula | C30H34O13 |
Tocris Bioscience™ Quercetin
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CAS: 117-39-5 Molecular Formula: C15H10O7
| CAS | 117-39-5 |
|---|---|
| Molecular Formula | C15H10O7 |
Tocris Bioscience™ Y-27632 dihydrochloride
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CAS: 129830-38-2 Molecular Formula: C14H23Cl2N3O
| CAS | 129830-38-2 |
|---|---|
| Molecular Formula | C14H23Cl2N3O |
Tocris Bioscience™ CNV Dopamine
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Caged dopamine; photolysed by UV light
Tocris Bioscience™ PF 06424439
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Potent and selective DGAT2 inhibitor
Tocris Bioscience™ VU 0650991
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Non-competitive GLP-1 antagonist; orally bioavailable and brain penetrant
| Product Type | Antagonist |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C16H11ClF6N4O2 |
| Formula Weight | 440.73 |
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Tocris Bioscience™ Lenalidomide
Tocris Bioscience™ Lenalidomide
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CAS: 191732-72-6 Molecular Formula: C13H13N3O3
| CAS | 191732-72-6 |
|---|---|
| Molecular Formula | C13H13N3O3 |
Tocris Bioscience™ Phosphoramidon disodium salt
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Neutral endopeptidase and endothelin converting enzyme inhibitor
Tocris Bioscience™ CD38 inhibitor
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Potent CD38 inhibitor; active in vivo
Tocris Bioscience™ A 485
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Histone Acetyltransferase Inhibitors
| CAS | 1889279-16-6 |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Synonym | (1R)-N-[(4-Fluorophenyl)methyl]-2,3-dihydro-5-[[(methylamino)carbonyl]amino]-2′,4′-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[1H-indene-1,5′-oxazolidine]-3′-acetamide |
| Molecular Formula | C25H24F4N4O5 |
| Formula Weight | 536.48 |
Tocris Bioscience™ Takinib
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Potent and selective TAK1/MAP3K7 kinase inhibitor
| Target | Other Kinase Inhibitors |
|---|---|
| CAS | 1111556-37-6 |
| Purity | 0.98 |
| Chemical Name or Material | N1-(1-Propyl-1 H-benzimidazol-2-yl)-1,3-benzenedicarboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C18H18N4O2 |
Tocris Bioscience™ DFHO
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Mimic of RFP fluorophore for imaging RNA in living cells
Tocris Bioscience™ ABX 464
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HIV RNA splicing modulator
| Target | DNA, RNA and Protein Synthesis Compounds |
|---|---|
| CAS | 1258453-75-6 |
| Purity | 0.98 |
| Chemical Name or Material | 8-Chloro-N-[4-(trifluoromethoxy)phenyl]-2-quinolinamine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C16H10ClF3N2O |