Protein Modification Reagents
Medchemexpress LLC N3-Gly-Gly-Gly-Gly-Gly-OH | 2250433-77-1 | C10H15N7O6 | 5 MG
N3-Gly-Gly-Gly-Gly-Gly-OH is a click chemistry reagent that contains an azide group. It is capable of participating in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules possessing alkyne groups. Additionally, it can undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
- Contains an azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Undergoes ring strain-promoted alkyne-azide cycloaddition (SPAAC)
Medchemexpress LLC DBCO-PEG2-DBCO | 2639395-48-3 | C44H42N4O6 | 25 MG
DBCO-PEG2-DBCO is a click chemistry reagent that contains a DBCO group. It functions as a PEG linker with two terminal DBCO groups. These DBCO groups are frequently used for copper-free Click Chemistry reactions due to their strain-promoted high energy. The hydrophilic PEG chain in DBCO-PEG2-DBCO enhances its water solubility. This product is reagent grade and intended for research use only.
- Contains a DBCO group
- Functions as a PEG linker with two terminal DBCO groups
- Commonly utilized in copper-free click chemistry reactions
- Exhibits strain-promoted high energy
- Hydrophilic PEG chain enhances water solubility
- Reagent grade
- Intended for research use only
Medchemexpress LLC PROTAC STING Degrader-1 | 2762552-74-7 | C34H33N7O10 | 1 MG
PROTAC STING Degrader-1 is a PROTAC degrader targeting the STING pathway with a DC50 of 3.2 μM. It demonstrates high anti-inflammatory efficacy and can be utilized for studying conditions such as acute kidney injury and inflammatory bowel diseases (IBDs). The compound consists of a STING ligand, a CRBN ligand, and a linker.
- Degrades STING in a dose- and time-dependent manner
- Downregulates downstream signals of the STING pathway
- Shows no cytotoxicity in LO2, HEK293A, and C17.2 at doses below 10 μM
- Alleviates ischemic symptoms and reduces kidney weights in acute kidney injury models
- Ameliorates the severity of DSS-induced colitis
- Reduces the production of proinflammatory cytokines and transcription of ISGs
Cayman Chemical BIotIn-PEG4-NHS 50mg
An amine reactive reagent; has been used in the biotinylation of proteins and antibodies
![eMolecules Broadpharm / 140 PEG PE MW 550 / 5mg / 718091915 / BP-28307 / 95.000 / 474922-82-2 / [null] / 737.953 / C37H72NO11P](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502486701.JPG-250.jpg)
eMolecules Broadpharm / 140 PEG PE MW 550 / 5mg / 718091915 / BP-28307 / 95.000 / 474922-82-2 / [null] / 737.953 / C37H72NO11P
Broadpharm / 140 PEG PE MW 550 / 5mg / 718091915 / BP-28307 / 95.000 / 474922-82-2 / [null] / 737.953 / C37H72NO11P
Cayman Chemical ANTIBODY DBCO-amIn 500mg
A copper-free click chemistry reagent; has been used in the synthesis of clickable fluorescent probes
Selleck Chemical LLC Bestatin 10mg 58970-76-6 Ubenimex
Bestatin (Ubenimex) is a potent aminopeptidase-B and leukotriene (LT) A4 hydrolase inhibitor, used in the treatment of acute myelocytic leukemia. *For Research & Development use only. Product is not intended for drug, household, or human consumption.