Cytokines and Receptors Reagents and Kits
Creative Biomart Interleukin-8 (IL-8) Protein
Interleukin 8 (IL-8 or CXCL8) is a member of the CXC cytokine family and is produced by macrophages, epithelial, smooth muscle, and endothelial cells. IL-8 binds the G protein-coupled serpentine receptors CXCR1 and CXCR2. IL-8 recruits innate immune cells, induces phagocytosis, and stimulate angiogenesis. Recombinant human Interleukin 8 is a non-glycosylated protein monomer, containing 77 amino acids and having a molecular mass of 8.9 kDa.
Creative Biomart Interleukin 7 (IL-7) Protein
Interleukin 7 (IL-7) protein is produced by E. coli expression system.
American Research Products Inc Rat Interleukin 12 IL 12 P70
Rat Interleukin 12 IL-12/P70 ELISA KIT from CUSABIO Detection Range 3 12 pg/mL-200 pg/mL Sensitivity 0 78 pg/mL Sample serum plasma tissue homogenates Method Sandwich
Raybiotech Inc G-Series Porcine Cytokine Array 5 Kit.
Detects 10 Porcine Cytokines. Suitable for all liquid sample types. Semi-Quantitative, Sandwich-based, Glass Slide Antibody Array Screen and compare protein expression levels with high specificity and sensitivity (pg/ml levels). The glass slide array allows for high throughput and low sample consumption; as little as 10 µl of original sample required per array. Proteins detected: Eotaxin-1, Erythropoietin, FGF-21, Galectin-9, IFN beta, IGF-2, IL-21, IL-28B, PlGF-2, SCF
Meso Scale Discovery U-PLEX Proinflam Combo 1, multiplex immunoassay, 5 plate size, 2 plates provided, 96-well, detection limits sub- to low pg/mL, sample types: serum, plasma, cell culture supernatant
The U-PLEX Proinflam Combo 1 (NHP) is a multiplex immunoassay designed for measuring nine key proinflammatory biomarkers in non-human primate samples. Utilizing advanced U-PLEX technology with electrochemiluminescence detection, this kit allows for precise cytokine and chemokine analysis across various sample types. It offers low detection limits and a broad dynamic range, making it an efficient solution for researchers. The kit includes two plates, enabling separation of incompatible assays, ensuring accurate performance for each biomarker.
- Assay type: Multiplex immunoassay
- Detection limits: sub- to low pg/mL range
- Number of plates: 2
- Plate type: 96-well
- Compatible sample types: Serum, plasma, cell culture supernatant
- Research use only: true
- Storage condition: Multi-component
Biolegend Brilliant Violet 421TM anti-hu
Brilliant Violet 421™ anti-human CX3CR1 [2A9-1]; Isotype: Rat IgG2b, κ; Reactivity: Human; Apps: FC; Size: 25 tests
![Biolegend PE/Cyanine7 anti-human CD25 [S20019D]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 25 tests](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502530524.png-250.jpg)
Biolegend PE/Cyanine7 anti-human CD25 [S20019D]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 25 tests
PE/Cyanine7 anti-human CD25 [S20019D]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 25 tests
![Biolegend Brilliant Violet 421™ anti-human CD25 [S20019D]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 100 tests](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502530519.png-250.jpg)
Biolegend Brilliant Violet 421™ anti-human CD25 [S20019D]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 100 tests
Brilliant Violet 421™ anti-human CD25 [S20019D]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 100 tests
Genscript Corporation SCF, Human (P. pastoris-expressed)
Stem cell factor (also known as SCF, KIT-ligand, KL, or steel factor) is a cytokine that binds to the c-KIT receptor (CD117). SCF can exist both as a transmembrane protein and a soluble protein. It stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures and has been shown to act synergistically with colony stimulating factors. SCF plays an important role in the hematopoiesis during embryonic development. SCF can regulates HSCs in the stem cell niche in the bone marrow. SCF has been shown to increase the survival of HSCs in vitro and contributes to the self-renewal and maintenance of HSCs in-vivo.
Genscript Corporation IL-20, Human
IL-20 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 is a hematopoietic growth factor capable of stimulating colony formation by CD34+ multipotential progenitors, but not by other progenitor cells. IL-20 signals through a receptor system composed of type I IL-20R-α and type II IL-20R-β. Over-expression of IL-20 in keratinocytes expressing both receptor subunits has been implicated in the induction of inflammatory skin disease.
Genscript Corporation IL-17F, Human
Human IL-17F is synthesized as a 153 aa precursor with a 20 aa signal sequence and a 133 aa mature region. Like IL-17A, IL-17F contains one potential site for N-linked glycosylation. IL-17A and IL-17F share 50% aa sequence identity. IL17-F homodimer is produced by an activated subset of CD4+ T cells, termed Th17. IL17-F has been shown to stimulate proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis.
Genscript Corporation IL-13 Variant, Human
The human IL-13 cDNA encodes a 132 amino acid protein containing a proposed 20 amino acid signal peptide. Human IL-13 shares approximately 30% amino acid sequence homology to human IL-4 and the two cytokines exhibit overlapping biological activities. Human IL-13 is produced by activated Th0, Th1-like Th2-like and CD8 T cells. Similarly to IL-4, IL-13 has multiple effects on the differentiation and functions of monocytes/macrophages. IL-13 can suppress the cytotoxic functions of monocytes/macrophages. It can also suppress the production of proinflammatory cytokines and upregulate the production of IL-1ra by monocytes/macrophages.
Genscript Corporation IL-17F, Human
Human IL-17F is synthesized as a 153 aa precursor with a 20 aa signal sequence and a 133 aa mature region. Like IL-17A, IL-17F contains one potential site for N-linked glycosylation. IL-17A and IL-17F share 50% aa sequence identity. IL17-F homodimer is produced by an activated subset of CD4+ T cells, termed Th17. IL17-F has been shown to stimulate proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis.