General Cell Based Assays
Apexbio Technology LLC ANTI-EGFR PANITUMUMAB-5mg
Anti-ERBB1/EGFR/HER1 Antibody (Panitumumab) (CAS No 339177-26-3) is a monoclonal antibody used in oncology research targeting the epidermal growth factor receptor (EGFR) contributing to the inhibition of cancer cell proliferation Originating from recombinant DNA technology it binds specifically to EGFR blocking the activation of the receptor s intracellular kinase domain which is crucial in pathways such as MAPK and PI3K/AKT known for their role in cell growth and survival In vitro Panitumumab exhibits activity in the nanomolar range demonstrating its efficacy in inhibiting tumor growth It is typically applied in cell line studies such as A431 and HER1/EGFR-expressing transfected models and is employed in animal studies to evaluate anti-tumor activity in xenograft models Additionally it serves as a tool in drug screening for the development of EGFR-targeted therapies Experimental concentrations typically depend on the specific research design
Eurofins Discoverx PathHunter eXpress CSF3R-JAK1 Functional Assay, 10-Plate Kit. (93-0809E3CP16L)
The PathHunter CSF3R-JAK1 Functional assay eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting CTKs. This kit assesses CSF3R activation via detection of JAK1 mediated phosphorylation-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged CSF3R cytokine receptor, an untagged CTK JAK1 and EA-tagged SH2 domain protein. Upon activation of the cytokine receptor, CTK-based receptor phosphorylation leads to SH2-EA recruitment and production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
American Research Products Inc AMERICAN RESEARCH PRODUCTS INC
5000781002 LNP FLUOGREEN SMALL MOL KIT
Eurofins Discoverx cAMP Hunter™ Human CRTH2 Gi Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human CRTH2 Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CRTH2 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Abcam Glycerol Assay Kit (Cell Based)
Glycerol Assay Kit (Cell Based)
The product is subject to the following: Abcam Restricted Use Statement
Cell Signaling Technology PTMScanR Phospho-MAPK Substrate Motif PXpTP Kit 1 Kit
PTMScanR Phospho-MAPK Substrate Motif PXpTP Kit 1 Kit
ACROBiosystems Human Fc gamma RIIA / CD32a (H167) binding Kit (TR-FRET) is expressed from Human, 100 tests
Human Fc gamma RIIA / CD32a (H167) binding Kit (TR-FRET) is expressed from Human
ACROBiosystems Human Fc gamma RIIA / CD32a (R167) binding Kit (TR-FRET) is expressed from Human, 10000 tests
Human Fc gamma RIIA / CD32a (R167) binding Kit (TR-FRET) is expressed from Human