Protein Modification Reagents

Medchemexpress LLC Pomalidomide-amido-PEG3-C2-NH2 | 2328070-52-4 | 99.6% | 476.48 g·mol-1 | C22H28N4O8 | 5 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

Pomalidomide-amido-PEG3-C2-NH2 is a pomalidomide-derived cereblon ligand-linker conjugate intended for PROTAC and chemical biology research. It couples a cereblon-binding motif to a three-unit PEG linker with a two-carbon spacer, offering a convenient chemical handle for attachment to target-binding ligands. The compound is supplied as an off-white to light yellow solid with high purity suitable for laboratory studies.

• High purity (99.6% by HPLC).
• Molecular weight 476.48 g·mol-1.
• Molecular formula C22H28N4O8.
• Physical form solid, off-white to light yellow.
• Provides a PEG3 linker and C2 spacer for conjugation.
• Designed for use as a cereblon ligand in PROTAC design.
• Available in small research quantities such as 5 mg.

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Medchemexpress LLC Mal-PEG4-VC-PAB-DMEA-PNU-159682 | 2259318-52-8 | 96.2% | 1559.62 | C74H98N10O27 | 1 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

Mal-PEG4-VC-PAB-DMEA-PNU-159682 is a drug-linker conjugate used in antibody-drug conjugate (ADC) research. It combines a cleavable maleimide-PEG4-valine-citrulline-PAB-DMEA linker with a potent cytotoxic payload to enable studies of conjugation chemistry, linker stability, and payload release in vitro.

• Cleavable valine-citrulline peptide linker enabling enzymatic release.
• Maleimide functional group for thiol conjugation to antibodies.
• PEG4 spacer to improve solubility and spacing between antibody and payload.
• Conjugated to a potent cytotoxin for payload delivery studies.
• Supplied in small pack sizes suitable for early stage research.

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

eMolecules​ N-bis(Azido-PEG10)-N-(PEG10-t-butyl ester) | Broadpharm |1604.926 | C71H141N7O32 | 95.000 | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 50mg | 599128873

N-bis(Azido-PEG10)-N-(PEG10-t-butyl ester) | Broadpharm |1604.926 | C71H141N7O32 | 95.000 | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 50mg | 599128873

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

eMolecules​ 882847-34-9 | Fmoc-NH-PEG6-CH2CH2COOH | Ambeed | MFCD06656474 | 575.655 | C30H41NO10 | 95.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 250mg | 525195262

Fmoc-NH-PEG6-CH2CH2COOH | Ambeed | 882847-34-9 | MFCD06656474 | 575.655 | C30H41NO10 | 95.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 250mg | 525195262

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Medchemexpress LLC Mal-amido-(CH2COOH)2 | 207613-14-7 | 99.2% | 284.22 g/mol | C11H12N2O7 | 5 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

Mal-amido-(CH2COOH)2 is a maleimidoethyl-containing intermediate used in the synthesis of hydrophilic antibody-drug conjugate (ADC) linkers. It is provided as a research-use building block for linker chemistry.

• Maleimidoethyl intermediate for ADC linker synthesis.
• High reported purity supports consistent chemical performance.
• Moderate molecular weight and polar functionality aid solubility in common organic solvents.
• Reactive maleimide moiety enables conjugation to thiol-containing biomolecules.
• Available in small research-scale quantities suitable for route development and linker optimization.

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Medchemexpress LLC 4,7,10,13-Tetraoxahexadecanediamide, N1,N16-bis[3-(11,12-didehydrodibenz[b,f]azocin-5(6H) | 2182601-68-7 | 97.4% | 100 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

DBCO-PEG4-DBCO is a versatile PEG-based PROTAC linker used in the synthesis of PROTACs. It also serves as a cleavable ADC linker for antibody-drug conjugate (ADC) synthesis. As a click chemistry reagent, it features a DBCO group that enables strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules.

