General Cell Based Assays
ION BIOSCIENCES Brilliant Thallium Assay Express kit - 100 plates
ION Biosciences’ Brilliant Thallium (Tl⁺) Assay Express kit is a total assay solution for multi-well plate-based, high-throughput measurements of Tl⁺ flux through K⁺, Na⁺, non-selective cation channels, and some Na⁺ or K⁺ transporters. ION Biosciences Brilliant Thallium Assay excels in potassium channel assays, standing out among market leaders for its robust signal amplitude, high Z’, customizability, and cost-effectiveness. A potassium channel assay, and so much more. ION’s high-throughput, no wash thallium (Tl⁺) flux assay is an optimal solution for measuring the activity of potassium (K⁺), sodium (Na⁺), and non-selective cation channels and their effectors including transporters and GPCRs. The ION Biosciences’ Brilliant Thallium Assay is also useful for a wide range of effectors of ion channels and transporters including G protein-coupled receptors, lipid and protein kinase, for example. 100-plate kit.
Eurofins Discoverx InCELL Hunter eXpress HEK 293 SMARCA4 Bromodomain Assay, 10-plate Kit. (96-0060E1CP7L)
The InCELL Hunter eXpress HEK 293 SMARCA4 Bromodomain Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with regulators of epigenetics pathways. This kit assesses compound-engagement-based stabilization of SMARCA4 via detection of SMARCA4 levels. This product uses EFC technology. The cell line included overexpresses SMARCA4 target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human GRPR β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Human GRPR β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure GRPR (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter eXpress SSTR3 CHO-K1 GPCR Assay, 2-Plate Kit. (95-0131E2CP2M)
The cAMP Hunter SSTR3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. somatostatin 28) based activation of SSTR3 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type SSTR3, a naturally Gi/Go coupled GPCR. Upon activation of SSTR3, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human CMKLR1 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human CMKLR1 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CMKLR1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human CD200R Signaling Cell-Based Assay Kit (Jurkat)
The PathHunter Human CD200R (DOK2) Signaling Stable Cell Line Assay (Jurkat) measures CD200R signal by recruitment of SH2 domain protein to the activated receptor. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human OXTR Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human OXTR Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure OXTR (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human EphB4 Functional Kinase Cell-Based Assay Kit (U2OS)
The PathHunter Human EphB4 Stable Cell Line Functional Kinase Assay (U2OS) measures EphB4 receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.