General Cell Based Assays
Eurofins Discoverx PathHunter eXpress PRLHR CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0302E2CP2M)
The PathHunter PRLHR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. PrRP) based activation of PRLHR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged PRLHR and EA-tagged β-Arrestin-2. Activation of PRLHR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx ADP Hunter Plus, 24 (2,400dp, 384-well). (90-0083M)
The ADP Hunter Plus kit is a detection kit for the measurement of ADP produced as a product of kinase activity. It is used to detect substrate-induced activity of purified or semi-purified kinases. ADP produced by the kinase reacts with intermediate factors to produce a fluorescent dye precursor, which generates signal when combined with peroxide and peroxidase. The kit uses an end-point read. This detection kit contains reagents for 6 plates (384-well). For detailed product information, visit www.discoverx.com/products-applications/biochemical-assays.
Eurofins Discoverx AssayComplete Cell Plating 30 Reagent, 500. (93-0563R30B)
AssayComplete Cell Plating 30 Reagent is an optimized cell plating reagent for use in plating of Eurofins DiscoverX cell lines for assays. This reagent was optimized for maximal cell health and ligand responsiveness during assays while eliminating hormones and growth components which may lead to increased basal activity. This product is provided as a bottle of 500 mL. Please refer to cell line specific datasheet to determine the recommended cell plating reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Eurofins Discoverx cAMP Hunter Follitropin Alfa Bioassay Kit, 10pl. (95-0119Y2-00104)
The cAMP Hunter Follitropin Alfa Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses Follitropin Alfa based activation of FSHR GPCR activity via detection of levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type FSHR, a naturally Gs coupled GPCR. Upon activation of FSHR, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Meso Scale Discovery R-PLEX Human ADAM17 ASYQP
The R-PLEX Human ADAM17 Assay Kit from Meso Scale Discovery is a multiplex immunoassay that measures active ADAM17 in human serum plasma and cell culture supernatants The assay utilizes MSD s electrochemiluminescent detection technology and provides high sensitivity and a broad dynamic range This kit includes a 96-well plate coated with capture antibody detection antibody Read Buffer and calibrator The assay can detect ADAM17 levels between 0 3-1000 pg/mL and requires only 50 L of sample
Eurofins Discoverx cAMP Hunter Follitropin Alfa Bioassay Kit, 2pl. (95-0119Y2-00103)
The cAMP Hunter Follitropin Alfa Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses Follitropin Alfa based activation of FSHR GPCR activity via detection of levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type FSHR, a naturally Gs coupled GPCR. Upon activation of FSHR, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Eurofins Discoverx PathHunter Human Complement C5a (C5AR1) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human Complement C5a (C5AR1) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure C5AR1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Revvity Health Sciences Inc ViaStain Live Caspase 3/7 Detection for 2D/3D Culture with Hoechst
ViaStain Live Caspase 3/7 Detection for 2D/3D Culture with Hoechst
