General Cell Based Assays
Revvity Health Sciences Inc HTRF Human Total SYK Detection Kit, 500 Assay Points
HTRF Human Total SYK Detection Kit, 500 Assay Points
Medchemexpress LLC cGAS Human His-SUM 50ug
Recombinant human cyclic GMP-AMP synthase (cGAS) fragment (G161-F522) expressed in E. coli and supplied lyophilized with N-terminal 6xHis and SUMO tags to aid purification and solubility. Supplied amount for this item is 50 μg; other pack sizes are available. Activity testing is in progress and not guaranteed. Store lyophilized material frozen and aliquot after reconstitution per manufacturer's guidance.
- Recombinant fragment spanning residues G161-F522.
- N-terminal 6xHis and SUMO tags for purification and solubility.
- Expressed in E. coli for bacterial expression.
- Lyophilized formulation with trehalose for improved stability.
- Available in multiple pack sizes, including 50 μg.
- Activity testing in progress; no guaranteed activity.
- Recommend aliquoting and storage at -20°C or -80°C for long-term preservation.
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-CDK2 (Tyr15) Detection Kit, 50,000 Assay Points
HTRF Human & Mouse Phospho-CDK2 (Tyr15) Detection Kit, 50,000 Assay Points
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-ERK (Thr202/Tyr204) Advanced Detection Kit, 500 Assay Points
HTRF Human & Mouse Phospho-ERK (Thr202/Tyr204) Advanced Detection Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF Human TNF-α / TNFR1 Binding Kit, 10,000 Assay Points
HTRF Human TNF-α / TNFR1 Binding Kit, 10,000 Assay Points
Revvity Health Sciences Inc HTRF Human Phospho-IκKβ (Ser177/181) Detection Kit, 10,000 Assay Points
HTRF Human Phospho-IκKβ (Ser177/181) Detection Kit, 10,000 Assay Points
Cayman Chemical DuP-697 asy Reagent 1ea
An alkaloid with anti-inflammatory activity reduces LPS-induced TNF-a release from and NO production in RAW 264.7 macrophages at 10 30 and 100 UM reduces paw swelling in a rat model of CFA-induced arthritis at 9 and 27 mg/kg reduces colonic inflammatory cytokine levels and maintains mucosal barrier function in a mouse model of DSS-induced colitis from 25-100 mg/kg
Revvity Health Sciences Inc HTRF Human Phospho-AKT2 (Ser473) Detection Kit, 500 Assay Points
HTRF Human Phospho-AKT2 (Ser473) Detection Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF Human Total Phospholamban Detection Kit, 10,000 Assay Points
HTRF Human Total Phospholamban Detection Kit, 10,000 Assay Points
Eurofins Discoverx PathHunter eXpress CHRM2 Activated GPCR Internalization Assay, 2pl Kit. (93-0656E3CP5M)
The PathHunter CHRM2 Activated GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of CHRM2 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged CHRM2. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting CHRM2-arrestin complex is internalized to the early endosome, leading to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cayman Chemical CelBased asy MyeloperoxId 50uL
A peptide hormone selectively binds to MC1R over MC3R MC4R and MC5R (Kis 0.89 10.64 8.18 and 76.9 nM respectively) induces lipolysis in isolated rabbit adipocytes at 1 UM increases plasma levels of glucagon insulin and free fatty acids in fed or fasted rabbits at 45 UG/animal CSF levels are increased in patients with restless legs syndrome with painful symptoms
Cayman Chemical Lipid Droplets Assay Dye Extr
A Y-secretase modulator selectively inhibits the production of AB42 in CHO cells expressing wild-type APP (IC50 9.8 nM) over Notch cleavage to NICD (IC50 >15.8 UM) decreases brain levels of AB42 in rats at 10 and 40 mg/kg decreases CSF levels of AB40 and AB42 and increases levels of AB38 and AB39 without affecting total AB CSF levels in dogs at 20 mg/kg
