General Cell Based Assays
Eurofins Discoverx AssayComplete Cell Plating 19 Reagent, 100. (93-0563R19A)
AssayComplete Cell Plating 19 Reagent is an optimized cell plating reagent for use in plating of Eurofins DiscoverX cell lines for assays. This reagent was optimized for maximal cell health and ligand responsiveness during assays while eliminating hormones and growth components which may lead to increased basal activity. This product is provided as a bottle of 100 mL. Please refer to cell line specific datasheet to determine the recommended cell plating reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Eurofins Discoverx PathHunter eXpress GPR37 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0339E2ACP1L)
The PathHunter GPR37 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR37 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR37 and EA-tagged β-Arrestin-2. Activation of GPR37 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery U-PLEX Human MCP-2 ASY 25 PL
The Meso Scale Discovery U-PLEX Human MCP-2 Assay is a multiplex immunoassay kit that enables simultaneous quantitative measurement of the human chemokine MCP-2 It utilizes MSD s proprietary electrochemiluminescent detection technology and is provided in a convenient all-in-one kit containing plates coated with capture antibodies detection antibodies calibrators and buffers The assay has high sensitivity and wide dynamic range requires low sample volume and provides rapid results It is intended for research use only to monitor MCP-2 levels in cell culture supernatants serum plasma and other biological samples
Abcam Glutathione Peroxidase Activity Assay Kit (Fluorometric)
Glutathione Peroxidase Activity Assay Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Abcam Heme Assay Kit
Heme Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical LIpIdLaunchLNP-0315 Uptake 1ea
Cayman’s LipidLaunch™ LNP-0315 Uptake Kit (Near-Infrared Fluorescence) is intended to serve as a starting point for laboratories to explore the uptake of LNPs in vivo without the need for specialized equipment. Optimal preparation conditions for the encapsulation of nucleic acids with LNPs must be determined by the end user.
Sigma Aldrich Fine Chemicals Biosciences Ras Assay Reagent Raf 1 RB
Product Source Human Ras Binding Domain (RBD residues 1-149) of Raf-1 expressed in E. coli.
Eurofins Discoverx cAMP Hunter eXpress GLP1R CHO-K1 GPCR Assay, 2-Plate Kit. (95-0062E2CP2M)
The cAMP Hunter GLP1R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. exendin-4) based activation of GLP1R GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type GLP1R, a naturally Gs coupled GPCR. Upon activation of GLP1R, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Dojindo Molecular Technologies Inc DNA DAMAGE QUANTIFIC KIT (20 SAMPLES) is a colorimetric microplate assay and can determine the number of abasic sites in genomic DNA samples.
Oxidative damage to DNA is a result of its interaction with reactive oxygen species (ROS), in particular the hydroxy radical. Hydroxy radicals, which are produced from superoxide anion and hydrogen peroxide by the Fenton reaction, produce multiple modifications in DNA. Oxidative attacks by hydroxy radicals on the deoxyribose moiety leads to the release of free bases from DNA, generating strand breaks with various sugar modifications and simple abasic sites (AP sites). In fact, AP sites are one of the major types of damage generated by ROS. The Aldehyde Reactive Probe reacts specifically with an aldehyde group present on the open ring form of the AP sites. DNA Damage Quantification Kit contains all the necessary solutions for detecting between 1 to 40 AP sites per 1 x 105 base pairs.
Eurofins Discoverx KILR Detection Kit, 2,500 dp (96-well). (97-0001L)
The KILR Detection Kit is a detection kit intended for use with KILR cell lines or pools when running ADCC or other lysis-based assays. This kit contains exogenous EA as well as EFC substrate to allow for detection of lysis-based release of ProLabel-tagged KILR reporter protein. This kit contains all components required to assay 25 plates (96-well). For detailed product information, User manual and COA, visit www.discoverx.com/products/reagents/detection-kit-97-0001l.
Eurofins Discoverx PathHunter Mouse GLP-1 (GLP-1 Receptor) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Mouse GLP-1 (GLP1R) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GLP1R (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human LHCGR Gs Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human LHCGR Gs Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure LHCGR (GPCR) activity via increased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Mouse GLP-1 (GLP-1 Receptor) β-Arrestin-1 Cell-Based Assay Kit (CHO-K1)
The PathHunter Mouse GLP-1 (GLP1R) β-Arrestin-1 Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GLP1R (GPCR) activity via recruitment of β-Arrestin-1. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress GPR23 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0336E2ACP1L)
The PathHunter GPR23 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR23 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR23 and EA-tagged β-Arrestin-2. Activation of GPR23 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.