General Cell Based Assays
Genscript Corporation CHO-K1/G15/CXCR5
Recombinant CHO-K1 cells stably overexpress human C-X-C motif chemokine receptor 5 (CXCR5) on the surface and contain high levels of G protein G i to couple with the receptor in downstream signaling pathways
Eurofins Discoverx PathHunter eXpress NMU1R U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0232E3CP0M)
The PathHunter nMU1R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. neuromedin U) based activation of nMU1R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged nMU1R and EA-tagged β-Arrestin-2. Activation of nMU1R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cayman Chemical cGAS TR-FRET Inhibitor Screening Assay Kit, 96 Well
Cayman’s cGAS TR-FRET Inhibitor Screening Assay Kit provides a robust and easy-to-use time-resolved Förster resonance energy transfer (TR-FRET) platform for identifying novel inhibitors of human cGAS, which is a cystosolic dsDNA sensor that detects microbial pathogens. This assay utilizes a mouse anti-rabbit monoclonal immunoglobulin G (IgG) directly labeled with a europium (Eu3+) chelate as a donor molecule and fluorescently labeled 2’3’-cGAMP as the acceptor molecule. In the presence of an anti-2’3’-cGAMP antibody, the donor and acceptor are brought into close proximity resulting in a FRET from the donor to the acceptor upon excitation of the Eu3+-conjugated IgG at 340 nm and an emission from the acceptor at 665 nm. In the assay, production of 2’3’-cGAMP by cGAS in the presence of dsDNA, ATP, and GTP results in the displacement of fluorescently labeled 2’3’-cGAMP from the anti-2’3’-cGAMP antibody, resulting in a loss of.
Eurofins Discoverx PathHunter eXpress EpoR-JAK2 Functional Assay, 10-Plate Kit. (93-0900E3CP16L)
The PathHunter EpoR-JAK2 Functional assay eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting CTKs. This kit assesses EpoR activation via detection of JAK2 mediated phosphorylation-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged EpoR cytokine receptor, an untagged CTK JAK2 and EA-tagged SH2 domain protein. Upon activation of the cytokine receptor, CTK-based receptor phosphorylation leads to SH2-EA recruitment and production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Molecular Devices Cardiotoxicity Assay Kit, Fluorescence, Calcium Indicator, Bulk 10-Plate
The EarlyTox Cardiotoxicity Kit provides a fluorescence-based calcium assay for rapid detection of cardiotoxic compounds in stem cell-derived cardiomyocytes. The bulk kit supplies reagents for high-throughput screening of up to ten plates and uses a calcium-sensitive dye with masking technology to improve signal window and reduce extracellular background.
- Fluorescence-based calcium assay for cardiomyocyte function
- Bulk kit supplies reagents for up to ten plates
- Compatible with 96-, 384-, and 1536-well plate formats
- Includes loading dye, dilution buffer, and reference compounds
- Mix-and-read, no-wash homogeneous protocol
- Optimized for high-throughput fluorescence plate readers and kinetic imaging
Biolegend Alexa FluorR 647 anti-AMPKalph
Alexa Fluor 647 anti-AMPKα Phospho (Thr172) [A20017A]; Isotype: Mouse IgG1, κ; Reactivity: Human, Mouse; Apps: IHC-P, ICFC; Size: 100 μg
Meso Scale Discovery R-PLEX Human IL-36 ASY
The Meso Scale Discovery R-PLEX Human IL-36gamma Assay is a multiplex immunoassay panel that allows simultaneous quantitative measurement of IL-36gamma in human serum plasma and cell culture supernatants It utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity up to 5-logs of dynamic range and low sample volume requirements This assay kit includes a plate coated with capture antibodies detection antibodies labeled with an ECL compound and calibrator and control solutions for generating standard curves and evaluating run validity It allows sensitive reproducible quantification of IL-36gamma levels from human samples
Eurofins Discoverx AssayComplete Cell Plating 26 Reagent, 500. (93-0563R26B)
AssayComplete Cell Plating 26 Reagent is an optimized cell plating reagent for use in plating of Eurofins DiscoverX cell lines for assays. This reagent was optimized for maximal cell health and ligand responsiveness during assays while eliminating hormones and growth components which may lead to increased basal activity. This product is provided as a bottle of 500 mL. Please refer to cell line specific datasheet to determine the recommended cell plating reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Meso Scale Discovery R-PLEX Human ERbB2 ASY
The R-PLEX Human ERBB2 Assay is a multiplex immunoassay panel that measures ERBB2 protein levels in human serum plasma and cell culture supernatants This assay uses electrochemiluminescence detection technology and is compatible with the SECTOR S 600 instrument The panel allows for the simultaneous quantitative measurement of ERBB2 along with other biomarkers This assay has high sensitivity broad dynamic range and requires low sample volume The R-PLEX Human ERBB2 Assay provides a reproducible and robust tool for cancer research and drug development applications
Eurofins Discoverx PathHunter eXpress GPR173 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0380E2ACP1M)
The PathHunter GPR173 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR173 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR173 and EA-tagged β-Arrestin-2. Activation of GPR173 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Immunology Consultants Hamster (CHO) Cathepsin Z - Recombinant, 0.025mg, Lyophilized
This recombinant CHO Cathepsin Z (CTSZ; UniProt Q9EPP7) is expressed in CHO cells with a 6xHIS tag and purified to >95% purity. Under reducing conditions, CTSZ appears at ~37 kDa and is quantified by A280. Cathepsin Z is a lysosomal cysteine protease with both carboxypeptidase and non‑proteolytic functions, including roles in immune regulation and cell adhesion. As a CHO‑derived impurity, CTSZ may degrade therapeutic proteins or alter product quality if not effectively removed. This high‑quality recombinant antigen provides a consistent standard for ELISA calibration, antibody development, and HCP profiling. Its CHO origin ensures biological relevance for impurity studies and purification refinement. Ideal for teams evaluating protease activity, monitoring CTSZ‑related risks, or enhancing downstream control strategies.
Eurofins Discoverx PathHunter eXpress CHRM1 U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0859E3CP0M)
The PathHunter CHRM1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. acetylcholine) based activation of CHRM1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CHRM1 and EA-tagged β-Arrestin-2. Activation of CHRM1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Tocilizumab Bioassay Kit, 10-Plate. (93-1045B3-00110)
The PathHunter Tocilizumab Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. IL-6) induced dimerization of IL-6ST and IL-6R. receptors. This product uses EFC technology. The cell line included overexpresses IL-6ST target protein fused to PK alongside IL-6R target protein fused to EA. Upon ligand-induced dimerization of IL-6ST and IL-6R, detectable EFC signal is produced. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Abcam Calcein AM Assay Kit (Fluorometric)
Calcein AM Assay Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Bioassay Systems EnzyChrom™ Glucose Assay Kit III. For quantitative determination of glucose and evaluation of drug effects on glucose metabolism.
For quantitative determination of glucose and evaluation of drug effects on glucose metabolism. Key Features: Sensitive and accurate. Use as little as 20 µL samples. Linear detection range in 96-well plate: 0.03 to 2 mM (0.54 mg/dL to 36 mg/dL) glucose. Simple and high-throughput. The procedure involves addition of a single working reagent and incubation for 30 min at room temperature. Homogeneous "mix-incubate-measure" type assay. Can be readily automated on HTS liquid handling systems for processing thousands of samples per day. Method: OD565nm. Samples: Serum, plasma, urine, saliva, milk, culture medium, food, beverages etc. Species: All. Procedure: Assay takes 30 min. Kit size: 100 tests. Detection limit: 0.03 mM.