Protein Purification
MilliporeSigma™ Calbiochem™ β-Secretase Inhibitor IV
β-Secretase Inhibitor IV, CAS 797035-11-1, is a cell-permeable inhibitor that binds to BACE-1 active site and blocks its proteolytic activity (IC50 = 15 nM for human BACE-1).
MilliporeSigma™ Calbiochem™ Sialyltransferase Inhibitor, 3Fax-Peracetyl Neu5Ac
The Sialyltransferase Inhibitor, 3Fax-Peracetyl Neu5Ac controls the biological activity of Sialyltransferase.
MilliporeSigma™ Calbiochem™ Sodium Salicylate
A cell-permeable, non-steroidal anti-inflammatory agent that interferes with TNF-induced NF-κB activation by inhibiting phosphorylation and subsequent degradation of the IκB-α protein.
MilliporeSigma™ Calbiochem™ InSolution™ SU6656
A potent inhibitor of Src-family protein tyrosine kinases
MilliporeSigma™ Calbiochem™ Tamoxifen Citrate
Tamoxifen is a potent synthetic anti-estrogenic agent.
MilliporeSigma™ Calbiochem™ SU5402
SU5402, CAS 215543-92-3, is a cell-permeable, reversible, and ATP-competitive inhibitor of the tyrosine kinase activity of FGFR1 (IC50 = 10 to 20 μM in the presence of 1 mM ATP).
MilliporeSigma™ Calbiochem™ SB 203580
SB 203580, CAS 152121-47-6, is a highly specific, potent, cell-permeable, selective, reversible, and ATP-competitive inhibitor of p38 MAP kinase (IC50 = 34 nM in vitro, 600 nM in cells).
MilliporeSigma™ Calbiochem™ Quinacrine, Dihydrochloride
A non-specific phospholipase A2 (PLA2) inhibitor.
MilliporeSigma™ Calbiochem™ Rolipram
A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50 = 800 nM).
MilliporeSigma™ Calbiochem™ Quercetin, Dihydrate
A cell-permeable and reversible inhibitor of PIM1 kinase (IC50 = 43nM), PI 3-K (IC50 = 3.8μM) and phospholipase A2
MilliporeSigma™ Calbiochem™ Ro-20-1724
A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50 = 2 μM).
MilliporeSigma™ Calbiochem™ RAGE Antagonist, FPS-ZM1
RAGE Antagonist, FPS-ZM1, is a blood-brain-barrier permeant blocker of RAGE V domain-mediated ligand binding (K
MilliporeSigma™ Calbiochem™ Roscovitine
A potent, reversible, and selective inhibitor of Cdks that exhibits about 10-fold greater efficacy towards p34-cdk1 and p33-cdk2 and 20-fold greater efficacy towards p33-cdk5 relative to Olomoucine.
MilliporeSigma™ Calbiochem™ SB 203580, Hydrochloride
SB 203580, Hydrochloride, CAS 869185-85-3, is a water-soluble form of SB 203580. A highly potent, selective, ATP-competitive inhibitor of p38 MAP Kinase (IC50 = 34nM in vitro, 600nM in cells).
MilliporeSigma™ Calbiochem™ Rac Inhibitor III, EHop-016
The Rac Inhibitor III, EHop-016 controls the biological activity of Rac. This small molecule/inhibitor is primarily used for Membrane applications.