Protein Purification
Sigma Aldrich Fine Chemicals Biosciences E-64d | 88321-09-9 | MFCD00132883 | 1mg
E-64d | Mol Wt: 342.43 | 88321-09-9MFCD00132883 | 1mg
CPC Scientific Ac-Asp-Glu-Val-Asp-CMK 1MG
ONE-LETTER SEQUENCE: Ac-DEVD-CMKMOLECULAR FORMULA: C21H31N4O11Cl1MOLECULAR WEIGHT:550.95STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [285570-60-7], SYNONYMS: Ac-Asp-Glu-Val-Asp-chloromethylketoneRESEARCH AREA: Apoptosis
AG Scientific Inc E-64, 5 MG
E-64 is an Irreversible, potent and highly selective inhibitor of cysteine proteases. It does not affect cysteine residues in other enzymes. E64 acts by forming a thioether bond with the thiol of the active cysteine. E-64 will not inhibit serine proteases (except trypsin) but inhibits activation-induced programmed cell death and restores defective immune responses in HIV. Specific active site titrant.CAS Number: 66701-25-5Molecular Weight: 357.4Chemical Formula: C15H27N5O5Solubility: Up to 20mg/ml in water, Up to 25mg/ml in DMSOStorage Temperature: -20CResearch or further manufacturing use only, not for food or drug use.
Apexbio Technology LLC Potent PI3K inhibitor 957054-30-7. MFCD11616196
Potent PI3K inhibitor 957054-30-7. MFCD11616196
Apexbio Technology LLC K-Ras(G12C) inhibitor 9 1469337-91-4 5mg
K-Ras(G12C) inhibitor 9 (CAS 1469337-91-4) is a covalent small molecule that selectively targets the oncogenic K-Ras(G12C) mutant protein Acting as an allosteric inhibitor it irreversibly binds to the mutant K-Ras interfering with the binding of GTP and GDP and disrupts interactions with effector proteins such as B-Raf and C-Raf In vitro studies show that treatment with 10 M K-Ras(G12C) inhibitor 9 reduces viability and increases apoptosis in K-Ras(G12C)-mutant lung cancer cell lines including H1792 Calu-1 H358 and H23 This compound is a valuable research tool for investigating K-Ras-driven cancer signaling and mutant-selective therapeutic strategies
Apexbio Technology LLC Calpain Inhibitor II, ALLM, 5mg. Cas: 136632-32-1 MFCD: NA. Calpain inhibitor
Calpain inhibitor. Calpain Inhibitor II, ALLM 5mg. 136632-32-1.
Selleck Chemical LLC R406 (free base) 50mg 841290-80-0
R406 (free base) is a potent Syk inhibitor with IC50 of 41 nM in a cell-free assay, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. R406 (free base) triggers apoptosis. Phase 1. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC AZD7762 5mg 860352-01-8
AZD7762 is a potent and selective inhibitor of Chk1 with IC50 of 5 nM in a cell-free assay. It is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck. Phase 1. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Crescent Chemical Co Inc E-64 RESEARCH GRADE
E-64 research grade Inhibitor for papain and other cysteine (thiol) proteases. Effects on metastasis formation in mice (5). Size - 5MG Storage Conditions - -15 °C TO -25 °C Catalog Number - 21100.01 CAS 66701-25-5
Cayman Chemical IL-4 InhIbItr 1mg
An IL-4 inhibitor; binds to IL-4 (Kd = 1.8 μM); inhibits IL-4 activity in a cell-based reporter assay (EC50 = 1.81 μM); selective for IL-4 over IL-13 (EC50 = 18.2 μM); inhibits IL-4-induced STAT6 phosphorylation in THP-1 monocytes (EC50 = 3.1 μM)
Medchemexpress LLC Tie2 kinase inhibitor 1 | 948557-43-5 | MFCD18384977 | 439.53 g/mol | C26H21N3O2S | 50 MG
Tie2 kinase inhibitor 1 is a small-molecule, ATP-site-targeting inhibitor selective for the Tie2 (TEK) receptor tyrosine kinase. It exhibits in vitro potency with reported anti-cancer activity and is supplied for research use only.
- Selective Tie2 kinase inhibition (IC50 250 nM).
- Small-molecule, cell-permeable inhibitor.
- Demonstrated anti-cancer activity in published studies.
- Supplied for research use only, not for human or clinical use.
- Molecular formula C26H21N3O2S; molecular weight 439.53 g/mol.
- CAS number 948557-43-5.
- Provided with SDS for safe handling and storage.
Cayman Chemical mP-3 InhIbItr VIII 500ug
A cell permeable sulfonamide-based hydroxamic acid that binds to the active site of MMP-3 (Ki = 23 nM) and prevents its activity; inhibits mouse macrophage metalloelastase MME/MMP-12 (IC50 = 13 nM)
Selleck Chemical LLC Degrasyn (WP1130) 50mg 856243-80-6
Degrasyn (WP1130) is a selective deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor and also suppresses Bcr/Abl, also a JAK2 transducer (without affecting 20S proteasome) and activator of transcription (STAT). Degrasyn (WP1130) induces apoptosis and blocks autophagy. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC IDH1 Inhibitor 8 | 1448346-63-1 | 99.0% | 582.96 | 1 MG
IDH1 Inhibitor 8 (91) is an isocitrate dehydrogenase 1 (IDH1) inhibitor. It is intended for use in cancer research. This product is for research use only and is not sold to patients.
- Target: Isocitrate dehydrogenase 1 (IDH1)
- Application: Cancer research
- Appearance: Solid, white to off-white
- Solubility: Soluble in DMSO (100 mg/mL, 171.54 mM, with ultrasonic; use newly opened DMSO)
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: 4°C, protect from light. In solvent: -80°C for 6 months; -20°C for 1 month (protect from light).