Protein Modification Reagents
Medchemexpress LLC Azide-PEG4-VC-PAB-doxorubicin | 99.6% | 1222.25 | C57H75N9O21 | 25 MG
Azide-PEG4-VC-PAB-doxorubicin is an azide-functionalized PEG4 val-cit-PAB linker conjugated to doxorubicin used to prepare antibody-drug conjugates and for click-chemistry applications.
- Contains an azide group for copper-catalyzed and strain-promoted azide-alkyne cycloaddition reactions.
- Includes a protease-cleavable Val-Cit-PAB linker for intracellular payload release.
- Contains doxorubicin as the cytotoxic payload (anthracycline class).
- High listed purity suitable for research (soluble in DMSO at 100 mg/mL).
- Store as a solid at recommended low temperatures for long-term stability.
Medchemexpress LLC Cholesterol-SA-PEG-azide | 90.0% | 10 MG
Cholesterol-SA-PEG-Azide (MW 2000) is a cholesterol-conjugated polyethylene glycol derivative linked via succinic acid and terminated with an azide. Supplied as a powder with reported purity around 90%, it is used in liposome and nanoparticle formulation and provides a bioorthogonal azide handle for click conjugation.
- Provides cholesterol anchoring for liposomal or nanoparticle membranes.
- Contains a terminal azide for copper-catalyzed azide-alkyne click chemistry.
- Average PEG molecular weight ~2,000 to modulate circulation and steric properties.
- Supplied as a powder; store cold to preserve stability.
- Reported purity ~90%, suitable for formulation and conjugation research.
Medchemexpress LLC CY7-N3 (Sulfo-Cyanine7-N3) | 97.6% | 763.95 | 5 MG
CY7-N3 (Sulfo-Cyanine7-N3) is a water-soluble Near-Infrared (NIR) dye azide designed for Click Chemistry. It possesses an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
- Water-soluble NIR dye azide
- Contains an azide group for Click Chemistry
- Can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Can undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC)
eMolecules Methyltetrazine-PEG23-NH-Boc | Broadpharm |1344.595 | C62H113N5O26 | 0.000 | Cc1nnc(nn1)-c1ccc(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OC(C)(C)C)cc1 | 5mg | 411413934
Methyltetrazine-PEG23-NH-Boc | Broadpharm |1344.595 | C62H113N5O26 | 0.000 | Cc1nnc(nn1)-c1ccc(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OC(C)(C)C)cc1 | 5mg | 411413934
Biotium Insulin(E2-E3), CF594 conjugate, 0.1mg/mL
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have
![eMolecules 14-(Azide-PEG3-ethylcarbamoyl)tridecanoic-t-butyl ester | Broadpharm |514.708 | C26H50N4O6 | 0.000 | CC(C)(C)OC(=O)CCCCCCCCCCCCC(=O)NCCOCCOCCOCCN=[N+]=[N-] | 100mg | 784455381](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502473284.JPG-250.jpg)
eMolecules 14-(Azide-PEG3-ethylcarbamoyl)tridecanoic-t-butyl ester | Broadpharm |514.708 | C26H50N4O6 | 0.000 | CC(C)(C)OC(=O)CCCCCCCCCCCCC(=O)NCCOCCOCCOCCN=[N+]=[N-] | 100mg | 784455381
14-(Azide-PEG3-ethylcarbamoyl)tridecanoic-t-butyl ester | Broadpharm |514.708 | C26H50N4O6 | 0.000 | CC(C)(C)OC(=O)CCCCCCCCCCCCC(=O)NCCOCCOCCOCCN=[N+]=[N-] | 100mg | 784455381
Medchemexpress LLC FAK ligand-Linker Conjugate 1 | 2307461-45-4 | 98.9% | 583.58 | 5 MG
FAK ligand-Linker Conjugate 1 incorporates a ligand for FAK and a PROTAC linker, which recruits E3 ligases (such as VHL, CRBN, MDM2, and IAP). It can be extensively used for PROTAC-mediated protein degradation.
- Purity: 98.91%
- Appearance: Solid
- Color: White to off-white
- Solubility: In Vitro: DMSO : 100 mg/mL (171.36 mM; Needs ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of the product, so newly opened DMSO should be used).
- Storage: Powder: -20°C for 3 years, 4°C for 2 years. In solvent: -80°C for 2 years, -20°C for 1 year.
eMolecules 125220-94-2 | m-PEG24-acid | Broadpharm | MFCD13184958 | 1117.324 | C50H100O26 | 96.000 | COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O | 1g | 353441926
m-PEG24-acid | Broadpharm | 125220-94-2 | MFCD13184958 | 1117.324 | C50H100O26 | 96.000 | COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O | 1g | 353441926
Medchemexpress LLC endo-BCN-PEG2-alcohol | 1807501-85-4 | 98.0% | 325.40 | 25 MG
endo-BCN-PEG2-alcohol is a PEG-based PROTAC linker employed in the synthesis of PROTACs. This compound functions as a click chemistry reagent, featuring a BCN group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
- PEG-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Functions as a click chemistry reagent.
- Contains a BCN group for strain-promoted alkyne-azide cycloaddition (SPAAC).
Medchemexpress LLC Propargyl-PEG6-N3 | 1198080-03-3 | 250 MG
Propargyl-PEG6-N3 is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This compound functions as a click chemistry reagent, containing an Azide group. It can participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules that possess Alkyne groups, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs are designed with two distinct ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other a target protein, enabling the selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
- Peg-based protac linker
- Used in protac synthesis
- Click chemistry reagent
- Contains an azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC)
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG5-CH2COOH | 100 g | CAS 635287-26-2 | InChIKey LNIFRTLAPAPKAG-UHFFFAOYSA-N
Fmoc-NH-PEG5-CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 100 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 635287-26-2
- MDL: No data
- InChIKey: LNIFRTLAPAPKAG-UHFFFAOYSA-N
- Molecular Weight: 517.575
- Molecular Formula: C27H35NO9
- Purity: ≥95%
- Container Type: 500 mL HDPE
- Pack Size: 100 g
- Net Weight: 100 g
- Gross Weight: 160.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19-hexaoxa-4-azahenicosan-21-oic acid
- SMILES: O=C(COCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
Medchemexpress LLC Propargyl-PEG4-O-C1-NHS ester | 1161883-51-7 | 100 MG
Propargyl-PEG4-O-C1-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an alkyne group capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAC) with molecules containing azide groups.
- Target PROTAC linkers
- Part of the PROTAC pathway
- Functions as a click chemistry reagent
- Contains an alkyne group for copper-catalyzed azide-alkyne cycloaddition
- Used in the synthesis of PROTACs
- Utilizes the intracellular ubiquitin-proteasome system to selectively degrade target proteins
eMolecules 2698339-21-6 | N-(PEG1-acid)-L-Lysine-amido-Mal TFA salt | Broadpharm412.443 | C18H28N4O7 | 98.000 | NC(CCCCNC(=O)CCOCCC(O)=O)C(=O)NCCN1C(=O)C=CC1=O | 100mg | 649280889
N-(PEG1-acid)-L-Lysine-amido-Mal TFA salt | Broadpharm | 2698339-21-6412.443 | C18H28N4O7 | 98.000 | NC(CCCCNC(=O)CCOCCC(O)=O)C(=O)NCCN1C(=O)C=CC1=O | 100mg | 649280889