Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.

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7,486 – 7,500 of 60,533 results

7,486

Cayman Chemical MTEP (hydrochloride), Purity: ≥98%, 5 mg

A negative allosteric modulator of the mGlu5a receptor subtype (Ki = 42 nM; IC50 = 110 nM); produces antidepressant, and anxiolytic effects

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7,487

Cayman Chemical PD 153035 (hydrochloride), Purity: ≥98%, CAS: 183322-45-4, 5 mg

A highly potent, reversible inhibitor of the EGFR (Ki = 5.2 pM; IC50 = 29 pM); rapidly suppresses autophosphorylation of EGFR in ﬁbroblasts and human epidermoid carcinoma cells

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7,488

Cayman Chemical ANTIBODY MDL 29951 500ug

An antagonist of NMDA receptors with high affinity for the glycine binding site (Ki = 140 nM) that is functional both in vitro and in vivo; also an agonist of GPR17 (EC50 values range from 7 nM to 6 µM, depending on the assay)

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7,489

Medchemexpress LLC HY-13030 10mg , (+)-JQ-1 CAS:1268524-70-4 Purity:>98%

HY-13030 10mg (+)-JQ-1 CAS: 1268524-70-4 (+)-JQ-1 (JQ1) is a potent, specific, and reversible BET bromodomain inhibitor, with IC50s of 77 and 33 nM for the first and second bromodomain (BRD4(1/2)). (+)-JQ-1 also activates autophagy. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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7,490

Medchemexpress LLC 4-[6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | 1206711-16-1 | 99.9% | 1 ML

DMH-1 is a selective small-molecule inhibitor of bone morphogenetic protein (BMP) type I receptors used in cell signaling and developmental biology research. It is supplied as a 10 mM solution in DMSO (1 mL) for in vitro assays.

Potent BMP type I receptor inhibitor; IC50s: ALK1 27 nM, ALK2 107.9 nM, ALK3 <5 nM, ALK6 47.6 nM.
Supplied as a 10 mM solution in DMSO, 1 mL vial.
High purity suitable for research (reported ~99.9% by HPLC).
Molecular formula C24H20N4O, molecular weight 380.44 g/mol.
Intended for cell-based and biochemical assays probing BMP signaling.

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7,491

Enzo Life Sciences Y27632 . dihydrochloride, (5mg), CAS Number: 129830-38-2

ROCK inhibitor. Y-27632 is a highly potent, cell permeable, selective and ATP competitive inhibitor of ROCK1 and ROCK2 (IC. .There has been a growing interest in Y-27632 for use in stem cell self-renewal and reprogramming. It is known to increase the survival rate of human embryonic stem cells undergoing cryopreservation. Alternative Name: (R)-(+)-trans-N-(4-Pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide . 2HCl. Formula: C14H21N3O . 2HCl. MW: 247.3 . 73.0. CAS Number: 129830-38-2. Purity: ≥98% (HPLC (UV)). Appearance: White to pale yellow powder. Solubility: Soluble in DMSO (25mg/ml), methanol (25mg/ml), acetonitrile (<1mg/ml), dioxan (<1mg/ml), water (very soluble). Use/Stability: Stock solutions are stable for up to 1 month when stored at -20°C. Long Term Storage: -20°C

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7,492

Medchemexpress LLC HY-50904 50mg , Nintedanib CAS:656247-17-5 Purity:>98%

HY-50904 50mg Nintedanib CAS: 656247-17-5 Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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7,493

Ambeed DIMETHYL FUMARATE-100G

Dimethyl fumarate, 100G, CAS# 624-49-7, MFCD00064438, MOLWT: 144.13

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7,494

SELLECK CHEMICAL LLC CISPLATIN 10MG

NC2594447 CISPLATIN 10MG

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7,495

Selleck Chemical LLC Colforsin (Forskolin) 10mg 66575-29-9 Coleonol

Colforsin (Forskolin, Coleonol) is a ubiquitous activator of eukaryotic adenylyl cyclase (AC) in a wide variety of cell types, commonly used to raise levels of cAMP in the study and research of cell physiology. Forskolin also activates PXR and FXR activity. Forskolin stimulates autophagy. *For Research & Development use only. Product is not intended for drug, household, or human consumption.

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7,496

ALADDIN SCIENTIFIC CORPORATION DICYANOCOBINAMIDE 5MG

NC3860205 DICYANOCOBINAMIDE 5MG

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7,497

E K INDUSTRIES EKI GRAM GENTIAN VIOLET STAIN

NC2186301 EKI GRAM GENTIAN VIOLET STAIN

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7,498

E K INDUSTRIES EKI GRAM SAFRANIN STAIN SOL

NC2186304 EKI GRAM SAFRANIN STAIN SOL

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7,499

Ambeed CAMPTOTHECIN-1G

NC3800621 CAMPTOTHECIN-1G

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7,500

Bio X Cell InVivoSIM Anti-Human PD-L1 (Avelumab biosimilar), 5 MG, 5 MG

InVivoSIM anti-human PD-L1 (Avelumab biosimilar) is a research-grade, non-therapeutic monoclonal antibody that targets human PD-L1 (CD274) and blocks PD-L1 interaction with PD-1 and CD80. Supplied for research use only. Store at 4C; do not freeze.

Non-therapeutic biosimilar monoclonal antibody matching therapeutic variable regions.
Targets human PD-L1 (CD274) and blocks PD-L1-PD-1 interactions.
Isotype: human IgG1, .
Formulation: PBS, pH 7.0, without stabilizers or preservatives.
Endotoxin: 0.5 EU/mg.
Purity: 95% by SDS-PAGE.
Aggregation: <5% by SEC.
Sterility ensured by 0.2 m filtration.
Available in multiple vial sizes including 5 mg.

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Bioactive Small Molecules

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Medchemexpress LLC HY-13030 10mg , (+)-JQ-1 CAS:1268524-70-4 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 4-[6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | 1206711-16-1 | 99.9% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-50904 50mg , Nintedanib CAS:656247-17-5 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-13030 10mg , (+)-JQ-1 CAS:1268524-70-4 Purity:>98%

Medchemexpress LLC 4-[6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | 1206711-16-1 | 99.9% | 1 ML

Medchemexpress LLC HY-50904 50mg , Nintedanib CAS:656247-17-5 Purity:>98%