General Cell Based Assays
Eurofins Discoverx PathHunter Human CHRM1 Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human CHRM1 Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure CHRM1 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Sino Biological Protein Canine IL1RAP 100UG
A DNA sequence encoding the Canine IL1RAP/IL-1RAcP (A0A8C0NSV9) (Ser21-Glu357) was expressed with a polyhistidine tag at the C-terminus
ASSAYQUANT TECHNOLOGIES INC Protein 1000 kin assay AQT0439
PhosphoSens-Kinetic Kinase Activity Kit 1000 assays - AQT0439
Eurofins Discoverx PathHunter eXpress BMPR1A/ACVR2 Dimerization Assay, 2pl Kit. (93-1037E3CP5M)
The PathHunter BMPR1A/ACVR2 Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. BMP-4) induced dimerization of BMPR1A/ACVR2 receptors. This product uses EFC technology. The cell line included overexpresses BMPR1A target protein fused to PK alongside ACVR2 target protein fused to EA. Upon ligand-induced dimerization of BMPR1A/ACVR2, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Indigo Biosciences INDIGO Biosciences Human c-MET / HGFR Reporter Assay System, 384-well, Bio-luminescence
This all-inclusive reporter assay system is for quantifying functional interactions against c-MET or the coupled RAS-MAPK pathway. It uses human cells engineered to express Human c-MET and a luciferase reporter gene, providing a sensitive measure of drug-induced changes in c-MET activity.
- Utilizes human cells engineered to express c-MET and a luciferase reporter gene.
- Quantifies luciferase activity to measure drug-induced c-MET activity.
- Cryo-preservation enables immediate dispensing of reporter cells.
- Includes reporter cells, media, activator, detection reagents, and a 384-well assay plate.
- Bio-luminescence technology offers low background, high-sensitivity, and broad linear dynamic range.
Eurofins Discoverx PathHunter eXpress rHTR2C U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0915E3RCP0M)
The PathHunter rHTR2C eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. serotonin) based activation of rHTR2C GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged rHTR2C and EA-tagged β-Arrestin-2. Activation of rHTR2C stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
ASSAYQUANT TECHNOLOGIES INC Protein 1000 kin assay AQT0426
PhosphoSens-Kinetic Kinase Activity Kit 1000 assays - AQT0426
ASSAYQUANT TECHNOLOGIES INC Protein 1000 kin assay AQT1030
PhosphoSens-Kinetic Kinase Activity Kit 1000 assays - AQT1030
Meso Scale Discovery U-PLEX Human IL-17A/F ASY
The Meso Scale Discovery U-PLEX Human IL-17A/F Assay Kit is a multiplex immunoassay that measures human interleukin 17A and interleukin 17F in cell culture supernatants serum plasma and other biological samples This electrochemiluminescent assay utilizes MSD s proprietary SECTOR Imager and provides high sensitivity a broad dynamic range and requires low sample volume The kit includes a 96-well plate coated with capture antibodies detection antibodies Read Buffer Diluent 2 Calibrator Blend and Wash Buffer It can detect IL-17A in a range of 0 06-1500 pg/mL and IL-17F in a range of 0 10-1500 pg/mL
Eurofins Discoverx PathHunter eXpress ACVR1B/BMPR2 Dimerization Assay, 10pl Kit. (93-1072E3CP5L)
The PathHunter ACVR1B/BMPR2 Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. activin A) induced dimerization of ACVR1B/BMPR2 receptors. This product uses EFC technology. The cell line included overexpresses ACVR1B target protein fused to PK alongside BMPR2 target protein fused to EA. Upon ligand-induced dimerization of ACVR1B/BMPR2, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human CTLA4 Signaling Cell-Based Assay Kit (Jurkat)
The PathHunter Human CTLA4 (SHP1) Signaling Stable Cell Line Assay (Jurkat) measures CTLA4 signal by recruitment of SH2 domain protein to the activated receptor. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human MCHR1 β-Arrestin-1 Cell-Based Assay Kit (U2OS)
The PathHunter Human MCHR1 β-Arrestin-1 Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure MCHR1 (GPCR) activity via recruitment of β-Arrestin-1. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human Complement C5a (C5AR1) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human Complement C5a (C5AR1) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure C5AR1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress GPR107 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0419E2ACP1L)
The PathHunter GPR107 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR107 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR107 and EA-tagged β-Arrestin-2. Activation of GPR107 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.