Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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736
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750
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736
Tocris Bioscience™ 3-Bromopyruvate
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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MCT1 inhibitor; also inhibits hexokinase II
737
Tocris Bioscience™ RNA Imaging Probe 1c
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Fluorogenic RNA imaging probe
738
Tocris Bioscience™ DSPC
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Neutral phospholipid; component of lipid nanoparticles (LNPs)
739
Tocris Bioscience™ L-Azidonorleucine hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Unnatural Amino Acids
740
Tocris Bioscience™ NX 5948
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Potent and selective BTK Degrader (PROTAC™)
741
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Thermo Scientific Chemicals Gemifloxacin mesylate
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Thermo Scientific Chemicals Gemifloxacin mesylate
CAS: 210353-53-0 Molecular Formula: C19H24FN5O7S
| CAS | 210353-53-0 |
|---|---|
| Molecular Formula | C19H24FN5O7S |
742
Tocris Bioscience™ Jedi2
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Piezo1 channel activator
| CAS | 651005-90-2 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2-Methyl-5-(2-thienyl)-3-furancarboxylic acid |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C10H8O3S |
| Formula Weight | 208.23 |
743
Tocris Bioscience™ VH 101 phenol-alkylC6-amine
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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VHL ligand with alkyl linker and terminal amine for onward chemistry
744
Tocris Bioscience™ GSK 2795039
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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NADPH oxidase 2 (NOX2) inhibitor
| Target | NADPH Oxidase Inhibitors |
|---|---|
| CAS | 1415925-18-6 |
| Purity | 0.98 |
| Chemical Name or Material | N-[3-(2,3-Dihydro-1-methyl-1 H-indol-6-yl)-1-(1-methylethyl)-1 H-pyrrolo[2,3-b]pyridin-4-yl]-1-methyl-1 H-pyrazole-3-sulfonamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C23H26N6O2S |
745
Tocris Bioscience™ JHU 37160
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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High affinity and highly potent hM3Dq and hM4Di DREADD agonist; blood brain barrier penetrant
| Target | DREADD Activators |
|---|---|
| CAS | 2369979-68-8 |
| Purity | 0.98 |
| Chemical Name or Material | 8-Chloro-11-(4-ethylpiperazin-1-yl)-4-fluoro-5 H-dibenzo[b,e][1,4 ]diazepine |
| Recommended Storage | Store at RT |
| Molecular Formula | C19H20ClFN4 |
746
Tocris Bioscience™ LSN 3318839
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Glucagon-like peptide-1 receptor (GLP1-R) positive allosteric modulator
747
Tocris Bioscience™ dTAG Janelia Fluor™ 525
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Fluorogenic srTAG probe for live cell imaging of FBKP12 (F36V/L) labeled proteins
748
Tocris Bioscience™ YKL 5-124
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Potent and selective CDK7 inhibitor; induces cell cycle arrest
749
Tocris Bioscience™ Erlotinib Hydrochloride
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Potent, reversible EGFR tyrosine kinase inhibitor
750
Tocris Bioscience™ CeMMEC1
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Greener Choice
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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TAF1 inhibitor
| Target | Bromodomain Inhibitors |
|---|---|
| CAS | 440662-09-9 |
| Purity | 0.98 |
| Chemical Name or Material | N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,2-dihydro-2-methyl-1-oxo-4-isoquinolinecarboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H16N2O4 |