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Fully sequenced samples of complimentary DNA synthesized from single-stranded, non-mammalian RNA. A wide variety of gene inserts are available. Ideal for use in gene cloning, as gene probes, and cDNA library in creation.
Recognizes the D1 domain of an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds identified as CD50 or ICAM-3 (Leucocyte Workshop VI) CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C This MAb is excellent for staining of formalin/paraffin tissues Primary antibodies are available purified or with a selection of fluorescent CF Dyes and other labels CF Dyes offer exceptional brightness and photostability Note Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors
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ExoBrite 410/450 CD29 Flow Antibody is optimized for detection of CD29/Integrin beta-1 on isolated exosomes by flow cytometry The conjugate has Ex/Em at 408/452 nm for detection in the Pacific Blue channel Recommended for instruments optimized for small particle flow 25 tests
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Umibecestat (CNP520) is a potent and selective beta-secretase (BACE-1) inhibitor used in Alzheimer's disease research. It is supplied as a research-grade compound for in vitro biochemical and cellular studies.
Potent BACE-1 inhibition (IC50 ~11 nM human BACE-1).
High purity suitable for biochemical assays (>99.8%).
Available as solid quantities (e.g., 10 mg) and as 10 mM solution in DMSO.
Molecular formula C19H15ClF7N5O2 and molecular weight 513.80 g/mol.
Commonly used in BACE-1 pathway and Alzheimer's disease research.
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An aspirin-triggered epimer of resolvin D3; has been found in mouse inflammatory exudates; reduces transmigration of neutrophils into the peritoneal cavity, as well as decreases the levels of IL-6 and increases the levels of IL-10 in inflammatory exudate in a mouse model of zymosan-induced peritonitis at 10 ng/animal; activates GPR32 in a β-arrestin reporter assay and increases phagocytosis to a greater degree in CHO cells overexpressing GPR32 compared to mock-transfected cells; increases phagocytosis of etoposide-generated tumor cell debris by monocyte-derived macrophages in H460 human lung carcinoma cells in a concentration-dependent manner; inhibits tumor growth in a mouse model of Lewis lung carcinoma at 0.6 UG/kg per day
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More