Non-Mammalian cDNA
Eurofins Discoverx PathHunter Rat HTR2C (5-HT2C) β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Rat HTR2C (5-HT2C) β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure rHTR2C (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Invivogen E. coli ssDNA / LyoVec™ 200ug, E. coli single-stranded DNA/LyoVec complex
E. coli ssDNA/LyoVec™ is a Toll-like receptor 9 (TLR9) ligand. It comprises E. coli ssDNA an ultrapure, endotoxin-free preparation of bacterial single‑stranded DNA (ssDNA) which is complexed with the cationic lipid-based transfection reagent LyoVec™. This allows for a better internalization of the immunostimulatory DNA to the acidic endosomal compartment where TLR9 is expressed.TLR9 specifically recognizes CpG DNA that is unmethylated and single-stranded (ss). Upon recognition, it initiates a signaling cascade leading to the activation of the transcription factors NF-κB, AP-1, and interferon regulatory factor 7 (IRF7) with the subsequent production of pro‑inflammatory cytokines. Methylation of the cytosine within the CpG motif strongly reduces the affinity of TLR9 [1, 2]. In addition, double‑stranded (ds) CpG DNA is a much weaker stimulator of TLR9 compared to its ss counterpart [1]. Unlike mammalian DNA, bacterial DNA is rich in unme
Invivogen HEK-Blue™ hTLR7 Cells, NF-κB–SEAP Reporter Line, TLR7-Dependent Signaling, 3-7 x 10^6 cells
HEK-Blue™ hTLR7 cells are engineered HEK293 cells designed for TLR7 receptor signaling studies. They contain a robust NF-κB–SEAP reporter system, enabling precise monitoring of NF-κB activation upon TLR7 stimulation. Ideal for researchers, they facilitate the investigation of TLR7 agonists and inhibitors, offering distinct advantages over standard cell lines due to their unique modifications, including a stable response to specific ligands.
ABclonal Technology AFTSpin Universal Plant Fast DNA Extraction Kit
This kit is suitable for rapid and simple extraction of genomic DNA from various fresh plant tissues or cultured plant cells. The extracted genomic DNA fragments are large with high purity and stability and can be directly used for PCR, digestion, hybridization and others. The extraction process does not require phenol/chloroform extraction.
Cayman Chemical RET EXrAClular DomaInhum 10ug
Source: Active recombinant human N-terminal GST-tagged RET expressed in insect cells • Amino acids: 658-1114 • MW: 77.5 kDa
Cayman Chemical ResolvIn D2 n-3 DPA 10ug
A specialized pro-resolving mediator; formed from n-3 DPA in human leukocytes; reduces TNF-α-induced chemotaxis and adhesion of isolated human neutrophils at 1 nM; reduces peritoneal neutrophil infiltration and exudate levels of IL-6 and CCL2 in a mouse model of zymosan-induced inflammation
Miltenyi Biotec, Inc. CD64 pure, human, REA978, 0,1ml
Identification and enumeration of CD64+ cells by mass cytometry.
This product is subject to the following: Miltenyi Biotec, Inc. Terms and Conditions of Sale For Products and Services
AMID BIOSCIENCES Amid Biosciences, BirA Biotin Protein Ligase, Recombinant, 100 ug
BirA biotin protein ligase is supplied in a 100 ug format. Applications include In vitro biotinylation of AviTag or biotin acceptor peptide tagged proteins, preparation of biotinylated proteins for streptavidin-based assays, ELISA, SPR, BLI, pull-down, AlphaScreen. The enzyme catalyzes site-specific covalent biotin attachment to AviTag-bearing proteins using biotin, ATP, and magnesium-containing reaction conditions. Technical specifications are included below.- Quantity - 100 ug- Source / Expression: Expressed in E. coli cell expression system (amino acids 3–321)- Molecular Weight - 36.2 kDa- Purification Tag - Features an N-terminal His-tag, allowing for easy removal post-reaction using a Ni-NTA column (if the substrate lacks a His-tag)- Purity - Greater than 90%- High Activity - 5,000 Units/µg. 1 Unit biotinylates 1 pmol of AviTag peptide substrate in 30 minutes at 30 C.- Storage - -20 CThis product is for research use only.
Medchemexpress LLC Glyasperin C | 142474-53-1 | 98.9% | 356.41 | 1 MG
Glyasperin C is a potent and reversible noncompetitive inhibitor of neuraminidase with an IC50 of 20% at 200 μM. It is a polyphenol isolated from the roots of *Glycyrrhiza uralensis*.
- Chemical formula: C21H24O5
- Appearance: Solid
- Color: Off-white to light yellow
- Initial source: Plants, Leguminosae, *Glycyrrhiza uralensis* Fisch.
- Shipping: Room temperature in continental US
- Storage: 4°C, sealed, away from moisture and light
- Storage in solvent: -80°C for 6 months or -20°C for 1 month (sealed, away from moisture and light)
- Solubility in vitro: DMSO : 100 mg/mL (280.58 mM); requires ultrasonic