General Cell Based Assays
Eurofins Discoverx PathHunter Human c-Kit Functional Kinase Cell-Based Assay Kit (U2OS)
The PathHunter Human c-Kit Stable Cell Line Functional Kinase Assay (U2OS) measures c-KIT receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress C5L2 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0645E2CP0M)
The PathHunter C5L2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. C5a) based activation of C5L2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged C5L2 and EA-tagged β-Arrestin-2. Activation of C5L2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx KILR Detection Kit, 200 dp (96-well). (97-0001S)
The KILR Detection Kit is a detection kit intended for use with KILR cell lines or pools when running ADCC or other lysis-based assays. This kit contains exogenous EA as well as EFC substrate to allow for detection of lysis-based release of ProLabel-tagged KILR reporter protein. This kit contains all components required to assay 2 plates (96-well). For detailed product information, User manual and COA, visit www.discoverx.com/products/reagents/detection-kit-97-0001s.
Eurofins Discoverx PathHunter Human IL-27 (IL27RA/IL6ST) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human IL-27 (IL27RA/IL6ST) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of IL27RA/IL6ST. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human PROKR1 Total GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human PROKR1 Stable Cell Line Total GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure PROKR1 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
ADINSTRUMENTS EOG Kit, horizontal/vertical eye movement tracking, includes EOG Pod, shielded lead wires, 100 disposable ECG electrodes
The ADInstruments PTK15 EOG Kit is engineered for precise recording and analysis of both horizontal and vertical eye movements. It's ideal for scientific investigations into ocular phenomena such as slow-tracking and saccades. This kit is designed for immediate deployment in experiments targeting eye movement dynamics.
- Measurement capability: Horizontal and vertical eye movement
- Primary application: Eye position tracking
- Research applications: Slow-tracking, saccades
- Kit contents include: EOG Pod, shielded lead wires, disposable ECG electrodes (100)
- Manufacturer: ADInstruments
Eurofins Discoverx PathHunter Human TNF alpha (IL17RD/TNFR2) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human TNF alpha (IL17RD/TNFR2) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of IL17RD/TNFR2 . This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Cayman Chemical EstradIol 3 DGlucuronIde 10mg
A non-cholestatic regioisomer of E217G that acts as a substrate for MRP2, competing with E217G for MRP2-mediated transport (IC50 = 14.2 µM)
Eurofins Discoverx PathHunter Human NMU1R β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Human NMU1R β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure NMU1R (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress CCKAR CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0190E2CP2L)
The PathHunter CCKAR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. cholecystokinin) based activation of CCKAR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CCKAR and EA-tagged β-Arrestin-2. Activation of CCKAR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter CCR2 Bioassay Kit, 2-Plate. (93-0192Y2-00061)
The PathHunter CCR2 Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. MCP-1/CCL2) based activation of CCR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CCR2 and EA-tagged β-Arrestin-2. Activation of CCR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Eurofins Discoverx PathHunter eXpress OXGR1 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0693E2CP1L)
The PathHunter OXGR1 (GPR80, GPR99) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of OXGR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged OXGR1 and EA-tagged β-Arrestin-2. Activation of OXGR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter eXpress MC4R CHO-K1 GPCR Assay, 2-Plate Kit. (95-0050E2CP2M)
The cAMP Hunter MC4R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. α-melanocyte stimulating hormone) based activation of MC4R GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type MC4R, a naturally Gs coupled GPCR. Upon activation of MC4R, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam BC 11 hydrobromide, Urokinase (uPA) inhibitor, 10MG
MW 290.97 g/mol, Purity >99%. Selective urokinase (uPA) inhibitor (IC₅₀ = 8.2 μM). Shows selectivity over 8 other related enzymes.
The product is subject to the following: Abcam Restricted Use Statement
American Research Products Inc FOXD3 Transcription Factor Activity Assay
FOXD3 Transcription Factor Activity Assay