Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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736
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750
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64,752
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739
Tocris Bioscience™ UCL 1684
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 199934-16-2 Molecular Formula: C34H30Br2N4
| CAS | 199934-16-2 |
|---|---|
| Molecular Formula | C34H30Br2N4 |
740
Thermo Scientific Chemicals CGI1746, 95%
CAS: 910232-84-7 Molecular Formula: C34H37N5O4 Molecular Weight (g/mol): 579.70 InChI Key: JIFCFQDXHMUPGP-UHFFFAOYSA-N IUPAC Name: 4-tert-butyl-N-[2-methyl-3-(4-methyl-6-{[4-(morpholine-4-carbonyl)phenyl]amino}-5-oxo-4,5-dihydropyrazin-2-yl)phenyl]benzamide SMILES: CN1C=C(N=C(NC2=CC=C(C=C2)C(=O)N2CCOCC2)C1=O)C1=C(C)C(NC(=O)C2=CC=C(C=C2)C(C)(C)C)=CC=C1
| CAS | 910232-84-7 |
|---|---|
| Molecular Weight (g/mol) | 579.70 |
| SMILES | CN1C=C(N=C(NC2=CC=C(C=C2)C(=O)N2CCOCC2)C1=O)C1=C(C)C(NC(=O)C2=CC=C(C=C2)C(C)(C)C)=CC=C1 |
| IUPAC Name | 4-tert-butyl-N-[2-methyl-3-(4-methyl-6-{[4-(morpholine-4-carbonyl)phenyl]amino}-5-oxo-4,5-dihydropyrazin-2-yl)phenyl]benzamide |
| InChI Key | JIFCFQDXHMUPGP-UHFFFAOYSA-N |
| Molecular Formula | C34H37N5O4 |
742
Tocris Bioscience™ Pomalidomide 4'-PEG5-azide
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Cereblon ligand with PEG linker and terminal azide for onward chemistry
743
Tocris Bioscience™ Rf470DL
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Blue rotor-fluorogenic fluorescent D-amino acid for labeling peptidoglycans in live bacteria
744
Tocris Bioscience™ BI dihydrochloride BI hydrochloride BI hydrochloride
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Greener Choice
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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DFHBI derivative for imaging of RNA in living cells that bind Broccoli aptamers
745
Tocris Bioscience™ MitoBrilliant Live 646
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Red fluorescent mitochondrial stain for live cells, Δψm dependent
| Target | Mitochondria Dyes and Probes |
|---|---|
| Recommended Storage | Store at -20°C |
746
Tocris Bioscience™ Pomalidomide 4'-alkylC6-acid
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Cereblon ligand with alkyl linker and terminal acid for onward chemistry
747
Tocris Bioscience™ FAK Inhibitor 14
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 4506-66-5 Molecular Formula: C6H14Cl4N4
| CAS | 4506-66-5 |
|---|---|
| Molecular Formula | C6H14Cl4N4 |
749
Tocris Bioscience™ EED 226
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective EED inhibitor
| Target | EED |
|---|---|
| CAS | 2083627-02-3 |
| Chemical Name or Material | N-(2-Furanylmethyl)-8-[4-(methylsulfonyl)phenyl]-1,2,4-triazolo[4,3-c]pyrimidin-5-amine |
| Recommended Storage | Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date. |
| Molecular Formula | C17H15N5O3S |
750
Tocris Bioscience™ Opicapone
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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COMT inhibitor
| Target | Catechol O-Methyltransferase (COMT) Inhibitors |
|---|---|
| CAS | 923287-50-7 |
| Purity | 0.98 |
| Chemical Name or Material | 5-[3-(2,5-Dichloro-4,6-dimethyl-1-oxido-3-pyridinyl)-1,2,4-oxadiazol-5-yl]-3-nitro-1,2-benzenediol |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C15H10Cl2N4O6 |