Protein Modification Reagents
CCOCCOCCN1C(=O)C=CC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1 | 50mg | 368397818](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502203338.JPG-250.jpg)
eMolecules 2055041-38-6 | Mal-PEG2-Val-Cit-PAB-OH | Broadpharm | MFCD29918233 | 618.688 | C29H42N6O9 | 0.000 | CC(C)[C@H](NC(=O)CCOCCOCCN1C(=O)C=CC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1 | 50mg | 368397818
Mal-PEG2-Val-Cit-PAB-OH | Broadpharm | 2055041-38-6 | MFCD29918233 | 618.688 | C29H42N6O9 | 0.000 | CC(C)[C@H](NC(=O)CCOCCOCCN1C(=O)C=CC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1 | 50mg | 368397818
eMolecules Cbz-N-amido-PEG15-amine | BroadpharmMFCD30723279 | 855.029 | C40H74N2O17 | 97.000 | NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCc1ccccc1 | 1g | 340376868
Cbz-N-amido-PEG15-amine | BroadpharmMFCD30723279 | 855.029 | C40H74N2O17 | 97.000 | NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCc1ccccc1 | 1g | 340376868
Medchemexpress LLC M-PEG15-NHS ester | 00-00-0 | 98.0% | C39H73NO20 | 10MG
m-PEG15-NHS ester is a methoxy-terminated polyethylene glycol (PEG) N-hydroxysuccinimide ester used as a hydrophilic linker in PROTAC synthesis and bioconjugation. It supplies an amine-reactive NHS group for covalent coupling to primary amines and a PEG15 spacer to improve solubility, flexibility, and distance between conjugated moieties.
- Provides an NHS ester for efficient amine coupling.
- Contains a methoxy-terminated PEG15 spacer to increase solubility.
- High purity (98.0%) suitable for research applications.
- Storage recommended at -20°C, sealed and protected from moisture and light.
- Available in multiple package sizes to support different scales of synthesis.
Medchemexpress LLC Mpro inhibitor N3 hemihydrate | MFCD00274570 | 99.9% | 698.81 | C35H50N6O9 | 5 MG
Mpro inhibitor N3 hemihydrate is a small-molecule inhibitor of coronavirus main protease (Mpro) provided as a white to off-white solid hemihydrate for biochemical and antiviral research; product page lists purity, storage, and solubility information for experimental planning.
- Potent inhibitor of coronavirus main protease with reported cellular activity.
- High purity (99.86%).
- Supplied as a white to off-white solid hemihydrate.
- Stable when stored as powder at -20°C for up to 3 years.
- High solubility in DMSO (100 mg/mL) suitable for in vitro assays.
- Formulated for small-scale research applications.
Medchemexpress LLC Endo-BCN-PEG2-alcohol | 1807501-85-4 | 98.0% | C17H27NO5 | 10MG
endo-BCN-PEG2-alcohol is a PEG-based linker that combines a strained bicyclo[6.1.0]non-4-yne (BCN) reactive group with a terminal hydroxyl. It is intended for use in copper-free click chemistry, bioconjugation, and linker assembly in PROTAC synthesis.
- Contains BCN strained alkyne for copper-free click reactions.
- Terminal alcohol enables further functionalization.
- PEG2 spacer increases hydrophilicity and reduces steric hindrance.
- Suitable for PROTAC linker assembly and bioconjugation applications.
- Comes with analytical documentation and storage recommendations.
Medchemexpress LLC Nh2-peg4-dota | 2090232-34-9 | 97.0% | 622.71 | C26H50N6O11 | 25mg
NH2-PEG4-DOTA is a bifunctional DOTA-type metal chelator NH2-PEG4-DOTA can be conjugated with Dextran for quantitative analysis in the presence of a highly luminescent complex NH2-PEG4-DOTA can also bind to radionuclides to prepare radionuclide drug conjugates (RDCs) RDCs have the ability to specifically target biomolecules and can be used in medical imaging or therapy
Medchemexpress LLC 5,8,11,14-tetraoxa-2-azahexadecanedioic acid, 1-(9H-fluoren-9-yl)methyl ester | 437655-95-3 | MFCD26142981 | 99.5% | 473.52 g·mol⁻¹ | C25H31NO8 | 1 G
Fmoc-NH-PEG4-CH2COOH is an Fmoc-protected PEG4 linker bearing a terminal carboxylic acid. It is used as a building block in peptide synthesis, and in the design of antibody-drug conjugate (ADC) and PROTAC linkers, providing a short hydrophilic spacer and an Fmoc-protected amine for orthogonal coupling chemistry.
- Provides an Fmoc-protected amine for orthogonal deprotection and coupling.
- Contains a PEG4 spacer to increase solubility and flexibility.
- Terminal carboxylic acid enables standard amide bond formation.
- Solid powder form suitable for storage and handling in synthesis workflows.
- Commonly used in medicinal chemistry for linker and conjugation strategies.
Medchemexpress LLC DSPE-PEG-SH | 90.0% | 1,000 Da | C44H86NO10PS | 100 MG
DSPE-PEG-SH (MW 1000) is a thiol-terminated pegylated phospholipid composed of a DSPE lipid anchor linked to an approximately 1,000 Da polyethylene glycol chain ending in a free sulfhydryl. The amphiphilic molecule integrates into lipid bilayers and is used to functionalize liposomes and nanoparticles and to enable covalent conjugation to maleimide-activated ligands.
- Provides a thiol functional group for covalent conjugation.
- Anchors into lipid bilayers via the DSPE lipid tail.
- Enhances colloidal stability and circulation through PEGylation.
- Suitable for surface functionalization of liposomes and nanoparticles.
- Average molecular weight approximately 1,000 Da.
- Typical purity around 90%.
![Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[poly(ethylene glycol)-maleimide] ammonium | 474922-22-0 | >95.0% | 3,400 Da | (C2H4O)nC51H92N3O13P.H3N | 250 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000281718.png-250.jpg)
Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[poly(ethylene glycol)-maleimide] ammonium | 474922-22-0 | >95.0% | 3,400 Da | (C2H4O)nC51H92N3O13P.H3N | 250 MG
DSPE-PEG-Maleimide (MW 3400) ammonium is a PEGylated phospholipid bearing a terminal maleimide group and supplied as the ammonium salt. It is used to introduce thiol-reactive functionality into liposomes, micelles, and other nanostructured lipid carriers for conjugation of peptides, proteins, and thiolated ligands in drug delivery and nanomedicine research.
- Provides a terminal maleimide for selective conjugation to thiol groups.
- PEG spacer (MW ~3,400) improves steric stabilization and circulation time.
- DSPE lipid anchor enables stable incorporation into lipid bilayers and micelles.
- Ammonium salt form aids solubility and handling in formulation workflows.
- Typical purity ≥95% suitable for research applications; verify COA for critical uses.
Medchemexpress LLC 3,6,9,12-Tetraoxatetradecane-1,14-diamine | 68960-97-4 | 98.0% | 236.31 | 250 MG
Amino-PEG4-C2-amine is a PEG-based (4 units) PROTAC linker that can be used in the synthesis of PROTACs.
- Peg-based (4 units) protac linker
- Used in the synthesis of protacs
eMolecules 2170240-96-5 | Medchem Express | Azido-PEG4-hydrazide | 50mg | 600899956 | HY-140814 | 305.335 | C11H23N5O5
Ambeed | 3-Bromo-4-(4455-tetramethyl-132-dioxaborolan-2-yl)pyridine | 250mg | 521437554 | A341459 | 458532-92-8 | MFCD06798250 | 283.960 | C11H15BBrNO2
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