General Cell Based Assays
Abcam Lovastatin (Mevinolin), HMG-CoA reductase inhibitor, 10MG
MW 404.5 Da, Purity >98%. Potent, competitive HMG-CoA reductase inhibitor (Ki = 0.6 nM). Blood-brain barrier permeable. Inhibits in vivo and in vitro cholesterol biosynthesis. Also reduces α-synuclein levels in vitro and in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical Glycogen asy Buffer5X 14mL
A nitroxyl donor reduces MAP and systemic vascular resistance and increases cardiac output in a dog model of microembolism-induced heart failure at four hours post infusion at 7 UG/kg/min for four hours
Abcam TMRM Assay Kit (Mitochondrial Membrane Potential)
TMRM Assay Kit (Mitochondrial Membrane Potential)
The product is subject to the following: Abcam Restricted Use Statement
Echelon Biosciences Research Labs PI(4,5)P2 DiC4 500 ug
Phosphatidylinositol 4,5-bisphosphate diC4 (PI(4,5)P2 diC4) is a synthetic, purified dibutanoyl PI(4,5)P2.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues and is also a substrate for class I phosphoinositide 3-kinase (PI3-K). This item is non returnable
Revvity Health Sciences Inc ViaStain Live Caspase 3/7 Detection for 2D/3D Culture with Hoechst
ViaStain Live Caspase 3/7 Detection for 2D/3D Culture with Hoechst
STEMCELL Technologies Atazanavir, Size: 25 mg
Inhibit HIV-1 protease with atazanavir (IC50 2 - 5 nM Wood). Atazanavir an azapeptide binds to HIV-1 protease and prevents it from producing viral proteins rendering the virus non-infectious as no mature virions are made when HIV-1 protease is inhibited (Kohl et al.). Atazanavir is also a substrate and an inhibitor of cytochrome P450 isozyme 3A (CYP3A) and an inducer of P-glycoprotein (Perloff et al.).
American Research Products Inc FUMARASE KIT COLORIMETIC BA010
5000265242 FUMARASE KIT COLORIMETIC BA010
American Research Products Inc PYRUVATE KIT COLORIMETRIC OR F
5000265204 PYRUVATE KIT COLORIMETRIC OR F
American Research Products Inc LIPOXYGENASE LOX FLUOROMETRIC
5000265094 LIPOXYGENASE LOX FLUOROMETRIC
Eurofins Discoverx cAMP Hunter eXpress GPR35 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0152E2CP2L)
The cAMP Hunter GPR35 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. zaprinast) based activation of GPR35 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type GPR35, a naturally Gi/Go coupled GPCR. Upon activation of GPR35, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery U-PLEX Mouse IL-5 ASY
The Meso Scale Discovery U-PLEX Mouse IL-5 Assay Kit is an electrochemiluminescent immunoassay for quantifying mouse interleukin 5 (IL-5) in serum plasma and cell culture supernatants It uses MSD s SECTOR Imager detecting IL-5 from 0 04 to 1000 pg/mL The kit includes a 96-well plate with capture antibody detection antibody with MSD SULFO-TAG calibrators and diluent The assay takes 3 5 hours and supports research on mouse models of asthma allergies and other IL-5-related immunological diseases
Meso Scale Discovery R-PLEX Human S100B ASY
The Meso Scale Discovery R-PLEX Human S100B Assay QuickPlex 5-PL Kit is a multiplex immunoassay for measuring S100B protein in human serum plasma and cell culture supernatants It uses electrochemiluminescence detection for high sensitivity and rapid results The kit includes a plate with capture antibodies detection antibodies calibrators controls diluent read buffer wash buffer and adhesive seals for one 96-well plate It quantifies S100B levels from 0 04 ng/mL to 1 000 ng/mL requires 50 L of sample and is compatible with Meso Scale Discovery SECTOR Imagers