General Cell Based Assays
Eurofins Discoverx PathHunter Human IL-13 (IL4R/IL13RA1) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human IL-13 (IL4R/IL13RA1) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of IL4R/IL13RA1. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Abcam ITSA-1, HDAC activator, 25MG
MW 292.12 Da, Purity >98%. Cell-permeable HDAC activator. Selective Trichostatin A (ab120850) suppressor. Counteracts Trichostatin A-induced cell cycle arrest. Inhibits Trichostatin A-induced tubulin acetylation. Shows no effect on the activity of other HDAC inhibitors.
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter Human GPR17 β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Human GPR17 β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure GPR17 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter CCR2 Bioassay Kit, 10-Plate. (93-0192Y2-00062)
The PathHunter CCR2 Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. MCP-1/CCL2) based activation of CCR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CCR2 and EA-tagged β-Arrestin-2. Activation of CCR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Eurofins Discoverx AssayComplete Cell Plating 19 Reagent, 500. (93-0563R19B)
AssayComplete Cell Plating 19 Reagent is an optimized cell plating reagent for use in plating of Eurofins DiscoverX cell lines for assays. This reagent was optimized for maximal cell health and ligand responsiveness during assays while eliminating hormones and growth components which may lead to increased basal activity. This product is provided as a bottle of 500 mL. Please refer to cell line specific datasheet to determine the recommended cell plating reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Eurofins Discoverx PathHunter Bioassay Kit ED Detection Kit, 10 (200 dp, 96-well). (93-1043E)
The PathHunter Bioassay ED Detection Kit is a detection kit intended for use with Eurofins DiscoverX's PathHunter Bioassay cells overexpressing ED (ProLabel/PK) but not containing any EA. This kit contains lysis buffer, exogenous EA, and EFC substrate to allow for detection of levels of ED in the assayed cells. This kit contains all components required to assay 2 plates (96-well). For detailed product information, User manual and COA, visit www.discoverx.com/products/reagents/detection-kit-93-1043e.
TRIBIOSCIENCE INC Homocysteine Assay (Colorimetric / Fluorometric) 100 Tests
Tribioscience’s Homocysteine Assay measures homocysteine concentrations in plasma or serum and other bio-samples with coupling enzyme reactions. The resulting fluorescent signal at Ex/Em = 400/465 nm is in proportion to homocysteine concentrations in samples. The kit provides the easiest and most accurate approach to measuring homocysteine levels in a sample. Applications - Measure Homocysteine in a variety of samples.
Eurofins Discoverx PathHunter Mouse OXTR β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Mouse OXTR β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure OXTR (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Abcam RG 108, non-nucleoside DNA methyltransferase inhibitor (DNMT), 10MG
MW 334.3 Da, Purity >99%. Novel, non-nucleoside DNA methyltransferase (DNMT) inhibitor, capable of interacting with the DNMT1 active site (IC₅₀ = 115 nM). Inhibits DNA methylation in human cancer cell lines. Reactivates several epigenetically silenced tumour suppressor genes in vitro. Capable of enhancing the efficiency of induced pluripotent stem cell (iPS) generation.
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress EDG5 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0256E2CP0M)
The PathHunter EDG5 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. S1P) based activation of EDG5 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged EDG5 and EA-tagged β-Arrestin-2. Activation of EDG5 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam AGE (Advanced Glycation End) Assay Kit
AGE (Advanced Glycation End) Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Meso Scale Discovery U-PLEX Mouse TNF- ASY
The Meso Scale Discovery U-PLEX Mouse TNF-alpha Assay is a multiplex immunoassay kit that enables simultaneous measurement of mouse tumor necrosis factor alpha (TNF-alpha) in serum plasma and cell culture supernatants It utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and intra- and inter-assay precision This assay requires 50 L or less sample volume and can be fully automated on the MSD instrument platforms The lower limit of detection is 0 04 pg/mL
Medchemexpress LLC cGAS Human His-SUM 10ug
Recombinant human cyclic GMP-AMP synthase (cGAS) fragment G161-F522, expressed in E. coli and supplied lyophilized with an N-terminal 6xHis-SUMO tag. The protein is purified to >90% and provided with storage and reconstitution guidance to preserve activity for biochemical and structural applications.
- Recombinant human cGAS fragment G161-F522 with N-terminal His-SUMO tag.
- Expressed in E. coli and purified to greater than 90% purity.
- Lyophilized formulation for improved stability and convenient storage.
- Buffer contains trehalose to protect protein during lyophilization.
- Suitable for biochemical assays, enzymatic activity, and structural studies.
- Includes storage and reconstitution guidance to maintain activity.
Abcam Cathepsin B Assay Kit (Magic Red)
Cathepsin B Assay Kit (Magic Red)
The product is subject to the following: Abcam Restricted Use Statement