General Cell Based Assays
Abcam Cerivastatin sodium, HMG-CoA reductase inhibitor, 10MG
MW 481.5 Da, Purity >98%. Potent HMG-CoA reductase inhibitor (Ki = 13 nM). Shows higher potency than Lovastatin (ab120614). Enantiomerically pure pyridine derivative. Reduces plasma cholesterol levels in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical Ascorbate Developer 1ea
Cyclic di-AMP-HRP Tracer has been tested and formulated to work exclusively with Cayman’s Cyclic di-AMP ELISA Kit
Cell Biolabs Inc OxiSelect™ In Vitro ROS/RNS Assay Kit (Green Fluorescence), 5x96 assays
The OxiSelect™ In Vitro ROS/RNS Assay Kit is an assay for measuring the total free radical presence of a sample. The assay employs a proprietary quenched fluorogenic probe, DCFH-DiOxyQ), which is based on similar chemistry to the popular DCFH-DA. The DCFH-DiOxyQ probe is first primed with a quench removal reagent, and subsequently stabilized in the highly reactive DCFH form. In this reactive state, ROS and RNS species can react with DCFH, which is rapidly oxidized to the highly fluorescent 2’, 7’-dichlorodihydrofluorescein (DCF) . The DCFH-DiOxyQ probe can react with hydrogen peroxide, peroxyl radical, nitric oxide, and peroxynitrite anion. These free radical molecules are representative of both ROS and RNS, thus allowing for measurement of the total free radical population within a sample. The kit has a detection sensitivity limit of 40 nM for H2O2. Each kit provides sufficient reagents to perform up to 5x96 assays, including standard curve and unknown samples.
Molecular Devices Fatty Acid Uptake Assay Kit, Homogeneous, Fluorescence, 96/384-Well
The QBT Fatty Acid Uptake Assay Kit is a homogeneous, fluorescence-based assay for rapid, real-time measurement of fatty acid uptake in live cells. It uses a BODIPY-dodecanoic acid fluorescent analog with quench technology and is configured for high-throughput screening in 96- and 384-well microplates.
- One-step homogeneous fluorescence assay using a BODIPY-dodecanoic acid analog.
- Proprietary quench-based format for real-time fatty acid uptake monitoring.
- Evaluation kit contains 2 vials, sufficient for two microplates.
- Compatible with 96-well and 384-well microplate formats and bottom-read detection.
- Designed for high-throughput screening of fatty acid transporters and uptake inhibitors.
Eurofins Discoverx PathHunter Human MLNR β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human MLNR β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure MLNR (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human HTR2C (5-HT2C) Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human HTR2C (5-HT2C) Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure HTR2C (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Echelon Biosciences Research Labs SHUTTLE PIP KIT PI(3 4 5)P3
Echelon Biosciences - Shuttle PIP Kit - P-9039 - PI(3,4,5)P3 This item is non returnable
Eurofins Discoverx PathHunter eXpress EDNRB CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0593E2CP0M)
The PathHunter EDNRB eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. endothelin-3) based activation of EDNRB GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged EDNRB and EA-tagged β-Arrestin-2. Activation of EDNRB stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human Heregulin beta 1 (ErbB2-ErbB3) Functional Kinase Cell-Based Assay Kit (U2OS)
The PathHunter Human Heregulin beta 1 (ErbB2-ErbB3) Stable Cell Line Functional Kinase Assay (U2OS) measures ErbB2-ErbB3 receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
ETON BIOSCIENCE INC L-LACTATE ASSAY KIT 5ML
Lactate dehydrogenase converts lactate and NAD+ into pyruvate and NADH. The Lactate Assay Kit is based on the reduction of the terazolium salt INT in a NADH-coupled enzyme reaction to formazan, which exhibits an absorbance maximum at 490 nm.
Eurofins Discoverx PathHunter Mouse Glucagon (GCG Receptor) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Mouse Glucagon (GCGR) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GCGR (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress OXTR Activated GPCR Internalization Assay, 2-Plate Kit. (93-0715E3CP0M)
The PathHunter OXTR Activated GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of OXTR via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged OXTR. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting OXTR-arrestin complex is internalized to the early endosome, leading to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.