Cayman Chemical UGT8 InhIbItr 19 25mg
An inhibitor of UGT8 (IC50 = 0.2 nM); selective for UGT8 over UGT1A1, -1A6, -2B7, -2B15, and -2B17 (IC50s = >10 µM for all); inhibits the synthesis of GalCer and SFT in juvenile mouse brain (ED50s = <3 mg/kg for both) and adult mouse kidney at 3, 10, and 30 mg/kg