Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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826
Tocris Bioscience™ Memantine hydrochloride
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CAS: 41100-52-1 Molecular Formula: C12H22ClN
| CAS | 41100-52-1 |
|---|---|
| Molecular Formula | C12H22ClN |
827
Tocris Bioscience™ BC-LI-0186
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Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor
| Target | Ras GTPase Inhibitors |
|---|---|
| CAS | 695207-56-8 |
| Purity | 98% |
| Chemical Name or Material | 4-[2,5-Dihydro-2,3-dimethyl-4-(1-methylethyl)-5-oxo-1 H-pyrazol-1-yl]-N-(2-phenoxyethyl)benzenesulfonamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H27N3O4S |
828
Tocris Bioscience™ TL4-12
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Potent MAP4K2 (GCK) inhibitor
| CAS | 1620820-12-3 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 4-Methyl-3-[[6-(methylamino)-4-pyrimidinyl]oxy]-N-[3-(4-methyl-1-piperazinyl)-5-(trifluoromethyl)phenyl]benzamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H27F3N6O2 |
829
Tocris Bioscience™ ci-IP3/PM
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Caged inositol triphosphate
830
Tocris Bioscience™ Pomalidomide 4'-alkylC4-acid
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Cereblon ligand with alkyl linker and terminal acid for onward chemistry
831
| CAS | 936563-96-1 |
|---|---|
| Molecular Formula | C25H24N6O2 |
832
Tocris Bioscience™ Formoterol hemifumarate
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 43229-80-7 Molecular Formula: C42H52N4O12
| CAS | 43229-80-7 |
|---|---|
| Molecular Formula | C42H52N4O12 |
833
Tocris Bioscience™ Risdiplam
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Selective SMN2 gene splicing modifier
| Target | DNA, RNA and Protein Synthesis Compounds |
|---|---|
| CAS | 1825352-65-5 |
| Purity | 0.98 |
| Chemical Name or Material | 7-(4,7-Diazaspiro[2.5 ]oct-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4 H-pyrido[1,2-a]pyrimidin-4-one |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H23N7O |
834
Tocris Bioscience™ 2-Hydroxypropyl-β-cyclodextrin
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 128446-35-5 Molecular Formula: C44H75O36
| CAS | 128446-35-5 |
|---|---|
| Molecular Formula | C44H75O36 |
835
Tocris Bioscience™ MK 2206 dihydrochloride
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Potent and selective allosteric Akt1, Akt2 and Akt3 inhibitor
| Target | Akt (Protein Kinase B) Inhibitors |
|---|---|
| CAS | 1032350-13-2 |
| Purity | 0.98 |
| Chemical Name or Material | 8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H21N5O.2HCl |
836
Tocris Bioscience™ 6877002
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CD40-TRAF6 interaction inhibitor
| Target | Additional Cytokine Receptor Products |
|---|---|
| CAS | 433249-94-6 |
| Purity | >99% |
| Chemical Name or Material | 3-[(2,5-Dimethylphenyl)amino]-1-phenyl-2-propen-1-one |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C17H17NO |
| Formula Weight | 251.32 |
837
Tocris Bioscience™ KYT 0353
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective inhibitor of L-type amino acid transporter 1 (LAT1)
838
Tocris Bioscience™ PROTAC™(H-PGDS)-8
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Negative control for PROTAC™(H-PGDS)-7 (Cat. No. 8004)
839
Tocris Bioscience™ Bosutinib
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 380843-75-4 Molecular Formula: C26H29Cl2N5O3
| CAS | 380843-75-4 |
|---|---|
| Molecular Formula | C26H29Cl2N5O3 |
840
Tocris Bioscience™ DLin-MC3-DMA
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Component of lipid nanoparticles (LNPs); ionizable cationic lipid