Protein Purification
Aprotinin, Analytical Grade, MP Biomedicals™
Forms stable complexes with enzymes. Aprotinin, Analytical Grade, MP Biomedicals is a competitive serine proteinase inhibitor that works by blocking the active sites of enzymes. This binding is reversible with most aprotinin-protease complexes, dissociati
MilliporeSigma™ Calbiochem™ Cathepsin G Substrate IV, Fluorogenic
An internally quenched fluorogenic peptide substrate (Mca/Anb as fluorophore/quencher) that is preferentially cleaved by cathepsin G between Gnf and Ser with high efficiency and selectivity.
MilliporeSigma™ Calbiochem™ S-Methyl-L-thiocitrulline, Dihydrochloride
A cell-permeable inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC50 = 300nM) compared to the endothelial enzyme (IC50 = 5.4μM).
MilliporeSigma™ Calbiochem™ NF-κB Activation Inhibitor
The NF-κB Activation Inhibitor, also referenced under CAS 545380-34-5, controls the biological activity of NF-κB. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ SB 203580
SB 203580, CAS 152121-47-6, is a highly specific, potent, cell-permeable, selective, reversible, and ATP-competitive inhibitor of p38 MAP kinase (IC50 = 34 nM in vitro, 600 nM in cells).
MilliporeSigma™ Calbiochem™ ETYA
Inhibits arachidonic acid uptake and the activities of arachidonic acid specific and non-specific acyl-CoA synthetases.
MilliporeSigma™ Calbiochem™ IKKε/TBK1 Inhibitor II, MRT67307
A cell-permeable, potent, ATP-competitive, and reversible dual kinase inhibitor of TBK1/IKKε (IC50 = 19 and 160 nM, respectively).
MilliporeSigma™ Calbiochem™ NFAT Inhibitor, Cell-Permeable
The NFAT Inhibitor, Cell-Permeable controls the biological activity of NFAT. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ TGF-β RI Kinase Inhibitor IV
TGF-β RI Kinase Inhibitor IV, CAS 909910-43-6, is a cell-permeable, selective inhibitor of ALK-4/5/7-mediated signaling (IC50 = 45, 12, and 7.5 nM, respectively).
MilliporeSigma™ Calbiochem™ Autophagy Inducer, STF-62247
A cell-permeable autophagy inducer that selectively induces non-apoptotic cell death in VHL-deficient, but not VHL-expressing, renal carcinoma cells both in vitro and in mice in vivo.
MilliporeSigma™ Calbiochem™ Topoisomerase IIα Inhibitor, TSC24
The Topoisomerase IIα Inhibitor, TSC24 controls the biological activity of Topoisomerase. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ SNAPtide™ Botulinum Toxin A Substrate, Fluorogenic
SNAPtide™ Botulinum Toxin A Substrate, Fluorogenic, is a synthetic peptide that acts as a FRET substrate with the fluorophore o-aminobenzoic acid and the acceptor chromophore 2,4-dinitrophenol (DNP).
MilliporeSigma™ Calbiochem™ IKK Inhibitor VII
The IKK Inhibitor VII, also referenced under CAS 873225-46-8, controls the biological activity of IKK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ OxPhos Inhibitor, VLX600
A cell-permeable compound with cytotoxicity towards quiescent cells in colon cancer 3-D microtissues (≈6 μM). Reduces mitochondrial oxidative phosphorylation in tumor cells.
MilliporeSigma™ Calbiochem™ bpV(bipy)
A potent inhibitor of phosphotyrosine phosphatase (Ki = 100 nM for insulin receptor dephosphorylation).