Crosslinking Reagents
eMolecules TargetMol DSG Crosslinker 100mg 726061665 T15171 0 000 79642-50-5 MFCD00153597 326 261 C13H14N2O8
TargetMol DSG Crosslinker 100mg 726061665 T15171 0 000 79642-50-5 MFCD00153597 326 261 C13H14N2O8
Uline Color Sensitive Photo Sensor F
Color Sensitive Photo Sensor For Uline Semi-Automatic Stretch Wrap Machines
Medchemexpress LLC Peg4-spdp | 1305053-43-3 | 488.57 g/mol | C20H28N2O8S2 | 250 MG
PEG4-SPDP is a cleavable polyethylene glycol (PEG4) spacer variant of the SPDP crosslinker used as an ADC linker and general bioconjugation reagent. It features an N-hydroxysuccinimide (NHS) ester for amine coupling and a 2-pyridyldithiol group for thiol coupling, providing a reducible disulfide linkage for controlled payload release in reducing environments.
- Cleavable disulfide linker for controlled payload release in reducing environments.
- Amine-reactive NHS ester for conjugation to lysine residues.
- 2-pyridyldithiol group for thiol coupling and disulfide bond formation.
- Suitable for antibody-drug conjugates and protein crosslinking.
- Stable as a solid at -20°C; store solutions at lower temperatures for short-term use.
Medchemexpress LLC 3,3'-dithiobispropionic acid bis-sulfosuccinimidyl ester disodium salt | 81069-02-5 | MFCD00054980 | 98.9% | 564.54 g/mol | C14H16N2O14S4 | 5 MG
DTSSP (3,3'-dithiobis(sulfosuccinimidyl propionate)) is a cleavable disulfide-containing crosslinker used in biochemical research as a reversible protein crosslinker and as a linker in antibody-drug conjugate (ADC) synthesis. It couples to primary amines via NHS-ester chemistry to form stable amide bonds and is designed to be cleaved under reducing conditions to release linked moieties.
- Cleavable disulfide-containing crosslinker enabling reversible linkage.
- Reacts with primary amines via NHS-ester chemistry to form stable amide bonds.
- Cleavable under reducing conditions for controlled release of conjugates.
- Suitable for antibody-drug conjugate linker synthesis and protein crosslinking.
- Available in small laboratory pack sizes for research use.
Medchemexpress LLC BS3 crosslinker (disodium) | 127634-19-9 | not stated | 98.0% | 572.43 g/mol | C16H18N2Na2O14S2 | 50 MG
BS3 Crosslinker disodium is a water-soluble, non-cleavable homobifunctional amine crosslinker used for bioconjugation and antibody-drug conjugate synthesis. It contains sulfosuccinimidyl reactive esters that selectively react with primary amines to form stable amide bonds, enabling protein crosslinking and labeling under aqueous conditions. The reagent is supplied as a solid of high purity and requires sealed storage away from moisture and light; in solution, long-term storage at -80°C is recommended.
Medchemexpress LLC trans-Sulfo-SMCC | 1286837-77-1 | 90.9% | 414.39 g/mol | C16H18N2O9S | 25 MG
trans-Sulfo-SMCC is a non-cleavable, membrane-permeable antibody-drug conjugate (ADC) crosslinker containing maleimide and N-hydroxysuccinimide (NHS) ester reactive groups for conjugation to sulfhydryl and amine groups. It is supplied as a solid for research use in bioconjugation and ADC linker development.
- Non-cleavable linker suitable for stable conjugation
- Membrane permeable to support intracellular delivery
- Maleimide and NHS-ester reactive groups for sulfhydryl and amine coupling
- Available in multiple pack sizes, including 25 mg
- Supplied with purity approximately 90.9%
- Molecular weight ~414.39 g/mol
Medchemexpress LLC Hexanoic acid, 6-azido-, 2,5-dioxo-1-pyrrolidinyl ester | 866363-70-4 | MFCD25968077 | 98.0% | 254.24 g/mol | C10H14N4O4 | 250 MG
N3-C5-NHS ester is a noncleavable antibody-drug conjugate (ADC) linker and click chemistry reagent that contains an azide group and an N-hydroxysuccinimide (NHS) ester for efficient amine coupling. It is used to introduce azide handles for copper-catalyzed azide-alkyne cycloaddition (CuAAC) and to activate carboxyl groups for conjugation to biomolecules.
