Protein Modification Reagents
Medchemexpress LLC Propargyl-PEG2-CH2COOH | 944561-46-0 | 95.0% | 202.20 | 100 MG
Propargyl-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Peg-based PROTAC linker
- Click chemistry reagent
- Contains an Alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
Vector Laboratories PHOTOPROBE (Long Arm) Biotin Kit for Nucleic Acid Labeling
PHOTOPROBE (Long Arm) Biotin is used to incorporate biotin at multiple sites along a nucleic acid without destroying or copying the original nucleic acid. It can be used to label DNA, RNA or PNA. The labeling reagent has a long linker arm to increase the accessibility of the biotin. Each kit contains PHOTOPROBE Biotin Reagent, Tris Buffer, sec-Butanol Precipitant, and Biotinylated DNA Standard, and can be used to label up to 250 µg of target or for up to 50 labeling reactions.
Medchemexpress LLC Tos-PEG4-THP | 86259-89-4 | 100 MG
Tos-PEG4-THP is a PEG-based PROTAC linker. It is utilized in the synthesis of PROTAC K-Ras Degrader-1. PROTACs are compounds containing two distinct ligands connected by a linker: one targets an E3 ubiquitin ligase, and the other targets a specific protein. These compounds leverage the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
- PEG-based PROTAC linker
- Composed of two ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- The other ligand targets a specific protein
- Utilizes the ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC HS-PEG3-CH2CH2NH2 hydrochloride | 2863676-86-0 | 95.0% | 100 MG
HS-PEG3-CH2CH2NH2 hydrochloride is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs function by leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs utilize two distinct ligands connected by a linker
- Selectively degrades target proteins through the ubiquitin-proteasome system
Broadpharm Azido-PEG12-acid | 1167275-20-3 | 1g
Azido-PEG12-acid | Putity: 98% | MW: 643.7 | 1167275-20-3 | 1g
Nanocs Biotin PEG Maleimide, 100mg
Purity: >95%, Solubility: Soluble in water, Biotin PEG Maleimide is one of Nanocs pegylated Biotinylation reagents with an activated maleimide group. Maleimide is able to react with thiol/sulfhydryl groups rapidly and specifically at neutral pH. Reaction between maleimide and thiol group enables fast conjugation of biotin tag to targeted molecules or material surfaces. Resulted biotin moiety can bind to avidin or streptavidin with high affinity. PEG linker between biotin and maleimide offers better water solubility, reduced steric hydrance and enhanced stability.
Medchemexpress LLC Cholesterol-PEG-azide | 85.7% | 3400 (average) | 5 MG
Cholesterol-PEG-azide (average MW 3400) is an amphiphilic cholesterol-polyethylene glycol conjugate bearing a terminal azide functional group. It serves as a clickable lipid anchor for bioconjugation and can self-assemble into micelles for use in drug delivery research and nanoparticle surface modification. Supplied as a white to off-white solid for research use.
- Provides an azide functional group for click chemistry.
- Amphiphilic structure enables micelle formation and membrane anchoring.
- Average PEG spacer (MW ~3400) offers flexible linker length.
- Suitable for drug delivery and nanoparticle surface modification studies.
- Stable when stored under recommended conditions (-20°C, protected from light).
STA PHARMACEUTICAL US LLC Azide-PEG3-L-alanine-Fmoc | 50 g | CAS 2054345-69-4 | InChIKey YTHKPQSMRZQREU-JOCHJYFZSA-N
Azide-PEG3-L-alanine-Fmoc is a Amino Acid reagent (Subcategory: Azido/Alkynyl AA) sold by WuXi TIDES. Offered in 50 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 2054345-69-4
- MDL: No data
- InChIKey: YTHKPQSMRZQREU-JOCHJYFZSA-N
- Molecular Weight: 484.509
- Molecular Formula: C24H28N4O7
- Purity: ≥95%
- Container Type: 250 mL HDPE
- Pack Size: 50 g
- Net Weight: 50 g
- Gross Weight: 89.8 g
- Commodity Code: 29299090
- Country Of Origin: China
- IUPAC: N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(2-(2-(2-azidoethoxy)ethoxy)ethyl)-D-serine
- SMILES: O=C(N[C@H](COCCOCCOCCN=[N+]=[N-])C(O)=O)OCC1C2=C(C=CC=C2)C3=C1C=CC=C3
Medchemexpress LLC Mc-peg2-va-pab-exatecan | 2845165-13-9 | 99.6% | 994.03 | C51H56FN7O13 | 10 MG
MC-PEG2-VA-PAB-Exatecan is an exatecan-based drug-linker conjugate designed for antibody-drug conjugate (ADC) research. It links the camptothecin-derived cytotoxic payload exatecan to a cleavable PEG2-Val-Cit-PAB linker to permit targeted intracellular release of the payload during ADC development.
- Exatecan payload confers potent topoisomerase I inhibition.
- Cleavable Val-Cit-PAB linker enables enzyme-triggered release inside target cells.
- PEG2 spacer improves solubility and conjugation flexibility.
- High reported purity supports reproducible research results.
- Available in mg-scale quantities suitable for ADC synthesis workflows.
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG6-CH2COOH | 5 g | CAS 437655-96-4 | MDL MFCD26142983
Fmoc-NH-PEG6-CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 5 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 437655-96-4
- MDL: MFCD26142983
- InChIKey: HANLHKUCDRJGKX-UHFFFAOYSA-N
- Molecular Weight: 561.628
- Molecular Formula: C29H39NO10
- Purity: ≥95%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azatetracosan-24-oic acid
- SMILES: O=C(NCCOCCOCCOCCOCCOCCOCC(O)=O)OCC1C2=C(C3=C1C=CC=C3)C=CC=C2
