Crosslinking, Labeling and Protein Modification
CCOCCN1C(=O)C=CC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc(cc2)[N+]([O-])=O)cc1 | 250mg | 462125556](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502183523.JPG-250.jpg)
eMolecules 2249935-92-8 | Mal-PEG1-Val-Cit-PAB-PNP | Broadpharm739.739 | C34H41N7O12 | 98.000 | CC(C)[C@H](NC(=O)CCOCCN1C(=O)C=CC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc(cc2)[N+]([O-])=O)cc1 | 250mg | 462125556
Mal-PEG1-Val-Cit-PAB-PNP | Broadpharm | 2249935-92-8739.739 | C34H41N7O12 | 98.000 | CC(C)[C@H](NC(=O)CCOCCN1C(=O)C=CC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc(cc2)[N+]([O-])=O)cc1 | 250mg | 462125556
![eMolecules 2354291-37-3 | Gly-PEG3-endo-BCN | Broadpharm453.580 | C23H39N3O6 | 0.000 | NCC(=O)NCCCOCCOCCOCCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12 | 100mg | 550804569](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502183536.JPG-250.jpg)
eMolecules 2354291-37-3 | Gly-PEG3-endo-BCN | Broadpharm453.580 | C23H39N3O6 | 0.000 | NCC(=O)NCCCOCCOCCOCCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12 | 100mg | 550804569
Gly-PEG3-endo-BCN | Broadpharm | 2354291-37-3453.580 | C23H39N3O6 | 0.000 | NCC(=O)NCCCOCCOCCOCCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12 | 100mg | 550804569
Cayman Chemical DIhomoLInolenIc AcId 50mg
An elongation product of γ-linolenic acid (18:3), rapidly metabolized by fatty acid desaturases to produce arachidonic acid (20:4); metabolized through the cyclooxygenase pathway to produce 1-series prostaglandins; can reduce atopic dermatitis and atherosclerosis when added to the diet of mice
![eMolecules BDP 581/591 tetrazine | Broadpharm |575.430 | C32H28BF2N7O | 0.000 | Cc1nnc(nn1)-c1ccc(CNC(=O)CCC2=[N+]3C(C=C2)=Cc2ccc(\C=C\C=C\c4ccccc4)n2[B-]3(F)F)cc1 | 1mg | 761705821](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502460525.PNG-250.jpg)
eMolecules BDP 581/591 tetrazine | Broadpharm |575.430 | C32H28BF2N7O | 0.000 | Cc1nnc(nn1)-c1ccc(CNC(=O)CCC2=[N+]3C(C=C2)=Cc2ccc(\C=C\C=C\c4ccccc4)n2[B-]3(F)F)cc1 | 1mg | 761705821
BDP 581/591 tetrazine | Broadpharm |575.430 | C32H28BF2N7O | 0.000 | Cc1nnc(nn1)-c1ccc(CNC(=O)CCC2=[N+]3C(C=C2)=Cc2ccc(\C=C\C=C\c4ccccc4)n2[B-]3(F)F)cc1 | 1mg | 761705821
Cayman Chemical RItalInIc AcId 50mg
An inactive, major metabolite of methylphenidate; intended for forensic and biological research purposes
Aat Bioquest 5-FAM SE [5-Carboxyfluorescein succinimidyl ester] CAS 92557-80-7 (100 mg)
5-FAM SE is the amine-reactive succinimidyl ester of single isomer 5-FAM acid. This catalog is for 100 mg.
Biotium CD22(FR10B4), CF568 conjugate, 0.1mg/mL
Recognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD . It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF
Biotium CD38(AT1), CF568 conjugate, 0.1mg/mL
CD38 is a type II transmembrane glycoprotein that is present on early B- and T-cell lineages and activated B- and T-cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B-cells, mitogen-activated T-cells, monocytes and Ig-secreting plasma cells. CD38 is expressed on CD34 cells. The CD34 CD38- population of hematopoietic stems cells defines the most pluripotent cells (e.g. blast colony forming cells).Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium CDw78(DF1588), CF568 conjugate, 0.1mg/mL
This antibody reacts with a carbohydrate determinant, identified as CDw78 (Workshop V; Code CDw78.2). Epitope recognized by this MAb and Leu21 is the same. It is present on some immature and some peripheral blood B cells, and some B cell lines. Its expression is increased after B-cell activation in vitro. CDw78 is also found on tissue macrophages and on epithelial cells, but not on T cells, NK cells, monocytes, granulocytes and myeloid tissues. It appears that CDw78 is a determinant on a major histocompatibility complex (MHC) class II subpopulation.
Biotium CD38(AT1), CF568 conjugate, 0.1mg/mL
CD38 is a type II transmembrane glycoprotein that is present on early B- and T-cell lineages and activated B- and T-cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B-cells, mitogen-activated T-cells, monocytes and Ig-secreting plasma cells. CD38 is expressed on CD34 cells. The CD34 CD38- population of hematopoietic stems cells defines the most pluripotent cells (e.g. blast colony forming cells).Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium MALT-1(MT1/410), CF568 conjugate, 0.1mg/mL
Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not re
Biotium CMV-p65(CMV101), CF488A conjugate, 0.1mg/mL
Ten to forty percent of the patients with acquired immunodeficiency syndrome (AIDS) develop cytomegalovirus (CMV) infections. In some patients with AIDS, CMV is detected in the bronchoalveolar lavage fluid (BALF), urine, and other specimens, even when there are no symptoms of CMV disease. An indicator of active CMV infection is needed to facilitate the diagnosis of CMV disease in patients with AIDS or HIV infection. CMV p65 antigen was detected in the leukocytes of both the peripheral blood and BALF during the early phase of CMV disease.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium p53(PAb122), CF568 conjugate, 0.1mg/mL
Mutation and/or allelic loss of p53 is one of the causes of a variety of mesenchymal and epithelial tumors. If it occurs in the germ line, such tumors run in families. p53 Binds to a DNA consensus sequence, the p53 response element, and it regulates normal cell growth cycle events by activating transcription of genes, involved either in progression through the cycle, or causing arrest in G1 when the genome is damaged. In most transformed and tumor cells the concentration of p53 is increased 51000 fold over the minute concentrations (1000 molecules cell) in normal cells, principally due to the increased half-life (4 h) compared to that of the wild-type (20 min). p53 Localizes in the nucleus, but is detectable at the plasma membrane during mitosis and when certain mutations modulate cytoplasmic/nuclear distribution. p53 Is the most commonly mutated gene in spontaneously occurring human cancers. Mutations arise with an average frequency of 70% but incidence varies from zero in c