Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Tocris Bioscience™ GN 44028
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Potent HIF-1α inhibitor
Tocris Bioscience™ Reversan
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Selective MRP1 and P-gp inhibitor
| Inhibitors | Reversan |
|---|---|
| Product Type | Reversan |
| Molecular Weight (g/mol) | 441.52 |
| Purity | 0.95 |
| Recommended Storage | Store at -20°C |
Tocris Bioscience™ NVS PAK1 1
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Potent and selective PAK1 inhibitor
| CAS | 1783816-74-9 |
|---|---|
| Chemical Name or Material | (3S)-3-(2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-ylamino)-N-isopropylpyrrolidine-1-carboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C23H25ClF3N5O |
| Formula Weight | Observed MW: 479.93 |
| Assay Percent Range | >98% |
Tocris Bioscience™ Nefiracetam
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CAS: 77191-36-7 Molecular Formula: C14H18N2O2
| CAS | 77191-36-7 |
|---|---|
| Molecular Formula | C14H18N2O2 |
Tocris Bioscience™ Rosuvastatin calcium
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Potent HMG-CoA reductase inhibitor
| Target | HMG-CoA Reductase Inhibitors |
|---|---|
| CAS | 147098-20-2 |
| Purity | 99% |
| Chemical Name or Material | (3 R,5 S,6 E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl])-3,5-dihydroxyhept-6-enoic acid hemicalcium salt |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C22H27FN3O6S.1⁄2Ca |
| Formula Weight | Observed MW: 500.57 |
| Assay Percent Range | >99% |
Tocris Bioscience™ SNC 80
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CAS: 156727-74-1 Molecular Formula: C28H39N3O2
| CAS | 156727-74-1 |
|---|---|
| Molecular Formula | C28H39N3O2 |
Tocris Bioscience™ JNJ 55511118
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Selective, high affinity negative modulator of AMPA receptors containing TARP-γ8
| CAS | 2036081-86-2 |
|---|---|
| Chemical Name or Material | 5-[2-Chloro-6-(trifluoromethoxy)phenyl]-1,3-dihydro-2H-benzimidazol-2-one |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C14H8ClF3N2O2 |
| Formula Weight | Observed MW: 328.67 |
| Assay Percent Range | >98% |
Tocris Bioscience™ Epoprostenol
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CAS: 61849-14-7 Molecular Formula: C20H31NaO5
| CAS | 61849-14-7 |
|---|---|
| Molecular Formula | C20H31NaO5 |
Tocris Bioscience™ UK 370106
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CAS: 230961-21-4 Molecular Formula: C35H44N2O5
| CAS | 230961-21-4 |
|---|---|
| Molecular Formula | C35H44N2O5 |
Tocris Bioscience™ Clonidine hydrochloride
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CAS: 4205-91-8 Molecular Formula: C9H10Cl3N3
| CAS | 4205-91-8 |
|---|---|
| Molecular Formula | C9H10Cl3N3 |
Tocris Bioscience™ CDN 1163
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SERCA2 allosteric activator
| Target | Ca2+-ATPase Activators |
|---|---|
| CAS | 892711-75-0 |
| Purity | >98% |
| Chemical Name or Material | 4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide |
| Recommended Storage | Store at Room Temperature |
| Molecular Formula | C20H20N2O2 |
| Formula Weight | 320.38 |
Tocris Bioscience™ BQ 788 sodium salt
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Molecular Formula: C34H50N5NaO7
| Molecular Formula | C34H50N5NaO7 |
|---|
Tocris Bioscience™ VH 032 amide-alkylC7-amine
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VHL ligand with alkyl linker and terminal amine for onward chemistry
Tocris Bioscience™ VH 032 amide-PEG4-amine
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VHL ligand with PEG linker and terminal amine for onward chemistry
Tocris Bioscience™ Anle138b
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Oligomeric aggregation inhibitor
| Product Type | Inhibitor |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C16H11BrN2O2 |
| Formula Weight | 343.18 |