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The Carbonic Anhydrase IX/XII Inhibitor controls the biological activity of Carbonic Anhydrase IX/XII. This small molecule/inhibitor is primarily used for Cancer applications.
The JMJD Histone Demethylase Inhibitor III controls the biological activity of JMJD Histone Demethylase. This small molecule/inhibitor is primarily used for Cell Structure applications.
A cell-permeable indolylphenylthienopyrimidinone compound that increases mitochondrial content without affecting the cell size (∽10μM). Reduces mitochondrial protein turnover without affecting any known transcriptional programs of mitochondrial biogenesis.
A diphenyl substituted imidazole based compound that directly and selectively targets TLR1/2 and induces their dimerization and activates TLR1 and 2 signaling leading to NF-κB and AP-1 activation ( K D = 182 and 478 nM, respectively; EC50
Thermo Scientific™ CaptureSelect™ AAT-XL Affinity Matrix has been specifically designed for the purification of native human alpha-1 antitrypsin (AAT) from complex sources like plasma/serum and recombinant human AAT from cell culture supernatants.
The Protease Inhibitor Cocktail Set IV controls the activity of Protease. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
The β-Catenin/Tcf Inhibitor, FH535, also referenced under CAS 108409-83-2, controls the biological activity of β-Catenin/Tcf. This small molecule/inhibitor is primarily used for Cell Signaling applications.
The HIF-1α Translation Inhibitor, KC7F2, also referenced under CAS 927822-86-4, controls the biological activity of HIF-1α. This small molecule/inhibitor is primarily used for Cell Structure applications.
A cell-permeable benzodiazepine that suppresses CBFα/Runx1-CBFβ transactivation activity (25μM; 293-0 cells) via direct bindings to both subunits of the heterodimeric transcription factor complex
The Myosin Light Chain Kinase Inhibitor Peptide 18 controls the biological activity of Myosin Light Chain Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
Protease Inhibitor Cocktail is used to prevent protein degradation after lysing cells. The product is a mixture of six different protease inhibitors with different target protease specificities.