• Functions as a PEG-based PROTAC linker
• Used in the synthesis of PROTACs
• Serves as a cleavable ADC linker
• Enables synthesis of antibody-drug conjugates (ADCs)
• Acts as a click chemistry reagent
• Contains a DBCO group for SPAAC reactions

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

eMolecules​ 2353409-81-9 | Gly-Gly-Gly-PEG3-TCO | Broadpharm515.608 | C23H41N5O8 | 98.000 | NCC(=O)NCC(=O)NCC(=O)NCCOCCOCCOCCNC(=O)OC1CCC\C=C\CC1 | 25mg | 563055167

Gly-Gly-Gly-PEG3-TCO | Broadpharm | 2353409-81-9515.608 | C23H41N5O8 | 98.000 | NCC(=O)NCC(=O)NCC(=O)NCCOCCOCCOCCNC(=O)OC1CCC\C=C\CC1 | 25mg | 563055167

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Medchemexpress LLC Cyanine5 alkyne (Alkyne-Cy5) | 1223357-57-0 | 98.2% | 556.18 | 50 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

Cyanine5 alkyne (Alkyne-Cy5) is a fluorescent dye utilized for labeling azide proteins, enabling analysis of post-translational modifications like glycosylation. It also functions as a mitochondrial OXPHOS inhibitor, hindering the growth of cancer stem cells (CSCs). This compound is a click chemistry reagent, featuring an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules.

• Enables analysis of post-translational modifications like glycosylation
• Functions as a mitochondrial OXPHOS inhibitor
• Hinders the growth of cancer stem cells (CSCs)
• Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
• Significantly inhibits 3D mammosphere formation in MCF7 cells

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

eMolecules​ DBCO-PEG4-PFP ester | Broadpharm |718.674 | C36H35F5N2O8 | 98.000 | Fc1c(F)c(F)c(OC(=O)CCOCCOCCOCCOCCNC(=O)CCC(=O)N2Cc3ccccc3C#Cc3ccccc23)c(F)c1F | 100mg | 411413975

DBCO-PEG4-PFP ester | Broadpharm |718.674 | C36H35F5N2O8 | 98.000 | Fc1c(F)c(F)c(OC(=O)CCOCCOCCOCCOCCNC(=O)CCC(=O)N2Cc3ccccc3C#Cc3ccccc23)c(F)c1F | 100mg | 411413975

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

eMolecules​ 2140807-42-5 | (S, R, S)-AHPC-PEG3-acid | Broadpharm662.800 | C32H46N4O9S | 0.000 | Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCC(O)=O)C(C)(C)C)cc1 | 500mg | 528284338

(S, R, S)-AHPC-PEG3-acid | Broadpharm | 2140807-42-5662.800 | C32H46N4O9S | 0.000 | Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCC(O)=O)C(C)(C)C)cc1 | 500mg | 528284338

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

eMolecules​ 2353410-19-0 | Bromoacetamido-PEG5-DOTA | Broadpharm787.703 | C30H55BrN6O13 | 0.000 | OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCCOCCOCCNC(=O)CBr)CCN(CC(O)=O)CC1 | 10mg | 550804510

Bromoacetamido-PEG5-DOTA | Broadpharm | 2353410-19-0787.703 | C30H55BrN6O13 | 0.000 | OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCCOCCOCCNC(=O)CBr)CCN(CC(O)=O)CC1 | 10mg | 550804510

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Chemscene ChemScene | Amino-PEG1-C2-acid | 5G | CS-0114519 | 0.98 | 144942-89-2| MFCD22017475 | 133.15

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

ChemScene | Amino-PEG1-C2-acid | 5G | CS-0114519 | 0.98 | 144942-89-2| MFCD22017475 | 133.15

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

eMolecules​ 2629308-66-1 | Fmoc-NH-PEG11-CH2COOH | Broadpharm | MFCD30723257 | 781.893 | C39H59NO15 | 95.000 | OC(=O)COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 1g | 340377163

Fmoc-NH-PEG11-CH2COOH | Broadpharm | 2629308-66-1 | MFCD30723257 | 781.893 | C39H59NO15 | 95.000 | OC(=O)COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 1g | 340377163

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

eMolecules​ DSPE-PEG13-NHS | Broadpharm |1517.915 | C75H141N2O26P | 95.000 | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OCCNC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)OC(=O)CCCCCCCCCCCCCCCCC | 25mg | 761705553

DSPE-PEG13-NHS | Broadpharm |1517.915 | C75H141N2O26P | 95.000 | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OCCNC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)OC(=O)CCCCCCCCCCCCCCCCC | 25mg | 761705553

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Chemscene ChemScene | Mal-PEG2-NHS ester | 250MG | CS-0105019 | 0.98 | 1433997-01-3| MFCD24539465 | 354.31

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

ChemScene | Mal-PEG2-NHS ester | 250MG | CS-0105019 | 0.98 | 1433997-01-3| MFCD24539465 | 354.31

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More