Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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991
Tocris Bioscience™ Staurosporine
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 62996-74-1 Molecular Formula: C28H26N4O3
| CAS | 62996-74-1 |
|---|---|
| Molecular Formula | C28H26N4O3 |
992
Tocris Bioscience™ Donepezil hydrochloride
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CAS: 120011-70-3 Molecular Formula: C24H30ClNO3
| CAS | 120011-70-3 |
|---|---|
| Molecular Formula | C24H30ClNO3 |
993
Tocris Bioscience™ AM 0902
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Potent and selective TRPA1 antagonist
| CAS | 1883711-97-4 |
|---|---|
| Chemical Name or Material | 1-[[3-[2-(4-Chlorophenyl)ethyl]-1,2,4-oxadiazol-5-yl]methyl]-1,7-dihydro-7-methyl-6H-purin-6-one |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C17H15ClN6O2 |
| Formula Weight | Observed MW: 370.79 |
| Assay Percent Range | >98% |
994
Tocris Bioscience™ Ro 6842262, >98%
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CAS: 1396006-71-5 Molecular Formula: C28H26N4O4
| CAS | 1396006-71-5 |
|---|---|
| Molecular Formula | C28H26N4O4 |
995
Tocris Bioscience™ WAY 208466 dihydrochloride
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CAS: 1207064-61-6 Molecular Formula: C17H20Cl2FN3O2S
| CAS | 1207064-61-6 |
|---|---|
| Molecular Formula | C17H20Cl2FN3O2S |
996
Tocris Bioscience™ RS 246204
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R-Spondin-1 substitute used to initiate small intestinal organoids
| Target | Compounds for Stem Cell Proliferation & Renewal |
|---|---|
| Recommended Storage | Store at -20°C |
997
Tocris Bioscience™ BIBN 4096
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Potent and selective CGRP antagonist
998
Tocris Bioscience™ SC 236
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CAS: 170569-86-5 Molecular Formula: C16H11ClF3N3O2S
| CAS | 170569-86-5 |
|---|---|
| Molecular Formula | C16H11ClF3N3O2S |
999
Tocris Bioscience™ LYN 1604 dihydrochloride
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Potent UNC-51-like kinase 1 (ULK1) agonist
| Target | ULK1 |
|---|---|
| CAS | 2310109-38-5 |
| Chemical Name or Material | 2-[Bis(2-methylpropyl)amino]-1-[4-[2-(2,4-dichlorophenyl)-2-(2-naphthalenylmethoxy)ethyl]-1-piperazinyl]ethanone dihydrochloride |
| Recommended Storage | Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date. |
| Molecular Formula | C33H43Cl2N3O2.2HCl |
1,000
Tocris Bioscience™ Pritelivir
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Potent and selective herpes simplex virus (HSV) helicase primase inhibitor
1,001
Tocris Bioscience™ Sonidegib
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Potent Smoothened receptor antagonist
| Target | Smoothened |
|---|---|
| CAS | 956697-53-3 |
| Molecular Formula | C26H26F3N3O3 |
1,002
Tocris Bioscience™ N-Acetylcysteine amide
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Glutathione (GSH) precursor; neuroprotective
| Target | Additional Antioxidant Compounds |
|---|---|
| CAS | 38520-57-9 |
| Chemical Name or Material | (2R)-2-(Acetylamino)-3-mercaptopropanamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C5H10N2O2S |
| Formula Weight | 162.21 |
1,003
Tocris Bioscience™ PD 168568 dihydrochloride
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CAS: 210688-56-5 Molecular Formula: C22H29Cl2N3O
| CAS | 210688-56-5 |
|---|---|
| Molecular Formula | C22H29Cl2N3O |
1,004
Tocris Bioscience™ EML 425
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Reversible and non-competitive CBP/p300 inhibitor
| Target | Histone Acetyltransferase Inhibitors |
|---|---|
| CAS | 1675821-32-5 |
| Purity | >98% |
| Chemical Name or Material | 5-[(4-Hydroxy-2,6-dimethylphenyl)methylene]-1,3-bis(phenylmethyl)-2,4,6(1H,3H,5H)-pyrimidinetrione |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C27H24N2O4 |
| Formula Weight | 440.49 |
1,005
Tocris Bioscience™ AZD 1208
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Potent pan Pim kinase inhibitor
| CAS | 1204144-28-4 |
|---|---|
| Chemical Name or Material | (5Z)-5-[[2-[(3R)-3-Amino-1-piperidinyl][1,1'-biphenyl]-3-yl]methylene]-2,4-thiazolidinedione |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H21N3O2S |
| Formula Weight | Observed MW: 379.48 |
| Assay Percent Range | >98% |