Crosslinking Reagents
Vector Laboratories Sulfo S-HyNic Linker, 10 mg S-1002-010
Sulfo S-HyNic Linker (Water Soluble), 10 mg. S-HyNic heterobifunctional crosslinker is fundamental to SoluLINK bioconjugation technology. Sulfo-S-HyNic reacts with primary amines on proteins (through lysine amino acids) or amino-modified oligonucleotides or surfaces, introducing a HyNic linker that forms stable covalent conjugates with biomolecules possessing 4FB linkers. Sulfo-S-HyNic contains a Sulfo-NHS ester, which makes this linker water soluble. No DMF or other organic solvents are necessary to dissolve the linker prior to use.
Medchemexpress LLC Cyclooctyne-O-PFP ester | 886209-60-5 | 95.1% | 348.26 | C16H13F5O3 | 25 MG
Cyclooctyne-O-PFP ester is a cleavable ADC linker and click-chemistry reagent containing an alkyne functional group used to conjugate azide-containing molecules via azide-alkyne cycloaddition. It is supplied as a solid for research use and is commonly applied in bioconjugation and antibody-drug conjugate synthesis.
- Cleavable ADC linker for bioconjugation and antibody-drug conjugate synthesis.
- Reacts in copper-catalyzed and strain-promoted azide-alkyne cycloaddition.
- Supplied in small quantities suitable for research use and method development.
- High purity suitable for conjugation chemistry, with a molecular weight of 348.26 g·mol⁻¹.
Medchemexpress LLC Hexanoic acid, 6-azido-, 2,5-dioxo-1-pyrrolidinyl ester | 866363-70-4 | MFCD25968077 | 98.0% | 254.24 g/mol | C10H14N4O4 | 250 MG
N3-C5-NHS ester is a noncleavable antibody-drug conjugate (ADC) linker and click chemistry reagent that contains an azide group and an N-hydroxysuccinimide (NHS) ester for efficient amine coupling. It is used to introduce azide handles for copper-catalyzed azide-alkyne cycloaddition (CuAAC) and to activate carboxyl groups for conjugation to biomolecules.
- Noncleavable ADC linker suitable for bioconjugation
- Contains azide group for click chemistry (CuAAC)
- NHS ester functional group for coupling to primary amines
- Purity ≥98.0%
- Supplied as a colorless to light yellow liquid; soluble in DMSO
- Molecular weight 254.24 g/mol; formula C10H14N4O4
- Storage: pure form -20°C; in solvent short-term at -20°C to -80°C
Abcam Traut's reagent, RNA-protein crosslinking (sulfhydryl addition) agent, 500MG
MW 137.63 Da, Purity >90%. RNA-protein crosslinking (sulfhydryl addition) agent. Reacts with primary amines. Maintains charge properties similar to the original amino group.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC N3-C4-NHS ester | 478801-48-8 | 99.5% | 240.22 g/mol | C9H12N4O4 | 250 MG
N3-C4-NHS ester is a noncleavable antibody-drug conjugate (ADC) linker and click-chemistry reagent containing an azide group. It is used for bioconjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC), and is suitable for ADC synthesis and related chemical biology applications. Purity is 99.53%, molecular weight 240.22 g/mol, formula C9H12N4O4. Storage: pure form -20°C for long-term stability.
- Noncleavable ADC linker for antibody-drug conjugate synthesis.
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Compatible with strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO or BCN.
- High purity: 99.5% to support sensitive conjugation reactions.
- Stored at -20°C in pure form for up to 3 years.
Cayman Chemical Sulfo-SMCCsodIum salt 100mg
A water-soluble protein cross-linking reagent; has been used to conjugate anti-PD-L1 antibodies to the surface of platelets and Golgi-targeting peptides to platelet microparticle-mimetic nanoplatforms
Broadpharm Sulfo DBCO-UBQ-1, 1mg Purity: 95%, Formula: C47H46N9O9S
Sulfo DBCO-UBQ-1 serves as a click chemistry reagent uniting UBQ-1, which is a dark quencher with a polyaromatic-azo backbone that exhibits no native emission, with a sulfo group for improved hydrophilicity and DBCO for undergoing copper-free click chemistry.
BLD PHARMATECH CO LIMITED EDC·HCl, 25952-53-8, Purity: 99%, 100g
EDC·HCl, 25952-53-8, Purity: 99%, 100g