- Noncleavable ADC linker suitable for bioconjugation
- Contains azide group for click chemistry (CuAAC)
- NHS ester functional group for coupling to primary amines
- Purity ≥98.0%
- Supplied as a colorless to light yellow liquid; soluble in DMSO
- Molecular weight 254.24 g/mol; formula C10H14N4O4
- Storage: pure form -20°C; in solvent short-term at -20°C to -80°C
Cayman Chemical 5 7DIchLRokynurenIc AcId 50mg
An NMDA receptor antagonist (Ki = 40 nM in a radioligand binding assay); selectively selectively inhibits glycine- over kainate-induced NMDA currents at 15 μM in Xenopus oocytes expressing rat NMDA receptors; reduces NMDA-induced neurotoxicity in primary rat cortical neurons from 1 to 10 μM; reverses mechanical hyperalgesia in magnesium-deficient rats in a dose-dependent manner from 0.97-97 nmol; blocks the positive ionotropic effect, hypertension, and increase in myocardial oxygen demand induced by electrical stimulation of the PVN in anesthetized rabbits; increases social interaction time and time spent in the open arms of the elevated plus maze; disinhibits conflict responding in the Cook and Davidson conditioned conflict paradigm
Cayman Chemical 1 3-DImethylurIc AcId 50mg
An active metabolite of caffeine and theophylline; scavenges hydroxyl radicals in a cell-free assay and inhibits t-butyl hydroperoxide-induced lipid peroxidation by 77% in isolated human erythrocyte membranes at 500 µM; induces contractions in isolated rabbit duodenal, jejunal, and ileal preparations; induces relaxation in isolated rabbit ascending colon preparations; intracerebral administration induces clonic convulsions in mice (ED50 = 360 nmol/animal); has been found in urinary caliculi
Medchemexpress LLC Dbco-sulfo-link-biotin | 1363444-70-5 | 653.77 g·mol⁻¹ | C31H35N5O7S2 | 1 MG
DBCO-Sulfo-Link-biotin is a water-soluble, cleavable click-chemistry linker that combines a dibenzocyclooctyne (DBCO) reactive group with a biotin affinity tag. It enables copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) for labeling azide-containing biomolecules and is used in biotinylation, protein labeling, and antibody-drug conjugate linker synthesis.
- Enables copper-free strain-promoted alkyne-azide cycloaddition (SPAAC).
- Provides a biotin tag for affinity capture and detection.
- Sulfo linker increases water solubility for aqueous bioconjugation.
- Suitable for biotinylation, protein labeling, and ADC linker incorporation.
Medchemexpress LLC Sulfo-Cy7-DBCO | 95.1% | 10 MG
Sulfo-Cy7-DBCO is a water-soluble derivative of cyanine 7 bearing a DBCO moiety for strain-promoted alkyne-azide cycloaddition (SPAAC). It provides near-infrared fluorescence with spectral properties comparable to Cy7 and is intended for bioconjugation and imaging applications.
- Water-soluble near-infrared fluorescent dye.
- DBCO functionality enables copper-free click conjugation (SPAAC).
- Spectral properties similar to Cy7 for NIR imaging compatibility.
- Provided at high purity (~95.1%).
- Supplied in small-mass quantities suitable for labeling workflows.
- Store sealed, away from moisture and light at 4°C; in solvent store at -80°C or -20°C as recommended.
Medchemexpress LLC DBCO-Sulfo-Link-biot 1mg
DBCO-Sulfo-Link-biotin TEA is a click chemistry intermediate containing a DBCO group which can undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group