Protein Modification Reagents
Medchemexpress LLC 4,7,10,13,16,19-hexaoxaeicosanoic acid | 1347750-72-4 | ≥95.0% | 324.37 g·mol⁻1 | C14H28O8 | 1 G
m-PEG5-CH2CH2COOH is a methoxy-terminated polyethylene glycol (PEG) linker with a terminal carboxylic acid used as a short, flexible spacer in PROTAC and bioconjugation chemistry.
- Methoxy-terminated PEG linker with terminal carboxylic acid.
- Suitable for PROTAC synthesis and bioconjugation.
- Purity: ≥95.0%.
- Molecular weight: 324.37 g·mol⁻1.
- CAS number: 1347750-72-4.
- Available in laboratory-scale package sizes, including 1 G.
Enzo Life Sciences Gefitinib-based PROTAC 3 (1mg). CAS: 2230821-27-7
Gefitinib-based PROTAC 3 is targeting on EGFR, consisting of Gefitinib as the warhead linked to VHL-recruiting ligand. Purity: ≥99%. Solubility: Soluble in DMSO (75 mg/mL). Insoluble in water. Long Term Storage: -20°C.
Medchemexpress LLC VH032-PEG5-C6-Cl (HaloPROTAC 2) | 1799506-06-1 | 99.9% | 783.41 | 50 MG
VH032-PEG5-C6-Cl, also known as HaloPROTAC 2, is a conjugate of E3 ligase ligands and a 21-atom-length linker. This compound incorporates the VH032 based VHL ligand and a 5-unit PEG linker.
- Conjugate of ligands for E3.
- Features a 21-atom-length linker with a halogen group connector.
- Incorporates a VH032 based VHL ligand.
- Includes a 5-unit PEG linker.
- Capable of inducing degradation of GFP-HaloTag7 in cell-based assays.
Broadpharm Amino-PEG16-acid | 196936-04-6 | MFCD11041162 | 100mg
Amino-PEG16-acid | Putity: 98% | MW: 794 | 196936-04-6 | MFCD11041162 | 100mg
Medchemexpress LLC m-PEG4-Tos 100mg | 62921-76-0 | 100 MG
m-PEG4-Tos is a tosylated polyethylene glycol (PEG4) reagent used as a PEG-based PROTAC linker and synthetic building block. It serves as a reactive tosylate for installing a PEG spacer in bifunctional degraders and related small-molecule conjugates. Supplied as a colorless to light yellow liquid at high purity, it is intended for research use and requires cold storage for long-term stability.
- Tosylated PEG4 spacer for efficient nucleophilic substitution.
- High purity (≥98.0% by NMR) suitable for synthesis.
- Colorless to light yellow liquid, simplifies handling and dispensing.
- Available in small synthetic quantities (e.g., 100 MG) for discovery work.
- Recommended cold storage to preserve stability in pure form or in solution.
Medchemexpress LLC Cl-C6-PEG4-C3-COOH | 2127391-58-4 | MFCD34469791 | 99.7% | 382.92 | C18H35ClO6 | 5 MG
Cl-C6-PEG4-C3-COOH is a bifunctional PROTAC linker that incorporates a chloroalkane handle for the synthesis of HaloPROTACs and other chloroalkane-containing bifunctional molecules. It is supplied as a high-purity liquid and is intended as a synthetic building block for chemical biology and drug discovery research.
- Bifunctional PROTAC linker for constructing chloroalkane-containing PROTACs.
- Molecular weight 382.92.
- CAS number 2127391-58-4.
- Purity 99.65%.
- Physical form: colorless to light yellow liquid; density 1.072 g/cm3.
- Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
- Storage: store at 4°C, protect from light; in solvent store -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC HY-128716A 100mg Medchemexpress, Pomalidomide-PEG3-C2-NH2 (TFA) CAS: Purity:>98%
Medchemexpress, HY-128716A 100mg Pomalidomide-PEG3-C2-NH2 (TFA) CAS: Pomalidomide-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical VH 032 amIde C7 AcId 25mg
A PROTAC precursor; has been used in the synthesis of PROTACs targeting ALK in cancer cells